Fat-Derived Aziridines and Their N-Substituted Derivatives: Biologically Active Compounds Based on Renewable Raw Materials

2003 ◽  
Vol 2003 (4) ◽  
pp. 649-659 ◽  
Author(s):  
Sandra Fürmeier ◽  
Jürgen O. Metzger
Keyword(s):  
Raw Materials ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Renewable Raw Materials

scholarly journals Analysis of the range of preparations with raw materials Pinus Sp. and products of its processing

2020 ◽  
Vol 3 (2) ◽  
pp. 61-66
Author(s):  
N.Ye. Stadnytska ◽  
◽  
A.O. Kyrychuk ◽  
O.M. Fedorushyn ◽  
G.M. Shyjan ◽  
...  
Keyword(s):  
Pharmaceutical Company ◽  
Raw Materials ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
The City ◽  
Pharmaceutical Enterprises

The analysis of the range of drugs containing raw materials and biologically active compounds Pinus sp. registered in Ukraine and found: most drugs are presented in the form of ointments; the predominant share of the range (79%) of the studied drugs are multicomponent drugs; the share of the range of drugs manufactured at pharmaceutical enterprises of Ukraine is 38%; the largest number of drugs is manufactured by domestic manufacturers in the city of Zhytomyr PJSC "Liktravy" and LLC "DKP" Pharmaceutical Company; among importing countries, Germany dominates, followed by India and Estonia, respectively.

scholarly journals Diversity of Eleutherococcus genus in respect of biologically active compounds accumulation

2014 ◽  
Vol 60 (3) ◽  
pp. 34-43 ◽  
Author(s):  
Katarzyna Bączek
Keyword(s):  
High Performance Liquid Chromatography ◽  
Phenolic Acids ◽  
High Performance ◽  
Raw Materials ◽  
Stem Bark ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Eleutheroside B

Summary Eight species of Eleutherococcus genus grown at Rogów Arboretum collection were compared in respect of biologically active compounds accumulation, i.e. eleutheroside B and E, phenolic acids and sterols. For the determination of content of these compounds in underground organs and stem bark high performance liquid chromatography was applied. The highest content of the sum of eleutherosides B and E was observed in underground organs and stem bark of E. leucorrhizus (322.0 and 300.8 mg × 100 g-1, respectively) and E. nodiflorus (218.9 and 363.5 mg × 100g-1, respectively). In the raw materials from E. senticosus, the content of these compounds was significantly lower (177.4 and 159.3 mg × 100 g-1, respectively). E divaricatus and E. setchuenensis were characterized by the lowest accumulation of these compounds in underground organs whereas E. divaricatus, E. sessiliflorus and E. giraldii - in stem bark. Four phenolic acids were identified in the investigated species, namely: chlorogenic, rosmarinic, ferulic and caffeic acids. The main phenolic acid in the analyzed species was chlorogenic acid. The content of this compound in underground organs varied from 102.1 (E. henryi) to 958.7 mg × 100 g-1 (E. leucorrhizus) and in stem bark from 26.7 (E. giraldii) to 542.5 mg × 100 g-1 (E. setchuenensis). The content of identified sterol compounds (sitosterol 3-O-β-D-glucoside /eleutheroside A / campesterol, stigmasterol) was relatively low, but higher in underground organs in comparison with stem bark.

scholarly journals Lonicera caerulea L. as a Source of Biologically Active Compounds for the Enrichment of Fermented Milk Product

2021 ◽  
Vol 75 (6) ◽  
pp. 449-456
Author(s):  
Dalija Segliņa ◽  
Inta Krasnova ◽  
Sanita Alsiņa
Keyword(s):  
Raw Materials ◽  
Fermented Milk ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Raw Material ◽  
Future Research ◽  
Milk Product ◽  
Lonicera Caerulea ◽  
Active Compounds ◽  
Promising Source

Abstract Lonicera caerulea L., also known as honeysuckle berries, are rich in biologically active compounds, which makes them a valuable raw material for the development of functional foods. The objects of the research were three honeysuckle cultivars (‘Zoluška’, ‘Siņaja Ptica’, ‘Goluboje Vereteno’), four genotypes (No 2A; No 3; No 5; No 8) and kefir, enriched with various amounts (3–10%) of fruit puree. Physical and chemical analyses to determine the qualitative indicators of raw materials and products were performed. The degree of liking of kefir was assessed using sensory analysis: hedonic and line scales. The results obtained showed that among the cultivars the highest content of anthocyanins (1103.5 mg·100 g−1), total phenols (693.3 mg·100 g−1), flavonoids (753.9 mg·100 g−1), and tannins (1.6 mg·100 g−1), were found in ‘Siņaja Ptica’ berries, while among the genotypes, berries of No 8 had the highest concentration of the aforesaid compounds. Both samples also showed the highest antiradical activity: ABTS+• on average by 71.7% and DPPH− by 43.7%. According to the sensory evaluation, kefir with 10% honeysuckle puree was rated the highest. Honeysuckle berries could be used as a promising source of natural anti-oxidants in future research aimed at developing different new products that could meet consumer expectations.

