Intra-Intermolecular Palladium-Catalyzed Domino Reactions of Glycine Allylamides for the Synthesis of Diversely Functionalized Piperazinones

2015 ◽  
Vol 2015 (19) ◽  
pp. 4261-4268 ◽  
Author(s):  
Gianluigi Broggini ◽  
Egle M. Beccalli ◽  
Tea Borelli ◽  
Filippo Brusa ◽  
Silvia Gazzola ◽  
...  
Keyword(s):  
Domino Reactions ◽  
Palladium Catalyzed

The Virtue of Palladium-Catalyzed Domino Reactions − Diverse Oligocyclizations of Acyclic 2-Bromoenynes and 2-Bromoenediynes

2005 ◽  
Vol 38 (5) ◽  
pp. 413-422 ◽  
Author(s):  
Armin de Meijere ◽  
Paultheo von Zezschwitz ◽  
Stefan Bräse
Keyword(s):  
Domino Reactions ◽  
Palladium Catalyzed

ChemInform Abstract: Tunable Di- and Mono-γ-C-H Arylation of Phenylacetamides by Palladium-Catalyzed Domino Reactions.

ChemInform ◽  
2016 ◽  
Vol 47 (35) ◽  
Author(s):  
Yunyun Liu ◽  
Bin Huang ◽  
Xiaoji Cao ◽  
Jie-Ping Wan
Keyword(s):  
Domino Reactions ◽  
Palladium Catalyzed

Tunable Di- and Mono-γ-C−H Arylation of Phenylacetamides by Palladium-Catalyzed Domino Reactions

ChemCatChem ◽  
2016 ◽  
Vol 8 (8) ◽  
pp. 1470-1473 ◽  
Author(s):  
Yunyun Liu ◽  
Bin Huang ◽  
Xiaoji Cao ◽  
Jie-Ping Wan
Keyword(s):  
Domino Reactions ◽  
Palladium Catalyzed

Stereoselective Synthesis of 3-Alkylideneoxindoles via Palladium-Catalyzed Domino Reactions†

2005 ◽  
Vol 70 (17) ◽  
pp. 6972-6975 ◽  
Author(s):  
Reiko Yanada ◽  
Shingo Obika ◽  
Tsubasa Inokuma ◽  
Kazuo Yanada ◽  
Masayuki Yamashita ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Domino Reactions ◽  
Palladium Catalyzed

Pd-Catalyzed Domino Reactions Involving Alkenes To Access Substituted Indole Derivatives

Synthesis ◽  
2020 ◽  
Vol 52 (19) ◽  
pp. 2731-2760
Author(s):  
Egle M. Beccalli ◽  
Michael S. Christodoulou ◽  
Francesca Foschi ◽  
Sabrina Giofrè
Keyword(s):  
Double Bond ◽  
The Other ◽  
Indole Derivatives ◽  
Domino Reactions ◽  
Recent Advances ◽  
Other Hand ◽  
Palladium Catalyzed ◽  
Intermolecular Reactions

Palladium-catalyzed domino reactions are advanced tools in achieving various nitrogen-containing heterocycles in an efficient and economical manner due to the reduced number of steps in the process. This review highlights recent advances in domino processes aimed at the synthesis of indole derivatives and polycyclic systems containing the indole nucleus in intra/intra- or intra/intermolecular reactions. In particular, we consider domino processes that involve a double bond in a step of the sequence, which allow the issue of regioselectivity in the cyclization to be faced and overcome. The different sections in this review focus on the synthesis of the indole nucleus and functionalization of the scaffold starting from different substrates that have been identified as activated starting materials, which involve a halogenated moiety or unactivated unsaturated systems. In the former case, the reaction is under Pd(0) catalysis, and in the second case a Pd(II) catalytic species is required and then an oxidant is necessary to reconvert the Pd(0) into the active Pd(II) species. On the other hand, the second method has the advantage that it uses easy available and inexpensive substrates.1 Introduction2 Indole Scaffold Synthesis2.1 Activated Substrates2.2 Unactivated Substrates3 Functionalization of Indole Scaffold3.1 Activated Substrates3.2 Unactivated Substrates4 Conclusions

Understanding Sulfone Behavior in Palladium-Catalyzed Domino Reactions with Aryl Iodides

2006 ◽  
Vol 12 (17) ◽  
pp. 4576-4583 ◽  
Author(s):  
Inés Alonso ◽  
Manuel Alcamí ◽  
Pablo Mauleón ◽  
Juan C. Carretero
Keyword(s):  
Domino Reactions ◽  
Aryl Iodides ◽  
Palladium Catalyzed
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