From Cyclic Ketimines to α-Substituted Cyclic Amino Acids and their Derivatives: Influence of Ring Size and Substituents on Stability and Reactivity of Cyclic Aminonitriles

2018 ◽  
Vol 2019 (4) ◽  
pp. 625-632 ◽  
Author(s):  
Natalia G. Voznesenskaia ◽  
Olga. I. Shmatova ◽  
Anna A. Sosnova ◽  
Valentine G. Nenajdenko
Keyword(s):  
Amino Acids ◽  
Ring Size ◽  
Cyclic Amino Acids

Pd-Catalyzed directedCH-(hetero)arylation of cyclic α-amino acids: effects of substituents and the ring size

2019 ◽  
Vol 17 (17) ◽  
pp. 4342-4349 ◽  
Author(s):  
Valeriia Hutskalova ◽  
Pavel K. Mykhailiuk
Keyword(s):  
Amino Acids ◽  
Systematic Study ◽  
Ring Size ◽  
Directing Group ◽  
First Time ◽  
Cyclic Amino Acids

A systematic study on the directed Pd-catalyzed (hetero)arylation of 26 substituted cyclic α-amino acids at the C(3)-atom was performed. For the first time, the 7- and 8-membered cyclic amino acids were introduced to C–H activation. 8–Aminoquinoline was used as a directing group.

Use of hydrolases for the synthesis of cyclic amino acids

Tetrahedron ◽  
2004 ◽  
Vol 60 (3) ◽  
pp. 717-728 ◽  
Author(s):  
Richard C Lloyd ◽  
Michael C Lloyd ◽  
Mark E.B Smith ◽  
Karen E Holt ◽  
Jonathan P Swift ◽  
...  
Keyword(s):  
Amino Acids ◽  
Cyclic Amino Acids

ChemInform Abstract: Oxidative Decarboxylation of Cyclic Amino Acids and Dehydrogenation of Cyclic Secondary Amines with Iodosobenzene.

ChemInform ◽  
1989 ◽  
Vol 20 (26) ◽  
Author(s):  
M. OCHIAI ◽  
M. INENAGA ◽  
Y. NAGAO ◽  
R. M. MORIARTY ◽  
R. K. VAID ◽  
...  
Keyword(s):  
Amino Acids ◽  
Secondary Amines ◽  
Oxidative Decarboxylation ◽  
Cyclic Amino Acids

H2O2-oxidation of α-aminoisobutyric and cyclic amino acids catalyzed by iron(III) isoindoline complexes

Polyhedron ◽  
2015 ◽  
Vol 89 ◽  
pp. 91-95 ◽  
Author(s):  
Dóra Lakk-Bogáth ◽  
Miklós Harasztia ◽  
Róbert Csonka ◽  
Gábor Speier ◽  
József Kaizer
Keyword(s):  
Amino Acids ◽  
H2o2 Oxidation ◽  
Cyclic Amino Acids

scholarly journals Synthesis of new Cα-tetrasubstituted α-amino acids

2009 ◽  
Vol 5 ◽  
Author(s):  
Andreas A Grauer ◽  
Burkhard König
Keyword(s):  
Amino Acids ◽  
Secondary Structure ◽  
Aromatic Aldehydes ◽  
Building Blocks ◽  
Reaction Conditions ◽  
Peptide Backbone ◽  
Aliphatic Aldehydes ◽  
New Class ◽  
Cyclic Amino Acids

Cα-Tetrasubstituted α-amino acids are important building blocks for the synthesis of peptidemimetics with stabilized secondary structure, because of their ability to rigidify the peptide backbone. Recently our group reported a new class of cyclic Cα-tetrasubstituted tetrahydrofuran α-amino acids prepared from methionine and aromatic aldehydes. We now report the extension of this methodology to aliphatic aldehydes. Although such aldehydes are prone to give aldol products under the reaction conditions used, we were able to obtain the target cyclic amino acids in low to moderate yields and in some cases with good diastereoselectivity.

New reaction involving the detritylation of N-trityl-substituted cyclic amino acids

1984 ◽  
Vol 20 (5) ◽  
pp. 576-576
Author(s):  
A. V. Eremeev ◽  
F. D. Polyak ◽  
�. �. Liepin'sh
Keyword(s):  
Amino Acids ◽  
Cyclic Amino Acids

scholarly journals Sludge char-to-fuel approaches based on the hydrothermal fueling IV: fermentation

2021 ◽  
Author(s):  
Jinyi Qin ◽  
Rui Zhang ◽  
Ruiwen Yang ◽  
Jiao Fang ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Organic Matter ◽  
Fatty Acid ◽  
Sewage Sludge ◽  
Acid Content ◽  
Saturated Fatty Acids ◽  
Fatty Acid Content ◽  
Heating Value ◽  
Cyclic Amino Acids

Abstract Sewage sludge was subjected to hydrothermal fueling (HTF) (330 °C for 40 min), obtaining hydrochar at 13.5 MJ kg−1. The higher heating value (HHV) of the raw sludge was related to its fatty acid content. The results showed that although the higher heating value (HHV) of the raw sludge was related to its fatty acid content, with the intensification of HTF, the increase in aliphatic/cyclic amino acids determined the production of HHV in the hydrochar. In order to increase the content of fatty acids and amino acids, the sludge was fermented. However, the Bacteroidetes consumed the organic matter too early, which was detrimental to the production of HHV. Therefore, appropriate sludge fermentation is recommended to restrict excessive Bacteroidetes proliferation, decompose lipids to saturated fatty acids, and convert proteins to aliphatic/cyclic amino acids to increase the efficiency of converting sludge to fuel.

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