scholarly journals The bio-flavanoid concentrate of Vitis vinifera L. ‘Red Aladasturi’

2019 ◽  
pp. 91-102
Author(s):  
Roland Kopaliani ◽  
Temur Gvinianidze ◽  
Rezo Jabnidze
Keyword(s):  
Antioxidant Activity ◽  
Moisture Content ◽  
Vitis Vinifera ◽  
Raw Materials ◽  
Initial Moisture Content ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Vitis Vinifera L ◽  
Hammer Mill ◽  
Active Compounds

This paper dwells on the uvological characteristics of cultivar Vitis vinifera L. ‘Red Aladasturi’ grape raw materials growing in the viticulture and winemaking zone of Imereti (Georgia), as well as biologically active compounds and antioxidant activity of hydrophilic extracts and liquid concentrates of its solid matters (stone and skin). Research also covered hydrophilic extracts of grape skin and stone thickened by the vacuum of ‘Red Aladasturi’ grapes raw materials, as well as the concentrates produced from their composition. For research, there were used gravimetric, extractive, spectral and chromatographic methods. We processed samples of grapes raw materials according to the following pattern: identifying qualitative indicators of grapes raw materials; passing grapes raw materials through the DMCSI-type grape clustercomb divider; pressing-out the combless must in a basket press and separation of juice; vacuum sublimation drying of juiceless sweet pomace with an initial moisture content of 45–65% to a final moisture content of 9–10%; separation of the ‘Red Aladasturi’ cultivar’s skin and stone dried to the moisture content of 9–10%, using tea sorting machine designed by G. Lominadze; crushing separately the skin and stone in a micro-mill (TP2 Hammer Mill) until the fraction of 50–100 µm. we have blended the obtained grape-stone ethanol and fluid extracts containing 74–75% of solid maters at an equal ratio (1:1:1) and assessed biologically active compounds and antioxidant activity in this composition. It has been established that the bio-flavanoid liquid concentrate ‘Red Aladasturi’ is strong antioxidant  (55.31–57.45%), and one tablespoon or 8–9 ml of it contains 110–127 mg of flavanoids, which is 105–110% of a full day of rations per person per day.

scholarly journals BIOLOGICALLY ACTIVE SYNTHETIC ORGANIC DYES

2017 ◽  
Vol 60 (1) ◽  
pp. 4 ◽  
Author(s):  
Dmitry N. Kuznetsov ◽  
Konstantin I. Kobrakov ◽  
Anna G. Ruchkina ◽  
Galina S. Stankevich
Keyword(s):  
Organic Dyes ◽  
Raw Materials ◽  
Technical Information ◽  
Practical Interest ◽  
Textile Dyes ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Composition Property ◽  
Biocidal Properties

For citation:Kuznetsov D.N., Kobrakov K.I., Ruchkina A.G., Stankevich G.S. Biologically active synthetic organic dyes. Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol. 2017. V. 60. N 1. P. 4-33.This review is based on the publications found in CAS (Chemical Abstracts Service) database available from STN (The Scientific and Technical Information Network) with respect to dyes, and the compounds that can be classified as the dyes molecular variants. The substances were categorised based on the dyes chromophore properties. Special care was taken to determine the “composition - property” profile within the range of structurally similar compounds. An extensive list of literature references is provided to support the review's subject, including the authors’ own studies on the synthesis, properties and applications of coloured biologically active compounds. The view covers the uses of coloured biologically active compounds as textile dyes and the uses in other industries such as medical, agricultural etc. The review is substantially focused on biocidal azo dyes for the reason of the great variety of possible diazo and azo components which are used for the synthesis of dyes to create an abundance of biocidal dyes with a wide scale of colors. Usage of dyes which add expressed biocidal properties to the coloured textile and other materials and make them resistent to physical and chemical agents is a subject of obvious practical interest, as this enables the combination of two manufacturing processes in one step: coloration and special chemical treatment. Moreover, as it appears from the review, biocidal dyes may be used as additives to the primary dye, without affecting the colour of the object being dyed, albeit in quantities sufficient to endow the required biocidal properties. As demonstated by the review, streamlined synthesis of textile dyes exhibiting biocidal properties, which are able to make a material resistent to biodeterioration or add medicinal properties to the material, is hard to accomplish due to the lack of profound understanding of the mode of action of such compounds. However, the available “composition - property” data and the computer-aided screening data of the biological activity of organic compounds allow us to model and synthesise target products with a high degree of confidence. The review doesn’t cover the properties of biocidal dyes derived from natural raw materials.

