scholarly journals A pain in the skin. Regenerating nerve sprouts are distinctly associated with ongoing burning pain in patients with diabetes

2018 ◽  
Vol 22 (10) ◽  
pp. 1727-1734 ◽  
Author(s):  
E. Galosi ◽  
S. La Cesa ◽  
G. Di Stefano ◽  
P. Karlsson ◽  
A. Fasolino ◽  
...  
1997 ◽  
Vol 87 (3) ◽  
pp. 117-124 ◽  
Author(s):  
SM Goldman ◽  
JD Funk ◽  
VM Christensen

Spinal stenosis, involving pressure on either the central spinal cord or nerve root exiting the spinal canal, can cause a variety of symptoms in the lower extremities. A classic symptom is that of neurogenic claudication, involving leg pain and weakness brought on by walking. The pain is relieved by sitting or lying down, not by standing and resting as would be seen in arterial insufficiency-induced claudication. Other symptoms of spinal stenosis can involve paresthesia, weakness or cramping in one or both extremities, rest pain, or burning pain, and are commonly misdiagnosed as peripheral neuropathy, especially in patients with diabetes. Symptoms are often chronic, frequently missed, or misdiagnosed in the medical community, and may cause severe disability or reduction in the quality of life. Spinal stenosis is in some patients the unidentified cause of failure of treatment of foot and leg pain. Podiatric physicians, who focus on the patient's lower extremities, are in a unique position to be able to identify spinal stenosis and facilitate appropriate treatment. The authors provide current information regarding symptoms of spinal stenosis, a guide to diagnosis including the anatomical etiologies, and a basic understanding of treatment.


Author(s):  
Bruce R. Pachter

Diabetes mellitus is one of the commonest causes of neuropathy. Diabetic neuropathy is a heterogeneous group of neuropathic disorders to which patients with diabetes mellitus are susceptible; more than one kind of neuropathy can frequently occur in the same individual. Abnormalities are also known to occur in nearly every anatomic subdivision of the eye in diabetic patients. Oculomotor palsy appears to be common in diabetes mellitus for their occurrence in isolation to suggest diabetes. Nerves to the external ocular muscles are most commonly affected, particularly the oculomotor or third cranial nerve. The third nerve palsy of diabetes is characteristic, being of sudden onset, accompanied by orbital and retro-orbital pain, often associated with complete involvement of the external ocular muscles innervated by the nerve. While the human and experimental animal literature is replete with studies on the peripheral nerves in diabetes mellitus, there is but a paucity of reported studies dealing with the oculomotor nerves and their associated extraocular muscles (EOMs).


2017 ◽  
Vol 23 ◽  
pp. 290
Author(s):  
Vamsi Kolukula ◽  
Jayashree Gopal ◽  
Shantharam Duvuru ◽  
Kalpana Dash ◽  
Sanjiv Shah ◽  
...  

2005 ◽  
Vol 11 ◽  
pp. 16
Author(s):  
Sandeep Kumar Mathur ◽  
Piyush Chandra ◽  
Sandhya Mishra ◽  
Piyush Ajmera ◽  
Praveen Sharma

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