Guanidine-Catalyzed Asymmetric Synthesis of 2,2-Disubstituted Chromane Skeletons by Intramolecular Oxa-Michael Addition

2008 ◽  
Vol 2008 (16) ◽  
pp. 2759-2766 ◽  
Author(s):  
Noriko Saito ◽  
Akemi Ryoda ◽  
Waka Nakanishi ◽  
Takuya Kumamoto ◽  
Tsutomu Ishikawa
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Addition

Asymmetric Synthesis of an Amino Acid Derivative from Achiral Aroyl Acrylamide by Reversible Michael Addition and Preferential Crystallization

2016 ◽  
Vol 22 (46) ◽  
pp. 16429-16432 ◽  
Author(s):  
Yuki Kaji ◽  
Naohiro Uemura ◽  
Yoshio Kasashima ◽  
Hiroki Ishikawa ◽  
Yasushi Yoshida ◽  
...  
Keyword(s):  
Amino Acid ◽  
Asymmetric Synthesis ◽  
Acid Derivative ◽  
Michael Addition ◽  
Amino Acid Derivative

Asymmetric synthesis of highly functionalized spirothiazolidinone tetrahydroquinolines via a squaramide-catalyzed cascade reaction

2018 ◽  
Vol 16 (48) ◽  
pp. 9390-9401 ◽  
Author(s):  
Yong-Xing Song ◽  
Da-Ming Du
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Addition ◽  
Addition Reaction ◽  
Cascade Reaction ◽  
Michael Addition Reaction

A bifunctional squaramide-catalyzed asymmetric cascade aza-Michael/Michael addition reaction for the synthesis of chiral spirothiazolidinone tetrahydroquinolines with three contiguous stereocenters has been developed.

Enantioselective vinylogous Michael addition of β,γ-unsaturated butenolide to 2-iminochromenes

2019 ◽  
Vol 43 (25) ◽  
pp. 9771-9775 ◽  
Author(s):  
Vijay Gupta ◽  
Ravi P. Singh
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Addition

An efficient organocatalyzed asymmetric synthesis of 2-amino-4H-(2-furanone)-3-carbonitrile via vinylogous Michael addition of non-activated β,γ-unsaturated butenolide to 2-iminochromenes has been realized.

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