Diastereoselective 1,3-Dipolar Cycloaddition Reactions between Azomethine Ylides and Chiral Acrylates Derived from Methyl (S)- and (R)-Lactate – Synthesis of Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors

2007 ◽  
Vol 2007 (30) ◽  
pp. 5038-5049 ◽  
Author(s):  
Carmen Nájera ◽  
M. de Gracia Retamosa ◽  
José M. Sansano ◽  
Abel de Cózar ◽  
Fernando P. Cossío
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rna Polymerase ◽  
Azomethine Ylides ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Hepatitis C Virus Rna ◽  
Rna Dependent Rna Polymerase ◽  
Polymerase Inhibitors ◽  
Virus Rna

B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase

2014 ◽  
Vol 80 ◽  
pp. 579-592 ◽  
Author(s):  
Amel Meguellati ◽  
Abdelhakim Ahmed-Belkacem ◽  
Wei Yi ◽  
Romain Haudecoeur ◽  
Marie Crouillère ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rna Polymerase ◽  
Hepatitis C Virus Rna ◽  
Allosteric Inhibitors ◽  
Rna Dependent Rna Polymerase ◽  
Virus Rna

Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase

Virology ◽  
2019 ◽  
Vol 529 ◽  
pp. 226-233 ◽  
Author(s):  
Ryosuke Suzuki ◽  
Mami Matsuda ◽  
Takashi Shimoike ◽  
Koichi Watashi ◽  
Hideki Aizaki ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Protein Kinase ◽  
Rna Polymerase ◽  
Protein Kinase R ◽  
Hepatitis C Virus Rna ◽  
Rna Dependent Rna Polymerase ◽  
Virus Rna
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