Regulation of delayed-type hypersensitivity I. T suppressor cells for delayed-type hypersensitivity to sheep erythrocytes in mice

1977 ◽  
Vol 7 (10) ◽  
pp. 714-718 ◽  
Author(s):  
F.Y. Liew
Keyword(s):  
Suppressor Cells ◽  
Delayed Type Hypersensitivity ◽  
Sheep Erythrocytes ◽  
T Suppressor Cells

Effects of confinement (110 and 240 days) on neuroendocrine stress response and changes of immune cells in men

2002 ◽  
Vol 92 (4) ◽  
pp. 1619-1627 ◽  
Author(s):  
A. Choukèr ◽  
L. Smith ◽  
F. Christ ◽  
I. Larina ◽  
I. Nichiporuk ◽  
...  
Keyword(s):  
Stress Test ◽  
Suppressor Cells ◽  
Delayed Type Hypersensitivity ◽  
Immunological Parameters ◽  
Enhanced Expression ◽  
Hypersensitivity Skin ◽  
Male Subjects ◽  
A Current ◽  
T Suppressor Cells

The aim of the study was to evaluate the effects of long-term confinement on stress-permissive neuroendocrine and immune responses in humans. Two groups of four male subjects were confined 240 days ( group 240) or 110 days ( group 110) in two space modules of 100 or 200 m3, respectively. During confinement, none of the volunteers developed psychic stress as could be examined and verified by a current stress test. However, in g roup 240 but not in group 110, the diurnal rhythm of cortisol secretion was slightly depressed and the urine excretion of norepinephrine significantly increased. The innate part of the immune system became activated as seen by a rise in the number of circulating granulocytes and the enhanced expression of β2-integrins. In contrast, the ratio of T-helper to T-suppressor cells decreased. All these effects, observed during confinement, were even more pronounced in both groups when values of endocrinological and immunological parameters were compared between before and 1 wk after the end of the confinement period. Hence, return to normal life exerts pronounced effects to a much higher degree, irrespective of how long or under which conditions individuals were confined. Because the delayed-type hypersensitivity skin reaction against recall antigens remained unaffected, it is to be presumed that confinement appears to induce distinct sympathoadrenergic activation and immunological changes but no clinically relevant immunosuppression.

Manipulation of autoimmune diseases with T-suppressor cells: lessons from experimental SLE and EAE

1993 ◽  
Vol 36 (2) ◽  
pp. 109-116 ◽  
Author(s):  
Yehuda Shoenfeld ◽  
Miri Blank ◽  
Rina Aharoni ◽  
Dvora Teitelbaum ◽  
Ruth Arnon
Keyword(s):  
Autoimmune Diseases ◽  
Suppressor Cells ◽  
T Suppressor Cells

scholarly journals Identification of lymphocyte subpopulations with a polymethine dye.

1988 ◽  
Vol 36 (7) ◽  
pp. 711-715 ◽  
Author(s):  
L Kass
Keyword(s):  
Suppressor Cells ◽  
Buffy Coat ◽  
Lymphocyte Subpopulations ◽  
Rapid Screening ◽  
T Helper ◽  
Yellow Orange ◽  
A Cell ◽  
Health And Disease ◽  
T Suppressor Cells ◽  
Polymethine Dye

Using the polymethine dye p-ethoxyphenyl-p-aminostyryl-1,3,3-trimethyl-3H-indolium chloride as an aqueous stain applied to specimens of peripheral blood or buffy coat fixed in FAA fixative, differential coloration of leukocytes was achieved using darkfield illumination. Neutrophils stained dark maroon and contained green granules, eosinophils contained bright blue granules, basophils revealed yellow and pink granules, and monocytes stained green with green and yellow vacuoles. In studies of purified lymphocyte subpopulations obtained in a cell sorter, T-helper cells stained red, T-suppressor cells were yellow orange, B-cells appeared yellow and often contained yellow annular structures in the cytoplasm, and natural killer (NK) cells stained green and contained large green granules. As a rapid screening technique for identification of T-helper and T-suppressor cells and their ratios in health and disease, the new polymethine stain may complement the more complex monoclonal antibody techniques for identification of these cells.

Inhibition of graft-versus-host reactions by t suppressor cells and non-t suppressor cells

1986 ◽  
Vol 10 (1) ◽  
pp. 124
Author(s):  
A. Molendijk ◽  
A. van Oudenaren ◽  
H. Bril ◽  
R. Benner
Keyword(s):  
Suppressor Cells ◽  
Graft Versus Host ◽  
T Suppressor Cells

Regulation of contact sensitivity reaction: Contrasuppressor T cells and contrasuppressor factor downregulate efferent T suppressor cells

1992 ◽  
Vol 144 (1) ◽  
pp. 95-104 ◽  
Author(s):  
Włodzimierz Ptak ◽  
Krzysztof Bryniarski ◽  
Marian Szczepanik ◽  
Maria Ptak ◽  
Agnieszka Polewska
Keyword(s):  
T Cells ◽  
Suppressor Cells ◽  
Contact Sensitivity ◽  
Sensitivity Reaction ◽  
T Suppressor Cells
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