Palladium-Catalyzed Bis-Functionalization of Isatylidenes: A Facile Route towards Spiro-Indol-2-ones

2010 ◽  
Vol 2010 (28) ◽  
pp. 5489-5497 ◽  
Author(s):  
Sholly Clair George ◽  
Jubi John ◽  
Saithalavi Anas ◽  
Joshni John ◽  
Yoshinori Yamamoto ◽  
...  
2014 ◽  
Vol 10 ◽  
pp. 1462-1470 ◽  
Author(s):  
Jubi John ◽  
Eliza Târcoveanu ◽  
Peter G Jones ◽  
Henning Hopf

A facile route towards highly functionalized 3(2H)-furanones via a sequential Mannich addition–palladium catalyzed ring closing has been elaborated. The reaction of 4-chloroacetoacetate esters with imines derived from aliphatic and aromatic aldehydes under palladium catalysis afforded 4-substituted furanones in good to excellent yields. 4-Hydrazino-3(2H)-furanones could also be synthesized from diazo esters in excellent yields by utilising the developed strategy. We could also efficiently transform the substituted furanones to aza-prostaglandin analogues.


2014 ◽  
Vol 12 (31) ◽  
pp. 5861-5865 ◽  
Author(s):  
Xiaolin Pan ◽  
Yong Luo ◽  
Yunyan Kuang ◽  
Guangming Li

A tandem reaction catalyzed by palladium is developed to provide a facile and simple route for the synthesis of 5-methyl-5H-indeno[1,2-c]quinolones.


1985 ◽  
Vol 16 (19) ◽  
Author(s):  
B. AKERMARK ◽  
J.-E. NYSTROEM ◽  
T. REIN ◽  
J.-E. BAECKVALL ◽  
P. HELQUIST ◽  
...  

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