scholarly journals Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling

2010 ◽  
Vol 41 (2) ◽  
pp. 491-502 ◽  
Author(s):  
Meidan Goldfinger ◽  
Miri Shmuel ◽  
Sandrine Benhamron ◽  
Boaz Tirosh
Keyword(s):  
Endoplasmic Reticulum ◽  
Protein Synthesis ◽  
Endoplasmic Reticulum Stress ◽  
Plasma Cells ◽  
Mtor Signaling

scholarly journals Fluoride Induces Endoplasmic Reticulum Stress and Inhibits Protein Synthesis and Secretion

2008 ◽  
Vol 116 (9) ◽  
pp. 1142-1146 ◽  
Author(s):  
Ramaswamy Sharma ◽  
Masahiro Tsuchiya ◽  
John D. Bartlett
Keyword(s):  
Endoplasmic Reticulum ◽  
Protein Synthesis ◽  
Endoplasmic Reticulum Stress

scholarly journals Algae Undaria pinnatifida Protects Hypothalamic Neurons against Endoplasmic Reticulum Stress through Akt/mTOR Signaling

Molecules ◽  
2015 ◽  
Vol 20 (12) ◽  
pp. 20998-21009 ◽  
Author(s):  
Jongwan Kim ◽  
Il Moon ◽  
Tae-Won Goo ◽  
Seong-Su Moon ◽  
Minchul Seo
Keyword(s):  
Endoplasmic Reticulum ◽  
Endoplasmic Reticulum Stress ◽  
Undaria Pinnatifida ◽  
Mtor Signaling ◽  
Hypothalamic Neurons

One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress

Blood ◽  
2014 ◽  
Vol 123 (22) ◽  
pp. 3440-3451 ◽  
Author(s):  
Ping Zhou ◽  
Xun Ma ◽  
Lakshmanan Iyer ◽  
Chakra Chaulagain ◽  
Raymond L. Comenzo
Keyword(s):  
Endoplasmic Reticulum ◽  
Endoplasmic Reticulum Stress ◽  
Light Chain ◽  
Antibody Production ◽  
Plasma Cells ◽  
Light Chains ◽  
Constant Region ◽  
Immunoglobulin Light Chain ◽  
Heavy Chains ◽  
Key Points

Key PointsImmunoglobulin light-chain and antibody production by plasma cells is significantly reduced by siRNA for the light-chain constant region. In plasma cells making intact antibodies, knockdown of light chains can cause terminal ER stress because of unpaired heavy chains.

scholarly journals Autophagy inhibition by biotin elicits endoplasmic reticulum stress to differentially regulate adipocyte lipid and protein synthesis

2019 ◽  
Vol 24 (2) ◽  
pp. 343-350 ◽  
Author(s):  
Senthilraja Selvam ◽  
Anand Ramaian Santhaseela ◽  
Dhasarathan Ganesan ◽  
Sudarshana Rajasekaran ◽  
Tamilselvan Jayavelu
Keyword(s):  
Endoplasmic Reticulum ◽  
Protein Synthesis ◽  
Endoplasmic Reticulum Stress ◽  
Autophagy Inhibition
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