Fatty acids of Thespesia populnea: Mass spectrometry of picolinyl esters of cyclopropene fatty acids

2011 ◽  
Vol 113 (8) ◽  
pp. 980-984 ◽  
Author(s):  
Gerhard Knothe ◽  
Umer Rashid ◽  
Suzana Yusup ◽  
Farooq Anwar
Keyword(s):  
Mass Spectrometry ◽  
Fatty Acids ◽  
Thespesia Populnea ◽  
Picolinyl Esters ◽  
Cyclopropene Fatty Acids

Proteomic analysis of cytochromes P450: a mass spectrometry approach

2006 ◽  
Vol 34 (6) ◽  
pp. 1246-1251 ◽  
Author(s):  
Y. Wang ◽  
A. Al-Gazzar ◽  
C. Seibert ◽  
A. Sharif ◽  
C. Lane ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Fatty Acids ◽  
Inborn Errors Of Metabolism ◽  
Cytochromes P450 ◽  
Acid Biosynthesis ◽  
Inborn Errors ◽  
Steroid Synthesis ◽  
Current State ◽  
Increased Risk ◽  
Risk Of Cancer

In human, the CYP (cytochrome P450) superfamily comprises 57 genes arranged in 18 families and 42 subfamiles. These genes encode for enzymes involved in the metabolism of drugs, foreign chemicals, fatty acids, eicosanoids and cholesterol. Additionally, they play roles in bile acid biosynthesis, steroid synthesis and metabolism, and vitamin D3 synthesis and metabolism. Mutations in many CYP genes cause inborn errors of metabolism and contribute to increased risk of cancer. MS provides a convenient method for the identification and quantification of CYP enzymes, and in the present paper we will review the current state of the technology for such an analysis.

Sign in / Sign up

Export Citation Format

Share Document