scholarly journals Epstein-Barr virus (EBV)-positive lymphoproliferations in post-transplant patients show immunoglobulin V gene mutation patterns suggesting interference of EBV with normal B cell differentiation processes

2003 ◽  
Vol 33 (6) ◽  
pp. 1593-1602 ◽  
Author(s):  
Andreas Bräuninger ◽  
Tilmann Spieker ◽  
Anja Mottok ◽  
Audrey Sylvia Baur ◽  
Ralf Küppers ◽  
...  
Cell ◽  
1982 ◽  
Vol 30 (2) ◽  
pp. 415-425 ◽  
Author(s):  
David A. Thorley-Lawson ◽  
Robert T. Schooley ◽  
Atul K. Bhan ◽  
Lee M. Nadler

2006 ◽  
Vol 209 (3) ◽  
pp. 360-368 ◽  
Author(s):  
F Larousserie ◽  
E Bardel ◽  
A Coulomb L'Herminé ◽  
D Canioni ◽  
N Brousse ◽  
...  

Cureus ◽  
2021 ◽  
Author(s):  
Charlotte Lee ◽  
Helena Vincentelli ◽  
Jenni Visuri ◽  
Simon Knight ◽  
Rutger Ploeg

1996 ◽  
Vol 11 (6) ◽  
pp. 1164-1167 ◽  
Author(s):  
D. Hestin ◽  
M. Claudon ◽  
J. Champigneulles ◽  
E. Renoult ◽  
J. Hubert ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Lindsay C. Spender ◽  
Gareth J. Inman

To establish a persistent latent infection, Epstein-Barr virus (EBV) faces a challenge in that the virus-infected host cell must transit through the germinal centre reaction. This is a site of B cell differentiation where antibody responses are optimised, and the selection criteria for B cells are stringent. The germinal centre environment is harsh, and the vast majority of B cells here die by apoptosis. Only cells receiving adequate survival signals will differentiate fully to be released into the periphery as long-term memory B cells (the site of persistence). In this review, we detail the apoptotic pathways potentially encountered by EBV-infected B cells during the process of infection, and we describe the functions of those EBV-regulated cellular and viral genes that help promote survival of the host B cell.


2016 ◽  
Vol 48 (2) ◽  
pp. 110-118 ◽  
Author(s):  
María Dolores Fellner ◽  
Karina A. Durand ◽  
Veronica Solernou ◽  
Andrea Bosaleh ◽  
Ziomara Balbarrey ◽  
...  

1996 ◽  
Vol 11 (6) ◽  
pp. 1164-1167
Author(s):  
D. Hestin ◽  
M. Claudon ◽  
J. Champigneulles ◽  
E. Renoult ◽  
J. Hubert ◽  
...  

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