Expansion of follicular helper T cells in the absence of Treg cells: Implications for loss of B-cell anergy

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Key Points CD10 identifies a unique subset of fully functional germinal center TFH that are activated and amplified within the FL cell niche. FL CD10pos TFH specifically display an IL-4hiIFN-γlo cytokine profile and encompass the malignant B-cell-supportive TFH subset.


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H. Zhong ◽  
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Nadege Pelletier ◽  
Linda Mark ◽  
Nicolas Fazilleau ◽  
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Vol 26 (3) ◽  
pp. 183-192 ◽  
Author(s):  
Simone H. C. Havenith ◽  
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