scholarly journals Pulmonary artery wedge pressure respiratory variation is correlated with haemodynamic improvement with increased left ventricular assist system speed

2018 ◽  
Vol 21 (2) ◽  
pp. 251-253 ◽  
Author(s):  
Devin Blankinship ◽  
Marc R. Katz ◽  
Lucian Lozonschi ◽  
Ryan J. Tedford ◽  
Brian A. Houston
Keyword(s):  
Pulmonary Artery ◽  
Left Ventricular ◽  
Respiratory Variation ◽  
Pulmonary Artery Wedge Pressure ◽  
Left Ventricular Assist System ◽  
Ventricular Assist ◽  
Left Ventricular Assist ◽  
Wedge Pressure ◽  
Haemodynamic Improvement

Abstract 19236: Effect of Continuous Flow Left Ventricular Assist Device on Diastolic Pulmonary Artery Pressure-to-Pulmonary Capillary Wedge Pressure Gradient in End Stage Heart Failure Patients with Pulmonary Hypertension

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Thenappan Thenappan ◽  
Rebecca Cogswell ◽  
Forum Kamdar ◽  
Christopher Holley ◽  
Laura Harvey ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Vascular Remodeling ◽  
Continuous Flow ◽  
Left Ventricular ◽  
Ventricular Assist ◽  
Pulmonary Vascular Remodeling ◽  
Pulmonary Capillary ◽  
Left Ventricular Assist ◽  
End Stage ◽  
Wedge Pressure

Background: Continuous flow left ventricular assist devices (LVAD) reduces transpulmonary gradient (TPG) and pulmonary vascular resistance (PVR) in end-stage HF patients with pulmonary venous hypertension (PVH). However, TPG and PVR are flow dependent and may not reflect intrinsic pulmonary vascular remodeling. Diastolic pulmonary artery pressure-to-pulmonary capillary wedge pressure gradient (DPG) has been shown to more accurately reflect pulmonary vascular remodeling. Objective: We sought to evaluate the effect of LVAD on DPG in end-stage HF patients with PVH (mPAP > 25 mm Hg and PCWP > 15 mm Hg). Methods: We retrospectively reviewed clinical and hemodynamic data on 116 end-stage HF patients with PVH who underwent LVAD implantation and analyzed changes in DPG between pre- and first post-LVAD right heart catheterization (RHC). Results: The mean age was 55 ± 14 years and 78% were males. Of the 116 patients, 83 patients had pre-LVAD DPG 7 mm Hg (Combined post-and pre-capillary PVH). The median duration between the pre-and post-LVAD RHC was 147 (IQR: 106-302) days. Table below compares pre-and post-LVAD hemodynamics. In patients with combined post-and pre-capillary PVH, LVAD therapy significantly decreased DPG (9 ± 4 vs. 6 ± 6; P<0.001). However, 42% of these patients did not lower DPG to <7 mmHg with LVAD therapy (non-responders). On multivariate regression, higher pre-LVAD DPG was the only independent factor associated with non-responders. Pre-LVAD DPG >8 mm Hg had 77% sensitivity and 88% specificity for identifying non-responders (AUC 0.82). Conclusion: Although DPG decreased after LVAD therapy, it remained significantly elevated (>7mm Hg) in a subset of patients with combined post-and pre-capillary PVH. DPG >8 mm Hg is significantly associated with non-response to LVAD therapy. Additional studies are warranted to assess the impact of these findings on outcomes.

Initial clinical experience with the heartware left ventricular assist system

2012 ◽  
Vol 60 (S 01) ◽  
Author(s):  
AM Dell'Aquila ◽  
S Schneider ◽  
D Schlarb ◽  
J Sindermann ◽  
A Hoffmeier ◽  
...  
Keyword(s):  
Clinical Experience ◽  
Left Ventricular ◽  
Left Ventricular Assist System ◽  
Ventricular Assist ◽  
Left Ventricular Assist ◽  
Initial Clinical Experience

Pulmonary Artery Wedge Pressure Respiratory Variation Increases With Sodium Nitroprusside Vasodilator Challenge

2020 ◽  
Vol 26 (12) ◽  
pp. 1096-1099
Author(s):  
Steven P. Maurides ◽  
Devin Blankinship ◽  
Kavin Panneerselvam ◽  
Gregory R. Jackson ◽  
Stefano Ghio ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Sodium Nitroprusside ◽  
Respiratory Variation ◽  
Pulmonary Artery Wedge Pressure ◽  
Wedge Pressure

Results of the Registry To EValuate the HeartWare Left Ventricular Assist System (The REVOLVE Registry)

2013 ◽  
Vol 32 (4) ◽  
pp. S11 ◽  
Author(s):  
M. Strueber ◽  
R. Larbalestier ◽  
P. Jansz ◽  
D. Zimpfer ◽  
A.E. Fiane ◽  
...  
Keyword(s):  
Left Ventricular ◽  
Left Ventricular Assist System ◽  
Ventricular Assist ◽  
Left Ventricular Assist

RETROSPECTIVE ANALYSIS OF INFECTION IN A GROUP OF LEFT VENTRICULAR ASSIST SYSTEM (LVAS) PATIENTS

ASAIO Journal ◽  
1996 ◽  
Vol 42 (2) ◽  
pp. 44
Author(s):  
W. Springer ◽  
A. Wasler ◽  
B. Radovancevic ◽  
T. Myers ◽  
M. P. Macris ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Left Ventricular ◽  
Left Ventricular Assist System ◽  
Ventricular Assist ◽  
Left Ventricular Assist

Results of the European Clinical Trial of Arrow CorAide Left Ventricular Assist System

2012 ◽  
Vol 37 (2) ◽  
pp. 121-127 ◽  
Author(s):  
Diyar Saeed ◽  
Latif Arusoglu ◽  
Fabrizio Gazzoli ◽  
Roland Hetzer ◽  
Michael Morshius ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Left Ventricular ◽  
Left Ventricular Assist System ◽  
Ventricular Assist ◽  
Left Ventricular Assist
Sign in / Sign up

Export Citation Format

Share Document