scholarly journals The Use of Ultrasound in the Extraction of Biologically Active Compounds from Plant Raw Materials, Used or promising for Use in Medicine (Review)

2021 ◽  
Vol 10 (4) ◽  
pp. 96-116
Author(s):  
A. A. Elapov ◽  
N. N. Kuznetsov ◽  
A. I. Marakhova
Keyword(s):  
Raw Materials ◽  
Biologically Active Compounds ◽  
Ultrasonic Extraction ◽  
Biologically Active ◽  
Individual Plant ◽  
Active Components ◽  
Green Technologies ◽  
Excessive Pressure ◽  
Active Compounds ◽  
Plant Raw Materials

Introduction. This review examines the current state of technology for ultrasonic isolation of biologically active components from medicinal vegetal raw materials. The main emphasis is placed on "green" technologies that intensify the processes of isolation of components such as flavonoids.Text. Modern technologies imply the use of combined methods, including, in addition to ultrasound, significant grinding of raw materials before the extraction process, the use of supercritical solvents (liquefied gases) under excessive pressure. The effect of ultrasound power and temperature on the output of the extracted components was also considered.Conclusion. 1. To increase the yield of biologically active compounds from plant raw materials among various physical methods of extraction intensification, the use of ultrasound dominates. 2. Ultrasonic extraction can be divided into several main types: extraction in an ultrasonic bath, the use of submersible ultrasonic emitters, as well as the combination of ultrasonic extraction with additional types of influence. 3. In the literature, examples of the use of ultrasonic extraction for the isolation of phenolic compounds are most fully presented, it being noted that the parameters need to be selected individually for each individual plant. 4. The power of ultrasound and the nature of the extractant can affect the course of oxidative processes in the extract, and such phenomena are characteristic not only for too high capacities, but also for low ones. 5. Ultrasound can significantly increase the yield of biologically active compounds even in aqueous extraction of fresh raw materials. 6. The spectrum of extractants selection for ultrasonic extraction of plant raw materials is quite large. Both organic solvents (ethanol, methanol, ethyl acetate, acetone) and water can be used, as well as mixtures of various extractants.

scholarly journals VALUABLE SPICE-AROMATIC VEGETABLE – MONARDA CITRIODORA L.

2018 ◽  
pp. 57-60
Author(s):  
L. V. Bespalko ◽  
E. V. Pinchuk ◽  
I. T. Ushakova
Keyword(s):  
Raw Materials ◽  
Mineral Wool ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
State Register ◽  
Russian State ◽  
Mona Lisa ◽  
Selection Of ◽  
Artificial Mineral

One of valuable spice-aromatic vegetable of Lamiaceae family is lemony monarda (Monarda citriodora L.) cultivated as nonperennial crop in most of regions of Russian Federation. Information regarding its parentage and biological special aspects are described here in this article. Brief review regarding nutritional quality and pharmaceutical importance as well as description of four cultivars of lemony monarda (which are currently included to Russian State register of selection invention and approved for usage, two of these cultivars Mona Lisa and Simka were selected and cultivated by Federal Scientific Vegetable Center are given here in this article. Main directions for up-to-date selection and application and practical usage of lemony monarda were indicated. In the field of creation of up-to-date vegetable cultivars, one of the main directions is selection of such a cultivars with high content of biologically active compounds for improvement of antioxidative activity and applicability for its cultivation at hydroponic plant with frame area to provide fresh green vegetables for people all year round. Simka cultivar meets requirements mentioned above and can be cultivated at various types of hydroponic plants including horizontal (salad lines, seedling tables) and vertical (multilayer hydroponics) types using natural (drag turf) or artificial (mineral wool blocks) substrates. This article also describes the main elements of technology of cultivation of lemony monarda in the open and protected ground to get green products and seed production. The features of the preparation of raw materials with a high content of biologically active compounds for fresh consumption and as a spicy-aromatic dry seasoning for salads, meat dishes, as a natural preservative and aromatic of jam, tea and other drinks are shown.

scholarly journals Isolasi Jamur Endofit Dari Akar Tumbuhan Seluang Belum (Luvunga sarmentosa (Blume) Kurz.)

