Comparative analysis of CreER transgenic mice for the study of brain macrophages: A case study

AbstractConditional mutagenesis and fate mapping have contributed considerably to our understanding of physiology and pathology. Specifically, Cre recombinase-based approaches allow the definition of cell type-specific contributions to disease development and inter-cellular communication circuits in respective animals models. Here we compared Cx3cr1CreER and Sall1CreER transgenic mice and their use to decipher the brain macrophage compartment as a showcase to discuss recent technological advances. Specifically, we highlight the need to define the accuracy of Cre recombinase expression, as well as strengths and pitfalls of these particular systems that should be taken into consideration when applying these models.

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COMPARATIVE ANALYSIS OF MOTIVATION OF CIVIL SERVANTS AND PUBLIC SERVANTS IN THE LOCAL STATE ADMINISTRATION – CASE STUDY OF SLOVAKIA

Central European Journal of Labour Law and Personnel Management ◽

10.33382/cejllpm.2019.02.06 ◽

2019 ◽

Cited By ~ 1

Keyword(s):

Comparative Analysis ◽

Local State ◽

Civil Servants ◽

Public Servants ◽

State Administration

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Improving the integrated reporting of electric-power industry companies

International Accounting ◽

10.24891/ia.23.8.922 ◽

2020 ◽

Vol 23 (8) ◽

pp. 922-939

Author(s):

N.V. Malinovskaya ◽

M.D. Malinovskii

Keyword(s):

Comparative Analysis ◽

Electric Power ◽

Electric Power Industry ◽

Power Industry ◽

Integrated Reporting ◽

Strategic Objectives ◽

Methods Of Analysis ◽

Analysis And Synthesis ◽

Guiding Principles

Subject. This article deals with the issues relating to improving integrated reporting in terms of dovetailing strategic objectives with capital changes. Objectives. The article aims to develop a system of indicators for disclosure of capital types in integrated reporting of electricity generating companies, as well as recommendations aimed at implementing the fundamental concepts and guiding principles of integrated reporting. Methods. For the study, we used the methods of analysis and synthesis, comparison, generalization, and abstraction. As a case study, we conduct a comparative analysis of the disclosure of six types of capital by the largest electricity generating companies, namely PAO Inter RAO, AO Rosenergoatom and PAO RusHydro. Results. The article formulates proposals for disclosure of capital information to address such a lack of accountability as a contradiction to the principle of coherence. It proposes a system of indicators (core and additional) for disclosure of six types of capital by electricity generating companies. Conclusions. A significant reporting problem is the lack of correlation between key strategic objectives and capital changes. The formulated recommendations for disclosure of capital information can help solve this problem, and increase the attractiveness of the integrated report for capital providers.

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