scholarly journals Left atrial strain and compliance in the diagnostic evaluation of heart failure with preserved ejection fraction

2019 ◽  
Vol 21 (7) ◽  
pp. 891-900 ◽  
Author(s):  
Yogesh N.V. Reddy ◽  
Masaru Obokata ◽  
Alexander Egbe ◽  
Jeong Hoon Yang ◽  
Sorin Pislaru ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Diagnostic Evaluation ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

scholarly journals Impaired left atrial strain predicts abnormal exercise haemodynamics in heart failure with preserved ejection fraction

2019 ◽  
Vol 21 (4) ◽  
pp. 495-505 ◽  
Author(s):  
Fernando Telles ◽  
Shane Nanayakkara ◽  
Shona Evans ◽  
Hitesh C. Patel ◽  
Justin A. Mariani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

Left atrial strain in heart failure with preserved ejection fraction

Herz ◽  
2016 ◽  
Vol 42 (2) ◽  
pp. 194-199 ◽  
Author(s):  
S. M. Aung ◽  
A. Güler ◽  
Y. Güler ◽  
A. Huraibat ◽  
C. Y. Karabay ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

P1481B-lines and left atrial strain in outpatients with suspected heart failure with preserved ejection fraction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
G Agoston ◽  
L Gargani ◽  
I Szabo ◽  
B Illes ◽  
A Varga
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Lung Ultrasound ◽  
Preserved Ejection Fraction ◽  
Pulmonary Congestion ◽  
Left Atrial Strain ◽  
Atrial Strain ◽  
Left Atrial Dysfunction ◽  
B Lines

Abstract Background Heart Failure with Preserved Ejection Fraction (HFpEF) is a growing healthcare burden and its prevalence is increasing. Diagnosing HFpEF is challenging. Lung ultrasound (LUS) and left atrial strain are promising tools to assess pulmonary congestion and left atrial dysfunction in outpatient settings in patients with suspected HFpEF. Aim To evaluate the correlation of LUS B-lines with left atrial strain in patients with HFpEF. Methods Thirty-six consecutive patients (24 women, mean age 70±6 years) with clinical signs of heart failure were prospectively enrolled. Exclusion criteria were: ejection fraction <55%, more than mild mitral and/or aortic valve disease, pulmonary disease, pulmonary arterial hypertension. Within one hour all patients underwent comprehensive echocardiographic evaluation including left atrial strain analysis (peak atrial longitudinal strain-PALS), lung ultrasound assessment of B-lines on the antero-lateral and posterior chest wall, and NT-proBNP levels. Results The mean ejection fraction was 65.5±8.6%. In 28 patients (85%) a significant number of B-lines (≥15) was observed. We found a positive correlation between the number of B-lines and NT-proBNP levels (p<0.0001, r: 0.76, Figure 1.), left atrial volume (p<0.05, r: 0.45), and PALS (p<0.05, r: −0.5, Figure 2.). We didn't found any correlation between the number of B-lines and E/e'ratio (p=0.1, r: 0.28), or between E/e' ratio and NT-proBNP level (p=0.2, r: 0.2). Conclusion LUS is a simple, feasible tool to detect pulmonary congestion in HFpEF and it seems to better characterize these patients. B-lines correlate well with NT-proBNP values and with parameters of left atrial dysfunction. PALS is a promising too which better reflects pulmonary congestion and elevated NT-proBNP values than the conventional echocardiographic parameter E/e'.

scholarly journals CARDIOVASCULAR OUTCOME OF LEFT ATRIAL STRAIN IN HEART FAILURE WITH PRESERVED EJECTION FRACTION

2021 ◽  
Vol 77 (18) ◽  
pp. 1337
Author(s):  
Norifumi Bekki ◽  
Hiromasa Hayama ◽  
Ran Nagai ◽  
Wataru Miyake ◽  
Jumpei Yamamoto ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Cardiovascular Outcome ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

scholarly journals Diagnosis of heart failure with preserved ejection fraction in patients with dyspnea and paroxysmal atrial fibrillation: a role of left atrial strain

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Katbeh ◽  
T De Potter ◽  
P Geelen ◽  
G Di Gioia ◽  
M Kodeboina ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Speckle Tracking ◽  
High Probability ◽  
Funding Source ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

Abstract Background Diagnosis of heart failure with preserved ejection fraction (HFpEF) in patients with dyspnea and paroxysmal atrial fibrillation (AF) is challenging. Speckle tracking-derived left atrial strain (LAS) provides an accurate estimate of left ventricular filling pressures and left atrial phasic function. However, data on clinical utility of LAS in patients with dyspnea and AF are scarce. Objective To assess relationship between LAS and probability of HFpEF in patients with dyspnea and paroxysmal AF. Methods The study included 205 consecutive patients (62±10 years, 58% males) with limiting dyspnea (NYHA ≥ II), paroxysmal AF and preserved LVEF (≥50%), who underwent speckle tracking echocardiography and natriuretic peptide (NT-proBNP) assessment during sinus rhythm. Patients with manifest ischemic heart or valve disease, and cardiomyopathy were excluded. Probability of HFpEF was estimated using H2FPEF and HFA-PEFF scores, which combine clinical characteristics, echocardiographic parameters and natriuretic peptides. Results A total of 61 (30%), 115 (56%) and 29 (14%) had respectively high, intermediate and low probability of HFpEF. Patients with high probability of HFpEF were significantly older, had higher body mass index, NT-proBNP, E/e', pulmonary artery pressure and larger LA volume index than patients in low-to-intermediate probability groups (all p&lt;0.05). Two distinct patterns of LA phasic function were observed. Firstly, reservoir LAS showed close inverse association with increasing probability of HFpEF. Secondly, contractile LAS showed initial decrease with subsequent compensatory increase in intermediate probability category with final decrease in patients with high HFpEF probability. In contrast, LV global longitudinal strain was similar between groups (NS). In multivariable regression analysis, reservoir LAS emerged as the strongest independent predictor of HFpEF defined by using both scores. Reservoir LAS with optimal cut off value of 24% showed sensitivity of 86% and specificity of 70% to identify high probability of HFpEF. Combination of LAS with NT-proBNP did not increase the accuracy of each parameter alone. Conclusions Reservoir LAS shows a strong independent association with probability of HFpEF in patients with dyspnea and paroxysmal AF. This advocates for more liberal use of LAS assessment to distinguish cardiac from non-cardiac dyspnea in patients with history of AF. Funding Acknowledgement Type of funding source: Public Institution(s). Main funding source(s): International PhD programme in Cardiovascular Pathophysiology and Therapeutics (CardioPaTh).

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