The Reaction of Carboxylic Acid Esters with RfMgBr: A Convenient Synthesis of Perfluoroalkyl Ketones

2010 ◽  
Vol 2010 (36) ◽  
pp. 7012-7019 ◽  
Author(s):  
Can Xue ◽  
Guangke He ◽  
Chunling Fu ◽  
Liqin Xue ◽  
Zhenyang Lin ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Convenient Synthesis ◽  
Acid Esters

scholarly journals Alkoxide-induced ring opening of bicyclic 2-vinylcyclobutanones: A convenient synthesis of 2-vinyl-substituted 3-cycloalkene-1-carboxylic acid esters

2012 ◽  
Vol 8 ◽  
pp. 650-657 ◽  
Author(s):  
Xiufang Ji ◽  
Zhiming Li ◽  
Quanrui Wang ◽  
Andreas Goeke
Keyword(s):  
Carboxylic Acid ◽  
Ring Opening ◽  
Claisen Rearrangement ◽  
Ring Cleavage ◽  
Unsaturated Ester ◽  
Supplementary Method ◽  
Convenient Synthesis ◽  
High Yields ◽  
Acid Esters

The fused 2-vinyl or 2-phenyl substituted cyclobutanones 4 undergo stereoselective ring openings by the action of alkoxide ions (t-BuO− or MeO−) to produce novel vicinally disubstituted cycloalkene derivatives 5 and 6 in moderate to high yields. The ring cleavage usually occurs with complete regioselectivity. The accessibility of γ,δ-unsaturated ester or acid derivatives makes this transformation a good supplementary method for the well-established Johnson–Claisen rearrangement.

scholarly journals A CONVENIENT SYNTHESIS AND CYTOTOXIC ACTIVITY OF 3-ARYL-5-PENTYL-1,2,4-OXADIAZOLES FROM CARBOXYLIC ACID ESTERS AND ARYLAMIDOXIMES UNDER SOLVENT-FREE CONDITIONS

2014 ◽  
Vol 59 (1) ◽  
pp. 2359-2362 ◽  
Author(s):  
CARLOS JONNATAN PIMENTEL BARROS ◽  
ZILYANE CARDOSO DE SOUZA ◽  
JUCLEITON JOSÉRUFINO DE FREITAS ◽  
PAULO BRUNO NORBERTO DA SILVA ◽  
GARDENIA CARMEN GADELHA MILITÃO ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Cytotoxic Activity ◽  
Solvent Free ◽  
Convenient Synthesis ◽  
Solvent Free Conditions ◽  
Acid Esters

ChemInform Abstract: The Reaction of Carboxylic Acid Esters with RfMgBr: A Convenient Synthesis of Perfluoroalkyl Ketones.

ChemInform ◽  
2011 ◽  
Vol 42 (18) ◽  
pp. no-no
Author(s):  
Can Xue ◽  
Guangke He ◽  
Chunling Fu ◽  
Liqin Xue ◽  
Zhengyan Lin ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Convenient Synthesis ◽  
Acid Esters

Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters

2019 ◽  
Author(s):  
Jiang Wang ◽  
Brian P. Cary ◽  
Peyton Beyer ◽  
Samuel H. Gellman ◽  
Daniel Weix
Keyword(s):  
Carboxylic Acid ◽  
Solid Support ◽  
Reaction Conditions ◽  
Decarboxylative Coupling ◽  
New Strategy ◽  
The Cross ◽  
Acyl Donors ◽  
Acid Esters

A new strategy for the synthesis of ketones is presented based upon the decarboxylative coupling of N-hydroxyphthalimide (NHP) esters with S-2-pyridyl thioesters. The reactions are selective for the cross-coupled product because NHP esters act as radical donors and the thioesters act as acyl donors. The reaction conditions are general and mild, with over 40 examples presented, including larger fragments and the 20-mer peptide Exendin(9-39) on solid support.

ChemInform Abstract: Practical Syntheses of Functionalized 1-Oxo-1,2,3,4-tetrahydro-β- carboline-3-carboxylic Acid Esters.

ChemInform ◽  
2010 ◽  
Vol 27 (33) ◽  
pp. no-no
Author(s):  
L. JEANNIN ◽  
J. SAPI ◽  
E. VASSILEVA ◽  
P. RENARD ◽  
J.-Y. LARONZE
Keyword(s):  
Carboxylic Acid ◽  
Acid Esters

Synthesis of Ethers by GaBr3-Catalyzed Reduction of Carboxylic Acid Esters and Lactones by Siloxanes

ChemSusChem ◽  
2013 ◽  
Vol 7 (2) ◽  
pp. 644-649 ◽  
Author(s):  
Ursula Biermann ◽  
Jürgen O. Metzger
Keyword(s):  
Carboxylic Acid ◽  
Acid Esters

Preparation of unsaturated carboxylic acid esters with metallosilicate catalysts

Zeolites ◽  
1995 ◽  
Vol 15 (1) ◽  
pp. 84
Author(s):  
H. Nakajima ◽  
T. Fujii ◽  
K. Kitagawa
Keyword(s):  
Carboxylic Acid ◽  
Unsaturated Carboxylic Acid ◽  
Acid Esters

6-Methylergoline-8-carboxylic acid esters as serotonin antagonists: N1-substituent effects on 5HT2 receptor affinity

1987 ◽  
Vol 30 (10) ◽  
pp. 1823-1826 ◽  
Author(s):  
Gifford Marzoni ◽  
William L. Garbrecht ◽  
Pawel Fludzinski ◽  
Marlene L. Cohen
Keyword(s):  
Carboxylic Acid ◽  
Substituent Effects ◽  
Serotonin Antagonists ◽  
Receptor Affinity ◽  
5Ht2 Receptor ◽  
Acid Esters
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