Bioinspired Oxidative Cleavage of Aliphatic C-C Bonds Utilizing Aerial Oxygen by Nickel Acireductone Dioxygenase Mimics

2019 ◽  
Vol 2019 (16) ◽  
pp. 2163-2163
Author(s):  
Sakthi Raje ◽  
Kalaikodikumaran Mani ◽  
Parameswaran Kandasamy ◽  
Ray J. Butcher ◽  
Raja Angamuthu
Keyword(s):  
Oxidative Cleavage ◽  
Acireductone Dioxygenase

scholarly journals Front Cover: Bioinspired Oxidative Cleavage of Aliphatic C-C Bonds Utilizing Aerial Oxygen by Nickel Acireductone Dioxygenase Mimics (Eur. J. Inorg. Chem. 16/2019)

2019 ◽  
Vol 2019 (16) ◽  
pp. 2162-2162
Author(s):  
Sakthi Raje ◽  
Kalaikodikumaran Mani ◽  
Parameswaran Kandasamy ◽  
Ray J. Butcher ◽  
Raja Angamuthu
Keyword(s):  
Oxidative Cleavage ◽  
Front Cover ◽  
Acireductone Dioxygenase

Bioinspired Oxidative Cleavage of Aliphatic C-C Bonds Utilizing Aerial Oxygen by Nickel Acireductone Dioxygenase Mimics

2019 ◽  
Vol 2019 (16) ◽  
pp. 2164-2167
Author(s):  
Sakthi Raje ◽  
Kalaikodikumaran Mani ◽  
Parameswaran Kandasamy ◽  
Ray J. Butcher ◽  
Raja Angamuthu
Keyword(s):  
Oxidative Cleavage ◽  
Acireductone Dioxygenase

Synthesis of (15E)-17β-hydroxy-5α-androstane-3,15-dione 15-[O-(Carboxymethyl)]oxime, New Hapten for Dihydrotestosterone (17β-hydroxy-5α-androstan-3-one)

1997 ◽  
Vol 62 (10) ◽  
pp. 1642-1649 ◽  
Author(s):  
Ivan Černý ◽  
Tereza Slavíková ◽  
Vladimír Pouzar
Keyword(s):  
Hydroxy Group ◽  
Carboxy Group ◽  
Title Compound ◽  
Oxidative Cleavage ◽  
Hydroxy Derivative ◽  
Borohydride Reduction ◽  
Protecting Group ◽  
Free Hydroxy Group

Addition of 4-methoxybenzyl alcohol to 3β-hydroxy-5α-androst-15-en-17-one gave the mixture of isomeric 15-(4-methoxyphenyl)methoxy derivatives from which, after acetylation and chromatography, the major 15β isomer was separated. Borohydride reduction gave 17β-hydroxy derivative which was protected as methoxymethyl ether. Oxidative cleavage of protecting group at position 15 and the subsequent Jones oxidation afforded corresponding 15-ketone. Its oximation with O-(carboxymethyl)hydroxylamine, deacetylation and methylation with diazomethane gave protected O-(carboxymethyl)oxime derivative with free hydroxy group at position 3. Its oxidation afforded dihydrotestosterone derivative and successive deprotection of position 17 and of carboxy group led to final (15E)-17β-hydroxy-5α-androstane-3,15-dione 15-[O-(carboxymethyl)]oxime. The title compound was designed as dihydrotestosterone hapten for heterologous radioimmunoassays.

Visible-light-initiated Catalyst-free Oxidative Cleavage of Triaryl-Substituted Alkenes C=C Bonds under Ambient Conditions

2021 ◽  
Author(s):  
Wenjing Li ◽  
Shun Li ◽  
Lihua Luo ◽  
Yichen Ge ◽  
Jiaqi Xu ◽  
...  
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Ambient Air ◽  
Oxidative Cleavage ◽  
Ambient Conditions ◽  
Blue Led ◽  
Catalyst Free

The catalyst-free oxidative cleavage of (Z)-triaryl-substituted alkenes bearing pyridyl motif with ambient air under irradiation of blue LED at room temperature has been developed. The reaction was facile and scalable,...

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