Domino Aza-Claisen/Mannich Cyclization Reaction from a Chiral α-Alkoxy Enamine or Sequential Alkylation of an α-Alkoxy Ester Enolate or Nitrile Anion, Followed by an Intramolecular Wittig Reaction: Two (3+2) Annulation Routes to Homochiral 4-Alkyl-4-hydroxy-2-cyclopentenone Synthesis

2003 ◽  
Vol 2003 (14) ◽  
pp. 2585-2595 ◽  
Author(s):  
Cyrille Kuhn ◽  
Leandros Skaltsounis ◽  
Claude Monneret ◽  
Jean-Claude Florent
Keyword(s):  
Wittig Reaction ◽  
Cyclization Reaction ◽  
Intramolecular Wittig Reaction ◽  
Mannich Cyclization ◽  
Ester Enolate

scholarly journals Stereoselective Synthesis of Tetraalkyl Cyclobutene-1,2,3,4-tetracarboxylates. Synthesis of Tetraalkyl (Z,Z)-Buta-1,3-diene-1,2,3,4-tetracarboxylates

1999 ◽  
Vol 23 (8) ◽  
pp. 512-513
Author(s):  
Issa Yavari ◽  
Farahnaz Nourmohammadian
Keyword(s):  
Ring Opening ◽  
Wittig Reaction ◽  
Stereoselective Synthesis ◽  
Intramolecular Wittig Reaction ◽  
Ring Opening Reactions ◽  
Boiling Toluene

Tetraalkyl cyclobutene-1,2,3,4-tetracarboxylates, prepared by intramolecular Wittig reaction between a vinylphosphonium salt and diethyl 2-oxobutanedioate, undergo electrocyclic ring-opening reactions, in boiling toluene, to produce highly electron-deficient 1,3-dienes.

ChemInform Abstract: SYNTHESIS OF HETEROCYCLES BY AN INTRAMOLECULAR WITTIG REACTION

1980 ◽  
Vol 11 (49) ◽  
Author(s):  
K. NICKISCH ◽  
W. KLOSE ◽  
E. NORDHOFF ◽  
F. BOHLMANN
Keyword(s):  
Wittig Reaction ◽  
Intramolecular Wittig Reaction

Synthesis of 2-Chromanone-fused [3.2.0] Bicycles through a Phosphine-mediated Tandem [3+2] Cyclization/Intramolecular Wittig Reaction

2021 ◽  
Author(s):  
Junfeng Fu ◽  
Ingrid Rakielle Tsapy Takia ◽  
Peng Chen ◽  
Wei Liu ◽  
Chengjun Jiang ◽  
...  
Keyword(s):  
Wittig Reaction ◽  
High Efficiency ◽  
Intramolecular Wittig Reaction ◽  
Tandem Process ◽  
High Yields

A phosphine-mediated tandem [3+2] cyclization/intramolecular Wittig reaction of 3-aroylcoumarin with alkynone is described. The high efficiency of tandem process allows the synthesis of 2-chromanone-fused bicyclo[3.2.0]heptenones in moderate to high yields...

Strategic Exploitation of the Wittig Reaction: Facile Synthesis of Heteroaromatics and Multifunctional Olefins

Synlett ◽  
2018 ◽  
Vol 29 (20) ◽  
pp. 2608-2622 ◽  
Author(s):  
Wenwei Lin ◽  
Praneeth Karanam ◽  
Ganapuram Reddy
Keyword(s):  
Wittig Reaction ◽  
Coumarin Derivatives ◽  
Facile Synthesis ◽  
Diversity Oriented Synthesis ◽  
New Methods ◽  
Intramolecular Wittig Reaction ◽  
New Synthesis ◽  
Wide Range ◽  
Industrial Level ◽  
New Strategies

In this account, our group’s efforts towards exploring new substrates as precursors for the Wittig reaction have been discussed. Several new strategies developed by our group for the generation of requisite ylides for the Wittig reaction are highlighted. The idea behind the development of some chemoselective and diversity-oriented strategies are discussed in detail in a progressive manner. These strategies encompass a wide range of substrates that are employed for the synthesis of an array of heterocycles and multifunctional olefins and present a huge scope for their application on an industrial level.1 Introduction2 Development of New Methods to Effect Intramolecular Wittig Reaction3 Development of a Catalytic Wittig Reaction4 New Synthesis of Bis-Heteroarenes5 Direct β-Acylation of 2-Arylidene-1,3-indandiones6 Doubly Chemoselective Protocol for the Diversity-Oriented Synthesis of Coumarin Derivatives7 Conclusion

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