A One-Pot, Three-Component Approach to Functionalised Tetrahydroisoquinolines Using Domino Heck-aza-Michael Reactions

2011 ◽  
Vol 2011 (9) ◽  
pp. 1632-1635 ◽  
Author(s):  
Daniel L. Priebbenow ◽  
Frederick M. Pfeffer ◽  
Scott G. Stewart
Keyword(s):  
One Pot ◽  
Michael Reactions ◽  
Component Approach

ChemInform Abstract: A One-Pot, Three-Component Approach to Functionalized Tetrahydroisoquinolines Using Domino Heck-aza-Michael Reactions.

ChemInform ◽  
2011 ◽  
Vol 42 (28) ◽  
pp. no-no
Author(s):  
Daniel L. Priebbenow ◽  
Frederick M. Pfeffer ◽  
Scott G. Stewart
Keyword(s):  
One Pot ◽  
Michael Reactions ◽  
Component Approach

A new more atom-efficient multi-component approach to tetrasubstituted imidazoles: one-pot condensation of nitriles, amines and benzoin

RSC Advances ◽  
2016 ◽  
Vol 6 (71) ◽  
pp. 67281-67289 ◽  
Author(s):  
Ali Khalafi-Nezhad ◽  
Mohsen Shekouhy ◽  
Hashem Sharghi ◽  
Jasem Aboonajmi ◽  
Abdolkarim Zare
Keyword(s):  
Primary Amines ◽  
One Pot ◽  
One Pot Condensation ◽  
Component Approach ◽  
The One ◽  
Tetrasubstituted Imidazoles

A new more atom-efficient multi-component approach for the synthesis of tetrasubstituted imidazoles via the one-pot condensation of nitriles, primary amines and benzoin has been described.

Copper-Catalyzed Tandem Multi-Component Approach to 1,3-Oxazines at Room Temperature by Cross-Dehydrogenative Coupling Using Methanol as C1 Feedstock

Synlett ◽  
2018 ◽  
Vol 29 (09) ◽  
pp. 1171-1175 ◽  
Author(s):  
Paran Borpatra ◽  
Mohit Deb ◽  
Pranjal Baruah
Keyword(s):  
Carbon Source ◽  
Room Temperature ◽  
Inert Atmosphere ◽  
Environmentally Benign ◽  
Metal Catalyst ◽  
Methylene Carbon ◽  
One Pot ◽  
Dehydrogenative Coupling ◽  
Tert Butyl Hydroperoxide ◽  
Component Approach

A copper(II)-catalyzed multi-component one-pot approach for the synthesis of 1,3-oxazines at room temperature is reported here. Methanol is used as the solvent as well as the carbon source. The methylene carbon of the oxazine product comes from methanol via formaldehyde. tert-Butyl hydroperoxide is used as the oxidant. The reaction uses an environmentally benign metal catalyst and oxidant. No inert atmosphere or precaution is required for the reaction. Most importantly, the reaction avoids the use of carcinogenic formaldehyde.

On the Necessity of One-Pot Tautomer Trapping in Asymmetric Michael Reactions of Arylideneisoxazol-5-ones

2020 ◽  
Vol 2020 (15) ◽  
pp. 2264-2270 ◽  
Author(s):  
Antonio Macchia ◽  
Valentina Dafnae Cuomo ◽  
Antonia Di Mola ◽  
Giovanni Pierri ◽  
Consiglia Tedesco ◽  
...  
Keyword(s):  
One Pot ◽  
Michael Reactions

Green Three-component Synthesis of Merocyanin Dyes Based on 4- Arylideneisoxazol-5(4H)-ones

2020 ◽  
Vol 7 (2) ◽  
pp. 217-225
Author(s):  
Fatemeh K. Damghani ◽  
Hamzeh Kiyani ◽  
Seied A. Pourmousavi
Keyword(s):  
Green Chemistry ◽  
Aqueous Medium ◽  
Room Temperature ◽  
Choline Chloride ◽  
Energy Sources ◽  
One Pot ◽  
Ultrasound Waves ◽  
Simple Preparation ◽  
Three Component Reaction ◽  
Component Approach

A one-pot three-component reaction promoted by choline chloride: zinc(II) chloride deepeutectic solvent (ChCl-ZnCl2 DES) in an aqueous medium for the synthesis of several merocyanin dyes based on isoxazol-5(4H)-ones is presented. This three-component approach is efficient, clean, experimentally simple, convenient, safe, and environmentally friendly. This reaction was performed at room temperature without using energy sources such as heat, microwave and ultrasound waves. Nonuse of toxic solvents, available materials, one-vessel, no wasted reagents, simple preparation, and recyclability of DES are other important points of this method that is significant from the perspective of green chemistry.

Phosphite-Mediated Synthesis of Benzimidazoles: A One-Pot Four-Component Approach from Nitrophenols

2011 ◽  
Vol 2011 (31) ◽  
pp. 6177-6180 ◽  
Author(s):  
Laurent El Kaïm ◽  
Laurence Grimaud ◽  
Srinivas Reddy Purumandla
Keyword(s):  
One Pot ◽  
Component Approach

A one-pot three-component approach to synthesis of novel dihydroxyoxoindeno[1,2- b ]pyrrole derivatives

2018 ◽  
Vol 59 (9) ◽  
pp. 818-822 ◽  
Author(s):  
Fatemeh Rahimi ◽  
Hajar Hosseini ◽  
Mohammad Bayat
Keyword(s):  
One Pot ◽  
Pyrrole Derivatives ◽  
Component Approach
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