A Transition-Metal-Free One-Pot Cascade Process for Transformation of Primary Alcohols (RCH2 OH) to Nitriles (RCN) Mediated by SO2 F2

2019 ◽  
Vol 2019 (20) ◽  
pp. 3190-3194 ◽  
Author(s):  
Ying Jiang ◽  
Bing Sun ◽  
Wan-Yin Fang ◽  
Hua-Li Qin
Keyword(s):  
Transition Metal ◽  
Cascade Process ◽  
Primary Alcohols ◽  
One Pot ◽  
Metal Free

scholarly journals SO2F2-Mediated one-pot cascade process for transformation of aldehydes (RCHO) to cyanamides (RNHCN)

RSC Advances ◽  
2020 ◽  
Vol 10 (29) ◽  
pp. 17288-17292 ◽  
Author(s):  
Yiyong Zhao ◽  
Junjie Wei ◽  
Shuting Ge ◽  
Guofu Zhang ◽  
Chengrong Ding
Keyword(s):  
Transition Metal ◽  
Nitrogen Source ◽  
Functional Group ◽  
Cascade Process ◽  
One Pot ◽  
Metal Free ◽  
Work Up

Our gram-scale process uses abundant and inexpensive aldehydes, a clean nitrogen source, requires no additional carbon atoms, is transition-metal free, and features easy work-up and excellent functional group compatibility.

A cascade process for directly converting nitriles (RCN) to cyanamides (RNHCN) via SO2F2-activated Tiemann rearrangement

2019 ◽  
Vol 17 (33) ◽  
pp. 7684-7688 ◽  
Author(s):  
Guofu Zhang ◽  
Yiyong Zhao ◽  
Chengrong Ding
Keyword(s):  
Transition Metal ◽  
Functional Group ◽  
Cascade Process ◽  
One Pot ◽  
Metal Free ◽  
Work Up

A one-pot transition metal-free methodology for cyanamide preparation using readily available materials with easy work-up, wide substrate scope and great functional group-tolerability up to the gram scale.

Facile One-Pot Transformation of Primary Alcohols into 3-Aryl- and 3-Alkyl-isoxazoles and -pyrazoles

Synthesis ◽  
2019 ◽  
Vol 51 (19) ◽  
pp. 3723-3735 ◽  
Author(s):  
Eiji Kobayashi ◽  
Hideo Togo
Keyword(s):  
Transition Metal ◽  
Primary Alcohols ◽  
Successive Treatment ◽  
One Pot ◽  
Metal Free ◽  
Methyl Sulfide

Various primary alcohols were smoothly transformed into 3-aryl- and 3-alkylisoxazoles in good yields in one pot by successive treatment with PhI(OAc)2 in the presence of TEMPO, NH2OH, and then NCS, followed by reaction with alkynes in the presence of Et3N. Similarly, various primary alcohols were smoothly transformed into 3-aryl- and 3-alkylpyrazoles in good yields in one pot by successive treatment with PhI(OAc)2 in the presence of TEMPO, PhNHNH2, and then NCS and decyl methyl sulfide, followed by reaction with alkynes in the presence of Et3N. Thus, both 3-aryl- and 3-alkylisoxazoles, and 3-aryl- and 3-alkylpyrazoles could be prepared from readily available primary alcohols in one pot under transition-metal-free conditions.

scholarly journals An entry to 2-(cyclobut-1-en-1-yl)-1H-indoles through a cyclobutenylation/deprotection cascade

2021 ◽  
Author(s):  
Philipp Natho ◽  
Zeyu Yang ◽  
Lewis Allen ◽  
Juliette Rey ◽  
Andrew J P White ◽  
...  
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
Mild Conditions

A transition-metal-free strategy for the synthesis of 2-(cyclobut-1-en-1-yl)-1H-indoles under mild conditions is described herein. A series of substituted 2-(cyclobut-1-en-1-yl)-1H-indoles are accessed by a one-pot cyclobutenylation/deprotection cascade from N-Boc protected indoles....

ChemInform Abstract: Transition Metal Free Intramolecular S-Arylation: One-Pot Synthesis of Thiochromen-4-ones.

ChemInform ◽  
2014 ◽  
Vol 45 (13) ◽  
pp. no-no
Author(s):  
T. A. Jenifer Vijay ◽  
Kebbahalli N. Nandeesh ◽  
Goravanahalli M. Raghavendra ◽  
Kanchugarakoppal S. Rangappa ◽  
Kempegowda Mantelingu
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis

ChemInform Abstract: A One-Pot Transition Metal Free Tandem Process to 1,4-Benzodiazepine Scaffolds.

ChemInform ◽  
2013 ◽  
Vol 44 (17) ◽  
pp. no-no
Author(s):  
Yanqiu Li ◽  
Chunjing Zhan ◽  
Bingchuan Yang ◽  
Xiaoqun Cao ◽  
Chen Ma
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
Tandem Process

One-pot synthesis of thioesters with sodium thiosulfate as a sulfur surrogate under transition metal-free conditions

2018 ◽  
Vol 16 (11) ◽  
pp. 1871-1881 ◽  
Author(s):  
Yen-Sen Liao ◽  
Chien-Fu Liang
Keyword(s):  
Transition Metal ◽  
Sodium Thiosulfate ◽  
Sulfur Source ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis

We have developed a one-pot reaction to provide thioester derivativesviasodium thiosulfate as a sulfur source under transition metal-free conditions.

One-pot transition-metal free transamidation to sterically hindered amides

2018 ◽  
Vol 5 (20) ◽  
pp. 2950-2954 ◽  
Author(s):  
Weijie Guo ◽  
Jingjun Huang ◽  
Hongxiang Wu ◽  
Tingting Liu ◽  
Zhongfeng Luo ◽  
...  
Keyword(s):  
Transition Metal ◽  
Good Yield ◽  
One Pot ◽  
Metal Free ◽  
Highly Efficient ◽  
Sterically Hindered

A highly efficient one-pot transamidation of primary amides has been developed under transition-metal free conditions, generating a variety of amides including hindered amides in good yield (up to 86%) catalyzed by CsF.

Sign in / Sign up

Export Citation Format

Share Document