One-Pot Successive Turbo Grignard Reactions for the Facile Synthesis of α-Aryl-α-Trifluoromethyl Alcohols

2020 ◽  
Vol 2020 (29) ◽  
pp. 4487-4493
Author(s):  
Ryunosuke Kani ◽  
Toshiyasu Inuzuka ◽  
Yasuhiro Kubota ◽  
Kazumasa Funabiki
Keyword(s):  
Facile Synthesis ◽  
One Pot ◽  
Grignard Reactions

scholarly journals Cover Feature: One-Pot Successive Turbo Grignard Reactions for the Facile Synthesis of α-Aryl-α-Trifluoromethyl Alcohols (Eur. J. Org. Chem. 29/2020)

2020 ◽  
Vol 2020 (29) ◽  
pp. 4434-4434
Author(s):  
Ryunosuke Kani ◽  
Toshiyasu Inuzuka ◽  
Yasuhiro Kubota ◽  
Kazumasa Funabiki
Keyword(s):  
Facile Synthesis ◽  
One Pot ◽  
Grignard Reactions

Synthesis of Pyrrolo[1,2-a][1,6]- and [1,8]naphthyridines by Alkyne-Carbonyl Metathesis

Synthesis ◽  
2020 ◽  
Author(s):  
Peter Ehlers ◽  
Peter Langer ◽  
Marian Blanco Ponce ◽  
Silvio Parpart ◽  
Alexander Villinger ◽  
...  
Keyword(s):  
Heterocyclic Compounds ◽  
Metathesis Reaction ◽  
Synthetic Methodology ◽  
Facile Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Metal Free ◽  
Modular Synthesis

AbstractA concise and modular synthesis of pyrrolo[1,2-a][1,6]- and [1,8]naphthyridines by a one-pot two-step reaction consisting of electrophilic acylation followed by an alkyne-carbonyl-metathesis reaction as the final cyclization step is reported. This developed synthetic methodology allows the facile synthesis of these heterocyclic core structures in mainly high overall yields under metal-free conditions. Reaction conditions are carefully optimized and display a novel supplement to access these tricyclic heterocyclic compounds.

Facile Synthesis of Nitrogen-Doped [(6.)m8]nCyclacene Carbon Nanobelts by a One-Pot Self-Condensation Reaction

2021 ◽  
Vol 143 (7) ◽  
pp. 2716-2721
Author(s):  
Jun Zhu ◽  
Yi Han ◽  
Yong Ni ◽  
Guangwu Li ◽  
Jishan Wu
Keyword(s):  
Condensation Reaction ◽  
Facile Synthesis ◽  
One Pot ◽  
Nitrogen Doped

ChemInform Abstract: Facile Synthesis of Multifunctional Pyrrole[2,1-a]isoquinolin-3(2H)-ones via Sulfa-Michael-Triggered One-Pot Reactions.

ChemInform ◽  
2016 ◽  
Vol 47 (25) ◽  
Author(s):  
Tian-You Qin ◽  
Lu Cheng ◽  
Ho-Chol Jang ◽  
Sean Xiao-An Zhang ◽  
Wei-Wei Liao
Keyword(s):  
Facile Synthesis ◽  
One Pot

One-pot, facile synthesis of well-defined molecular brush copolymers by a tandem RAFT and ROMP, “Grafting-through” strategy

2012 ◽  
Vol 50 (9) ◽  
pp. 1681-1688 ◽  
Author(s):  
Ang Li ◽  
Jun Ma ◽  
Guorong Sun ◽  
Zhou Li ◽  
Sangho Cho ◽  
...  
Keyword(s):  
Facile Synthesis ◽  
One Pot ◽  
Grafting Through

Facile Synthesis of Fe2O3Nanocrystals without Fe(CO)5Precursor and One-Pot Synthesis of Highly Fluorescent Fe2O3-CdSe Nanocomposites

2009 ◽  
Vol 21 (8) ◽  
pp. 869-873 ◽  
Author(s):  
Chung Yen Ang ◽  
Louise Giam ◽  
Zheng Ming Chan ◽  
Alex W. H. Lin ◽  
Hongwei Gu ◽  
...  
Keyword(s):  
Facile Synthesis ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

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