scholarly journals Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high‐risk combination. A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology

2020 ◽  
Vol 22 (8) ◽  
pp. 1298-1314 ◽  
Author(s):  
Veli‐Pekka Harjola ◽  
John Parissis ◽  
Johann Bauersachs ◽  
Hans‐Peter Brunner‐La Rocca ◽  
Hector Bueno ◽  
...  
Keyword(s):  
Heart Failure ◽  
High Risk ◽  
Acute Heart Failure ◽  
European Society ◽  
Acute Coronary Syndromes ◽  
Diagnostic Dilemma ◽  
Coronary Syndromes ◽  
European Society Of Cardiology

scholarly journals Long-term safety of intravenous cardiovascular agents in acute heart failure: results from the European Society of Cardiology Heart Failure Long-Term Registry

2017 ◽  
Vol 20 (2) ◽  
pp. 332-341 ◽  
Author(s):  
Alexandre Mebazaa ◽  
Justina Motiejunaite ◽  
Etienne Gayat ◽  
Maria G. Crespo-Leiro ◽  
Lars H. Lund ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
European Society ◽  
Cardiovascular Agents ◽  
European Society Of Cardiology

Abstract 5584: Heart Failure Eliminates the Risk Gradient Defined by TIMI Risk Score in Non-st-segment Elevation Acute Coronary Syndromes

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Sara S Gonçalves ◽  
Pedro Amador ◽  
Lígia Mendes ◽  
Filipe Seixo ◽  
José F Santos
Keyword(s):  
Heart Failure ◽  
High Risk ◽  
Hospital Mortality ◽  
Risk Score ◽  
Acute Coronary Syndromes ◽  
Clinical Registry ◽  
St Segment Elevation ◽  
St Segment ◽  
Coronary Syndromes ◽  
Timi Risk Score

The TIMI Risk Score is a simple and effective tool for risk stratification in patients (pts) with non-ST-segment elevation acute coronary syndromes (NSTE-ACS). The presence of heart failure (HF) or a low ejection fraction (EF) has also been associated with a worse outcome. We sought to evaluate the interaction of heart failure on the risk gradient defined by the TIMI Risk Score in a NSTE-ACS population. We studied 9980 pts with NSTE-ACS included in a prospective nationwide clinical registry since 2002. Pts were stratified by TIMI Risk Score in low (0 to 2), intermediate (3 and 4) and high risk (5 to 7) groups. The population was divided in two groups according to the presence or absence of HF. HF was defined as the presence of a Killip class >1 or a systolic EF <30%. In-hospital mortality or re-infarction was assessed in both groups during the index hospitalization and according to TIMI Risk Score Stratification. Results: In-hospital mortality or re-infarction was 1,9% in low risk, 3,7% in intermediate and 6,3% in high risk pts (Qui-square trend p<0,001). The risk gradient defined by the TIMI risk score was not observed in patients without HF (Qui-Square for trend=ns). In pts with HF, the TIMI risk score maintains its predictor value (Qui-square trend=0,014), but the presence of HF identifies a higher risk subgroup. In this population, HF was a strong independent predictor for in-hospital mortality and re-infarction (OR 10,01). In NSTE-ACS pts, the presence of HF identifies the patients with higher risk for in-hospital risk and re-infarction within each TIMI Risk Score subgroup. There was no risk gradient assessed by the TIMI risk score in the absence of HF.

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