scholarly journals The IL‐12‐STAT4 axis in the pathogenesis of human systemic lupus erythematosus

2019 ◽  
Vol 50 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Hideki Ueno
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Human Systemic Lupus Erythematosus ◽  
Systemic Lupus

Organized Intraglomerular Deposits in NZB Mouse Disease

1971 ◽  
Vol 29 ◽  
pp. 544-545
Author(s):  
Francis R. Comerford ◽  
Alan S. Cohen
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Antinuclear Antibodies ◽  
Human Systemic Lupus Erythematosus ◽  
Systemic Lupus ◽  
Glomerular Lesion ◽  
Ultrastructural Studies ◽  
Dense Deposits ◽  
Experimental Nephritis ◽  
Glomerular Lesions

Mice of the inbred NZB strain develop a spontaneous disease characterized by autoimmune hemolytic anemia, positive lupus erythematosus cell tests and antinuclear antibodies and nephritis. This disease is analogous to human systemic lupus erythematosus. In ultrastructural studies of the glomerular lesion in NZB mice, intraglomerular dense deposits in mesangial, subepithelial and subendothelial locations were described. In common with the findings in many examples of human and experimental nephritis, including many cases of human lupus nephritis, these deposits were amorphous or slightly granular in appearance with no definable substructure.We have recently observed structured deposits in the glomeruli of NZB mice. They were uncommon and were found in older animals with severe glomerular lesions by morphologic criteria. They were seen most commonly as extracellular elements in subendothelial and mesangial regions. The deposits ranged up to 3 microns in greatest dimension and were often adjacent to deposits of lipid-like round particles of 30 to 250 millimicrons in diameter and with amorphous dense deposits.

scholarly journals FAS mRNA editing in human systemic lupus erythematosus

2011 ◽  
Vol 32 (11) ◽  
pp. 1268-1277 ◽  
Author(s):  
Jianming Wu ◽  
Fenglong Xie ◽  
Kun Qian ◽  
Andrew W. Gibson ◽  
Jeffrey C. Edberg ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Human Systemic Lupus Erythematosus ◽  
Mrna Editing ◽  
Systemic Lupus ◽  
Fas Mrna

scholarly journals Confirmation of genetic linkage between human systemic lupus erythematosus and chromosome 1q41

1999 ◽  
Vol 42 (9) ◽  
pp. 1902-1907 ◽  
Author(s):  
Kathy L. Moser ◽  
Courtney Gray-McGuire ◽  
Jennifer Kelly ◽  
Neeraj Asundi ◽  
Hua Yu ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Genetic Linkage ◽  
Human Systemic Lupus Erythematosus ◽  
Systemic Lupus ◽  
Chromosome 1Q41

Analysis of molecular heterogeneity of prolactin in human systemic lupus erythematosus

Lupus ◽  
2004 ◽  
Vol 13 (8) ◽  
pp. 575-583 ◽  
Author(s):  
M García ◽  
M E Colombani-Vidal ◽  
C C Zylbersztein ◽  
A Testi ◽  
J Marcos ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Molecular Heterogeneity ◽  
Human Systemic Lupus Erythematosus ◽  
Systemic Lupus

Expression and Function of Fas Antigen and bcl-2 in Human Systemic Lupus Erythematosus Lymphocytes

1994 ◽  
Vol 73 (1) ◽  
pp. 109-114 ◽  
Author(s):  
Satomi Ohsako ◽  
Masako Hara ◽  
Masayoshi Harigai ◽  
Chikako Fukasawa ◽  
Sadao Kashiwazaki
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Human Systemic Lupus Erythematosus ◽  
Systemic Lupus ◽  
Fas Antigen ◽  
And Function

scholarly journals Genome Screening in Human Systemic Lupus Erythematosus: Results from a Second Minnesota Cohort and Combined Analyses of 187 Sib-Pair Families

2000 ◽  
Vol 66 (2) ◽  
pp. 547-556 ◽  
Author(s):  
Patrick M. Gaffney ◽  
Ward A. Ortmann ◽  
Scott A. Selby ◽  
Katherine B. Shark ◽  
Theresa C. Ockenden ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Human Systemic Lupus Erythematosus ◽  
Systemic Lupus ◽  
Genome Screening
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