scholarly journals Systolic time intervals in patients with heart failure: time to teach new dogs old tricks

2020 ◽  
Vol 22 (7) ◽  
pp. 1183-1185
Author(s):  
Joyce N. Njoroge ◽  
John R. Teerlink
Keyword(s):  
Heart Failure ◽  
Failure Time ◽  
Systolic Time Intervals ◽  
Time Intervals ◽  
Patients With Heart Failure ◽  
Systolic Time

scholarly journals Systolic Time Intervals in Heart Failure in Man

Circulation ◽  
1968 ◽  
Vol 37 (2) ◽  
pp. 149-159 ◽  
Author(s):  
ARNOLD M. WEISSLER ◽  
WILLARD S. HARRIS ◽  
CLYDE D. SCHOENFELD
Keyword(s):  
Heart Failure ◽  
Systolic Time Intervals ◽  
Time Intervals ◽  
Systolic Time

Comparison of Action of β-Methyldigoxin and Digoxin Utilizing Systolic Time Intervals

1980 ◽  
Vol 8 (1) ◽  
pp. 50-55
Author(s):  
A D Katdare ◽  
S A Namjoshi ◽  
K G Nair
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Ejection Fraction ◽  
Oral Administration ◽  
Systolic Time Intervals ◽  
Rapid Onset ◽  
Time Interval ◽  
Time Intervals ◽  
Temporal Course ◽  
Systolic Time

The temporal course of orally and parenterally administered β-methyl-digoxin and orally administered digoxin was studied in a series of twenty patients who suffered from congestive heart failure due to a variety of causes. The parameters studied mainly were systolic time intervals. The incontrovertible conclusion was that β-methyldigoxin acts almost immediately when administered intravenously and after 20 minutes when given by mouth. The peak action, however, by either route of administration was evident at the end of 45 minutes. Viewed in comparison, digoxin after oral administration acted after 2 hours, reaching its peak action after 8 hours. It must be admitted, however, that the magnitude of the response to both drugs, as measured by significant reduction in PEP/L VET ratio and increase in ejection fraction, was the same. Our study suggests that β-methyldigoxin is as effective an inotropic agent as digoxin, with an additional characteristic of total and rapid gastrointestinal absorption, predictable and rapid onset and much shorter time interval for its peak action.

scholarly journals Usefulness of systolic time intervals in the identification of abnormal ventriculo-arterial coupling in stable heart failure patients*

2008 ◽  
Vol 10 (12) ◽  
pp. 1192-1200 ◽  
Author(s):  
Hao-Min Cheng ◽  
Wen-Chung Yu ◽  
Shih-Hsien Sung ◽  
Kang-Ling Wang ◽  
Shao-Yuan Chuang ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systolic Time Intervals ◽  
Time Intervals ◽  
Heart Failure Patients ◽  
Systolic Time
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