Enzyme Mimics for Michael Additions with Novel Proton Transport Groups

2008 ◽  
Vol 2008 (14) ◽  
pp. 2397-2403 ◽  
Author(s):  
Luis Simón ◽  
Francisco M. Muñiz ◽  
Silvia Sáez ◽  
César Raposo ◽  
Joaquín R. Morán
1992 ◽  
Vol 86 (1) ◽  
pp. 63-70 ◽  
Author(s):  
David Brauer ◽  
DeNea Conner ◽  
Shu-I Tu

2020 ◽  
Vol 24 (7) ◽  
pp. 746-773
Author(s):  
Péter Bakó ◽  
Tamás Nemcsok ◽  
Zsolt Rapi ◽  
György Keglevich

: Many catalysts were tested in asymmetric Michael additions in order to synthesize enantioenriched products. One of the most common reaction types among the Michael reactions is the conjugated addition of malonates to enones making it possible to investigate the structure–activity relationship of the catalysts. The most commonly used Michael acceptors are chalcone, substituted chalcones, chalcone derivatives, cyclic enones, while typical donors may be dimethyl, diethyl, dipropyl, diisopropyl, dibutyl, di-tert-butyl and dibenzyl malonates. This review summarizes the most important enantioselective catalysts applied in these types of reactions.


1971 ◽  
Vol 246 (19) ◽  
pp. 6024-6028 ◽  
Author(s):  
Peter C. Hinkle ◽  
Lawrence L. Horstman

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