Antioxidant activity of monooleyl and dioleylp-coumarates in in vitro and biological model systems

2014 ◽  
Vol 116 (4) ◽  
pp. 370-379 ◽  
Author(s):  
Jiankang Wang ◽  
Fereidoon Shahidi
Keyword(s):  
Antioxidant Activity ◽  
Model Systems ◽  
Biological Model

scholarly journals A protein‐centric view of in vitro biological model systems for schizophrenia

Stem Cells ◽  
2021 ◽  
Author(s):  
Abinaya Chandrasekaran ◽  
Pia Jensen ◽  
Fadumo A. Mohamed ◽  
Madeline Lancaster ◽  
Michael E. Benros ◽  
...  
Keyword(s):  
Model Systems ◽  
Biological Model

Estimation of Total Phenolics and Flavonoid Content and In-vitro Antioxidant Activity of Drypetes sepiaria Stem (Wight and Arn.) Pax and K. Hoffm.

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Packia M. ◽  
Daffodil D. ◽  
Tresina S. ◽  
Mohan R.
Keyword(s):  
Antioxidant Activity ◽  
Total Phenolics ◽  
Antioxidant Activities ◽  
Reducing Power ◽  
Model Systems ◽  
Aluminium Chloride ◽  
Total Phenolic ◽  
Ethanol Extracts ◽  
In Vitro Antioxidant Activity

The total phenolics, flavonoids and in vitro antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts of stem of Drypetes sepiaria were determined using various antioxidant model systems viz, DPPH, hydroxyl, superoxide, ABTS and reducing power. Total phenolic content was estimated by Folin-Ciocalteau method. Flavonoids were determined by Aluminium chloride method. The total phenolics and flavonoids contents were found to be 0.81 g 100 g-1 and 1.12g 100 g-1 respectively in the methanol extract. Among the solvent tested, methanol and ethanol extracts of D. sepiaria stem showed potent in vitro antioxidant activities. This investigation explored that D. sepiaria stem is a potential source of natural antioxidant.

Antioxidant activity of adaptogenic plant remedy in model systems in vitro

2019 ◽  
pp. 21-24
Author(s):  
A.A. Toropova ◽  
B.A. Muruev ◽  
Y.G. Razuvaeva ◽  
I.G. Nikolaeva ◽  
A.G. Mondodoyev
Keyword(s):  
Antioxidant Activity ◽  
Model Systems

Enhanced Antioxidant Efficacy of Nano-Encapsulated Protorhus Longifolia Methanol Extract Stabilized with Eudragit

2021 ◽  
pp. 2150017
Author(s):  
Zimbili Mkhize ◽  
Pule Silent Seboletswe ◽  
Hugues Kamdem Paumo ◽  
Pone Kamdem Boniface ◽  
Lebogang Maureen Katata-Seru
Keyword(s):  
Antioxidant Activity ◽  
Methanol Extract ◽  
Methanolic Extract ◽  
Entrapment Efficiency ◽  
Model Systems ◽  
Gas Chromatography Mass Spectrometry ◽  
Total Phenolic ◽  
Antioxidant Power ◽  
Reducing Ability

This study describes the synthesis of Protorhus longifolia methanolic leaf extract-loaded Eudragit nanoparticles (NPs) and assessment of their antioxidant activity comparative to the free methanolic extract. The latter was also analyzed for its total phenolic content (TPC) and total flavonoid content (TFC). The extract-loaded NPs were obtained through the emulsification solvent evaporation process and systematically characterized using the dynamic light scattering, entrapment efficiency, Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction (XRD) techniques. The antioxidant power was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing ability of plasma (FRAP) in vitro model systems. Screening of the different classes of secondary metabolites was carried out through chemical reaction tests. Identification of the potential antioxidants was performed using the gas chromatography-mass spectrometry (GC-MS) technique and the database of National Institute Standard and Technology (NIST). The characterization techniques showed spherical-like particles having an average size of 150[Formula: see text]nm and zeta potential of [Formula: see text]22[Formula: see text]mV. The percentage of entrapped methanolic extract was determined to be 83%. The antioxidant assay demonstrated that this methodology persuaded an efficient concentration-dependent potential. This study indicates that nanoformulation of the Protorhus longifolia extracts leads to a suitable system for the enhancement of antioxidant activity. The appraisal of other pharmacological activities of the nano-encapsulated Protorhus longifolia methanol extract is under process.

scholarly journals Synthesis, characterization of thiosemicarabzone metal complexes and antioxidant activity in different in vitro model systems

2013 ◽  
Vol 78 (2) ◽  
pp. 229-240 ◽  
Author(s):  
Kumar Reddy Harikishore ◽  
Seung-Mok Lee ◽  
Kalluru Seshaiah ◽  
Ramesh Babu
Keyword(s):  
Antioxidant Activity ◽  
Metal Complexes ◽  
In Vitro Model ◽  
Model Systems ◽  
Vitro Model

In Vitro Antioxidant and In Vivo Anti-Inflammatory Activities of Ophioglossum thermale

2012 ◽  
Vol 40 (02) ◽  
pp. 279-293 ◽  
Author(s):  
Xue-Qiong Zhang ◽  
Jin-Hwa Kim ◽  
Geun-Soo Lee ◽  
Hyeong-Bae Pyo ◽  
Eun-Young Shin ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Model Systems ◽  
Total Phenolic ◽  
Etoac Fraction ◽  
Anti Inflammatory

Antioxidant fractions from Ophioglossum thermale were extracted with five different polar solvents using a Soxhlet type extractor. The total phenolic content of the extracts was determined by the Folin-Ciocalteu method. The ethyl acetate fraction of O. thermale was found to contain maximum phenolics. The dried fractions were screened for their antioxidant activity potential using in vitro model systems such as 1,1-diphenyl-2-picryl hydrazyl (DPPH), nitroblue tetrazolium (NBT) and lipid-peroxidation reduction at different concentrations. Results revealed that the EtOAc fraction exhibited the best performance in the DPPH assay, NBT assay and lipid peroxidation. All fractions showed more potent antioxidant capacity than green tea extract, a well-known antioxidant. Furthermore, the EtOAc fraction has the highest total phenolic content (475.65 mg of EGCG/g). In addition, the EtOAc fraction at 0.005% and 0.01% (g/100 ml) also significantly inhibited UVB irradiation-induced ROS generation in human dermal fibroblasts (HDFs). In a carrageenan-induced edema model, the EtOAc fraction showed an inhibitory effect (21.5%, p < 0.05) at 200 mg/kg (p.o.) after 300 min administration. Consequently, 3-O-methylquercetin (3MQ) was also isolated from the antioxidative EtOAc fraction. The data obtained using the above in vitro and in vivo tests suggest that the antioxidant activity of O. thermale and its anti-inflammatory effect on carrageenan-induced acute inflammation can be attributed to its ameliorating effect on oxidative damage, and thus it has great potential as a source for natural health products. To the best of our knowledge, this is the first report on the antioxidant activity of different polar extracts from O. thermale.

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