The Quest for Carbenic Nitrile Imines: Experimental and Computational Characterization ofC-Amino Nitrile Imine

2015 ◽  
Vol 2015 (34) ◽  
pp. 7484-7493 ◽  
Author(s):  
Cláudio M. Nunes ◽  
Igor Reva ◽  
Mário T. S. Rosado ◽  
Rui Fausto
Keyword(s):  
Nitrile Imine ◽  
Nitrile Imines ◽  
Amino Nitrile

Photoisomerization-enhanced 1,3-dipolar cycloaddition of carbon-bridged octocyclic azobenzene with photo-released nitrile imine for peptide stapling and imaging in live cells

2020 ◽  
Vol 18 (29) ◽  
pp. 5602-5607
Author(s):  
Jiajie Deng ◽  
Xueting Wu ◽  
Guiling Guo ◽  
Xiaohu Zhao ◽  
Zhipeng Yu
Keyword(s):  
Cell Apoptosis ◽  
Live Cells ◽  
Dipolar Cycloaddition ◽  
Ligation Reaction ◽  
Nitrile Imine ◽  
Nitrile Imines ◽  
Peptide Stapling

A novel photo-click ligation reaction between nitrile imines and photo-switchable octocyclic azobenzenes was established to both tune the conformation of the NoxaB peptide and conjugate probes with enhanced efficacy in cell apoptosis.

scholarly journals Metal-free C–C bond formation via coupling of nitrile imines and boronic acids

2019 ◽  
Vol 10 (44) ◽  
pp. 10412-10416 ◽  
Author(s):  
Keith Livingstone ◽  
Sophie Bertrand ◽  
Jenna Mowat ◽  
Craig Jamieson
Keyword(s):  
Boronic Acid ◽  
Bond Formation ◽  
Boronic Acids ◽  
Transition Metal Catalysis ◽  
Subsequent Reaction ◽  
Metal Catalysis ◽  
Photochemical Generation ◽  
Nitrile Imine ◽  
Nitrile Imines ◽  
Boronic Acid Derivatives

Photochemical generation of nitrile imine species and subsequent reaction with boronic acid derivatives furnishes a new C–C bond without transition metal catalysis.

π-Facial Selectivity in 1,3-Dipolar Cycloaddition Reactions of α-Methylidene-γ-lactone Substituted by 4-Methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl Group in γ-Position

2002 ◽  
Vol 67 (3) ◽  
pp. 353-364 ◽  
Author(s):  
Petr Melša ◽  
Ctibor Mazal
Keyword(s):  
Double Bond ◽  
Carboxylic Acid ◽  
Nitrile Oxide ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Enantiomerically Pure ◽  
Nitrile Imine ◽  
Facial Selectivity ◽  
Excellent Selectivity

Diastereoselectivity of 1,3-dipolar cycloaddition reactions of benzyl azide, diazomethane, a nitrile oxide and a nitrile imine to α-methylidene-γ-lactone dipolarophile was effectively controlled by a bulky γ-substituent, 4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl in γ-position of the dipolarophile. The dipoles added from the less hindered face of the double bond with an excellent selectivity. Enantiomerically pure dipolarophile was prepared from the easily available (S)-5-oxotetrahydrohydrofuran-2-carboxylic acid.

Back Cover: Understanding Reactivity Patterns in Light-Induced Nitrile Imine Mediated Tetrazole-Ene Cycloadditions (ChemPhotoChem 5/2017)

ChemPhotoChem ◽  
2017 ◽  
Vol 1 (5) ◽  
pp. 253-253
Author(s):  
Eva Blasco ◽  
Yuuki Sugawara ◽  
Paul Lederhose ◽  
James P. Blinco ◽  
Anne-Marie Kelterer ◽  
...  
Keyword(s):  
Back Cover ◽  
Nitrile Imine

The regioselectivity in the formation of pyrazolines and pyrazoles from nitrile imines

1984 ◽  
Vol 21 (4) ◽  
pp. 1013-1016 ◽  
Author(s):  
Hamdi M. Hassaneen ◽  
Rifaat H. Hilal ◽  
Nehal M. Elwan ◽  
Abdelhamid Harhash ◽  
Ahmad S. Shawali
Keyword(s):  
Nitrile Imines
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