2019 ◽  
Vol 6 (1) ◽  
pp. 68
Author(s):  
Nashrul Wathan ◽  
Witiyasti Imaningsih
Keyword(s):  
Endophytic Fungi ◽  
Plant Tissue ◽  
Raw Materials ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Economic Potential ◽  
Active Compounds ◽  
Living Plant

Abstrak             Endofit merupakan mikroorganisme yang sebagian atau seluruh hidupnya berada di dalam jaringan hidup tumbuhan inang, salah satunya dalam akar seluang belum (Luvunga sarmentosa (Blume) Kurz.). Jamur endofit menyimpan potensi ekonomi tak terbatas terutama dalam bidang farmasi dan pertanian sebagai sumber bahan baku obat, enzim dan senyawa aktif biologis. Jamur endofit yang berada dalam akar seluang belum (Luvunga sarmentosa (Blume) Kurz.) telah berhasil diisolasi menggunakan media PDA, hasilnya didapatkan 16 isolat jamur yang perlu diidentifikasi lebih lanjut.  Kata kunci: Saluang belum, Luvunga sarmentosa, jamur endofit, isolat  Abstract Endophytes are microorganisms that part or all of their lives resides in the living plant tissue, one of which is in the roots of seluang belum (Luvunga sarmentosa (Blume) Kurz.). Endophytic fungi have unlimited economic potential especially in the fields of pharmaceuticals and agriculture as a source of medicinal raw materials, enzymes and biologically active compounds. Endophytic fungi that live in the root of seluang belum (Luvunga sarmentosa (Blume) Kurz.) have been successfully isolated using PDA media, the results obtained 16 fungi isolates that need to be identified further. Keywords: Saluang belum, Luvunga sarmentosa, endophytic fungi, isolates

scholarly journals ASSESSMENT OF THE CONTENT OF POLYPHENOLS IN BIOTECHNOLOGICAL RAW MATERIAL IRIS SIBIRICA L. STAR VARIETY IN COMPARISON WITH INTACT PLANTS

2019 ◽  
pp. 239-250 ◽  
Author(s):  
Ekaterina Alekseevna Antipova ◽  
Lyudmila Evdokimovna Kudrikova ◽  
Lyudmila Ivanovn Tikhomirova ◽  
Natalya Grigoryevna Bazarnova ◽  
Marina Yurievna Cheprasova ◽  
...  
Keyword(s):  
Raw Materials ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Raw Material ◽  
Soil Conditions ◽  
Quantitative Composition ◽  
Active Compounds ◽  
Plant Raw Materials ◽  
Intact Plants ◽  
Growing Conditions

Cultivation of plant raw materials in artificial conditions will inevitably lead to a change in the qualitative and quantitative composition of secondary metabolites in comparison with the composition of plants obtained in soil conditions. The study of the metabolic profile of such plants is very important on the one hand for our understanding of temporal (ontogenetic) and spatial changes in the metabolome of plants, on the other hand in the applied plan to obtain an alternative quality medicinal plant raw materials. In this regard, the aim of this study was to study the content of phenolic compounds in biotechnological raw materials Iris sibirica Grade Стерх in comparison with intact plants. As objects of study used plants propagated mikrokanale (regenerants), which were further grown under conditions of hydroponics (hydroponic). Intact plants were harvested in the field at the age of six years. As a result of research in raw materials Iris sibirica Grade Стерх, grown under different conditions, were found following a group of biologically active compound (БАС), corresponding to the genus Iris L.: fenilpropionovoy acid (Komarova and ferulic acid and their derivatives), flavonoids (glycosides of apigenin, apigenin-7-O-glycoside), isoflavones, and phenolic acids (vanillic acid), neytralizuya flavonoids-glycosides (glycosides of kaempferol and apigenin), stilbene. The qualitative composition of biologically active compounds of Iris sibirica Стерх depended on the growing conditions, while the biotechnological raw materials (hydroponic plants) are the closest to intact plants in terms of the content of biologically active compounds.  This allows us to consider the biotechnology of obtaining the raw material Iris sibirica L. based on hydroponic cultivation coupled with the micropropagation in an alternative way.

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