scholarly journals Growth differentiation factor 15 in heart failure with preserved vs. reduced ejection fraction

2015 ◽  
Vol 18 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Michelle M.Y. Chan ◽  
Rajalakshmi Santhanakrishnan ◽  
Jenny P.C. Chong ◽  
Zhaojin Chen ◽  
Bee Choo Tai ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Growth Differentiation Factor 15 ◽  
Reduced Ejection Fraction ◽  
Differentiation Factor

scholarly journals Growth differentiation factor 15 as mortality predictor in heart failure patients with non‐reduced ejection fraction

2020 ◽  
Vol 7 (5) ◽  
pp. 2223-2229
Author(s):  
Ana Belen Mendez Fernandez ◽  
Andreu Ferrero‐Gregori ◽  
Alvaro Garcia‐Osuna ◽  
Sonia Mirabet‐Perez ◽  
Maria Jose Pirla‐Buxo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Growth Differentiation Factor 15 ◽  
Reduced Ejection Fraction ◽  
Heart Failure Patients ◽  
Differentiation Factor

scholarly journals Growth-differentiation factor-15 improves reclassification for the diagnosis of heart failure with normal ejection fraction in morbid obesity

2012 ◽  
Vol 14 (11) ◽  
pp. 1240-1248 ◽  
Author(s):  
Andrea Baessler ◽  
Christina Strack ◽  
Elena Rousseva ◽  
Florian Wagner ◽  
Janine Bruxmeier ◽  
...  
Keyword(s):  
Heart Failure ◽  
Morbid Obesity ◽  
Ejection Fraction ◽  
Normal Ejection Fraction ◽  
Growth Differentiation Factor 15 ◽  
Differentiation Factor

scholarly journals The novel biomarker growth differentiation factor 15 in heart failure with normal ejection fraction

2010 ◽  
Vol 12 (12) ◽  
pp. 1309-1316 ◽  
Author(s):  
Raoul Stahrenberg ◽  
Frank Edelmann ◽  
Meinhard Mende ◽  
Anke Kockskämper ◽  
Hans-Dirk Düngen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Normal Ejection Fraction ◽  
The Novel ◽  
Growth Differentiation Factor 15 ◽  
Differentiation Factor

Heart Failure with Preserved Ejection Fraction – A Review

2012 ◽  
Vol 9 (1) ◽  
pp. 90-95 ◽  
Author(s):  
Otto A Smiseth ◽  
Anders Opdahl ◽  
Espen Boe ◽  
Helge Skulstad
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Diastolic Heart Failure ◽  
The Elderly ◽  
Left Ventricular ◽  
Filling Pressure ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Reduced Ejection Fraction ◽  
Objective Evidence

Heart failure with preserved left ventricular ejection fraction (HF-PEF), sometimes named diastolic heart failure, is a common condition most frequently seen in the elderly and is associated with arterial hypertension and left ventricular (LV) hypertrophy. Symptoms are attributed to a stiff left ventricle with compensatory elevation of filling pressure and reduced ability to increase stroke volume by the Frank-Starling mechanism. LV interaction with stiff arteries aggravates these problems. Prognosis is almost as severe as for heart failure with reduced ejection fraction (HF-REF), in part reflecting co-morbidities. Before the diagnosis of HF-PEF is made, non-cardiac etiologies must be excluded. Due to the non-specific nature of heart failure symptoms, it is essential to search for objective evidence of diastolic dysfunction which, in the absence of invasive data, is done by echocardiography and demonstration of signs of elevated LV filling pressure, impaired LV relaxation, or increased LV diastolic stiffness. Antihypertensive treatment can effectively prevent HF-PEF. Treatment of HF-PEF is symptomatic, with similar drugs as in HF-REF.

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