One-Pot Chemoselective Bis(Suzuki-Miyaura Cross-Coupling): Efficient Access to 3,9-Bis[(hetero)aryl]-4H-pyrido[1,2-a]pyrimidin-4-one Derivatives Under Microwave Irradiation

2012 ◽  
Vol 2012 (28) ◽  
pp. 5595-5604 ◽  
Author(s):  
Youssef Kabri ◽  
Maxime D. Crozet ◽  
Nicolas Primas ◽  
Patrice Vanelle
Keyword(s):  
Microwave Irradiation ◽  
Cross Coupling ◽  
One Pot ◽  
Efficient Access

One-pot Synthesis of Dibenzofurans via SNAr and Subsequent Ligand-free Palladium-catalyzed Intramolecular Aryl-aryl Cross-coupling Reactions under Microwave Irradiation

2011 ◽  
Vol 66 (8) ◽  
pp. 833-836
Author(s):  
Zhiping Che ◽  
Hui Xu
Keyword(s):  
Microwave Irradiation ◽  
Cross Coupling ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Cross Coupling Reactions ◽  
Ligand Free ◽  
Palladium Catalyzed ◽  
Snar Reaction

An efficient one-pot synthesis of dibenzofurans, via SNAr reaction of aryl halides and ortho-bromophenols in the presence of anhydrous K2CO3 and subsequent ligand-free palladium-catalyzed intramolecular aryl-aryl cross-coupling cyclization under microwave irradiation, is described.

Iron-Catalysed Regioselective Arylsulfonylation of Quinoline N-Oxides with Sodium Arylsulfinates under Microwave Irradiation

2017 ◽  
Vol 41 (12) ◽  
pp. 705-708 ◽  
Author(s):  
Wenpeng Mai ◽  
Mingxiu Lv ◽  
Xiaofeng Zhang ◽  
Kui Lu
Keyword(s):  
Microwave Irradiation ◽  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Regioselective Synthesis ◽  
One Pot ◽  
Cross Coupling Reaction

An efficient protocol for one-pot deoxygenative and regioselective synthesis of 2-arylsulfonylquinolines has been developed via iron-catalysed cross-coupling reaction of quinoline N-oxides with sodium arylsulfinates in moderate to good yields under microwave irradiation. The reactions proceeded over a broad range of substrates with good regioselectivity and functional group tolerance.

scholarly journals One-pot borylation/Suzuki–Miyaura sp2–sp3 cross-coupling

2017 ◽  
Vol 53 (67) ◽  
pp. 9364-9367 ◽  
Author(s):  
Luke Whitaker ◽  
Hassan Y. Harb ◽  
Alexander P. Pulis
Keyword(s):  
Carbonyl Compounds ◽  
Cross Coupling ◽  
One Pot ◽  
Efficient Access

One-pot borylation/Suzuki–Miyaura sp2–sp3 cross coupling allows efficient access to important diaryl methanes, allyl aryls and α-arylated carbonyl compounds.

Efficient Access to Original 6-Substituted 5-Nitro-2,3-dihydro­imidazo[2,1-b]oxazoles

Synthesis ◽  
2017 ◽  
Vol 49 (12) ◽  
pp. 2775-2785 ◽  
Author(s):  
Fanny Mathias ◽  
Youssef Kabri ◽  
Maxime Crozet ◽  
Patrice Vanelle
Keyword(s):  
Intramolecular Cyclization ◽  
Bromine Atom ◽  
Cross Coupling ◽  
Sonogashira Reaction ◽  
Coupling Reactions ◽  
One Pot ◽  
Cross Coupling Reactions ◽  
Efficient Access ◽  
Palladium Catalyzed ◽  
Hydroxyethyl Group

A one-pot sequential intramolecular cyclization and Suzuki–Miyaura or Sonogashira reaction under microwave irradiation are reported in the 5-nitro-2,3-dihydroimidazo[2,1-b]oxazole series. The intramolecular cyclization of 1-(2,4-dibromo-5-nitro-1H-imidazol-1-yl)propan-2-ol between the hydroxyethyl group and the bromine atom at the 2-position is carried out first, followed by optimization and generalization of the Suzuki–Miyaura and Sonogashira cross-coupling reactions of the bromine atom at the 4-position. The various boronic acids and alkynyl derivatives used to perform these palladium-catalyzed cross-coupling reactions allowed to substitute the 6-position of 5-nitro-2,3-dihydroimidazo[2,1-b]oxazole compounds.

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