scholarly journals Interaction of systolic blood pressure and resting heart rate with clinical outcomes in takotsubo syndrome: insights from the International Takotsubo Registry

2018 ◽  
Vol 20 (6) ◽  
pp. 1021-1030 ◽  
Author(s):  
Michael Böhm ◽  
Victoria L. Cammann ◽  
Jelena R. Ghadri ◽  
Christian Ukena ◽  
Sebastiano Gili ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Clinical Outcomes ◽  
Takotsubo Syndrome ◽  
Resting Heart Rate

Abstract P021: Association Of Resting Heart Rate With All-cause And Cardiovascular Mortality: Sprint

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Steven J Mould ◽  
Elsayed Z Soliman ◽  
Yashashwi Pokharel ◽  
Elijah Beaty ◽  
Prashant Bhave ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Cardiovascular Mortality ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Channel Blockers ◽  
Resting Heart Rate ◽  
Autonomic Tone

Introduction: Elevated resting heart rate (RHR) has been shown to be associated with both all-cause and cardiovascular mortality. Prior studies have provided conflicting estimates of the strength of each association. To explore the relationship between RHR and competing mortality risks, we sought to compare the association between RHR and cardiovascular and non-cardiovascular mortality among participants in the Systolic Blood Pressure Intervention Trial (SPRINT). Methods: Eligible SPRINT participants had baseline RHR, longitudinal follow-up, and were not using beta blockers or non-dihydropyridine calcium channel blockers. Mortality was classified by a treatment-blinded adjudication committee as cardiovascular if secondary to coronary heart disease, stroke, sudden cardiac death, or congestive heart failure. Multivariable Cox proportional hazards models were used to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CI) for cardiovascular and non-cardiovascular mortality, separately, associated with a 10 beats per minute increase in RHR. Results: Among 5,571 eligible SPRINT participants (67.1 ± 9.4 years, 33.8% female, 63.8% white, mean RHR 70.4±11.8 beats per minute) over a median 3.8 years of follow-up, there were 56 cardiovascular deaths and 176 non-cardiovascular deaths. In models adjusted for age, sex, race, prior cardiovascular disease, smoking, systolic blood pressure, creatinine, total cholesterol, high-density lipoprotein cholesterol, and trial treatment assignment, higher RHR (per ten beat-per-minute increase) was associated with both cardiovascular (HR 1.17, 95% CI 1.02-1.35) and non-cardiovascular mortality (HR 1.27, 95% CI 1.13-1.43). Conclusions: Elevated RHR was associated with both cardiovascular and non-cardiovascular mortality, suggesting that RHR may serve as a marker of both global health rather and cardiovascular health. Higher RHR may reflect imbalance in autonomic tone and further studies are needed to explore the mechanisms of these associations.4

The Effects of an Incremental Approach to 10,000 Steps/Day on Metabolic Syndrome Components in Sedentary Overweight Women

2010 ◽  
Vol 7 (6) ◽  
pp. 737-745 ◽  
Author(s):  
Anthony Musto ◽  
Kevin Jacobs ◽  
Mark Nash ◽  
Gianluca DelRossi ◽  
Arlette Perry
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Heart Rate ◽  
Waist Circumference ◽  
Systolic Blood Pressure ◽  
Fasting Glucose ◽  
Resting Heart Rate ◽  
Overweight Women ◽  
Metabolic Syndrome Components

Background:Pedometer programs can increase physical activity in sedentary individuals, a population that is at risk for developing metabolic syndrome and each of its individual components. Although the popular 10,000 steps/day recommendation has shown to induce many favorable health benefits, it may be out of reach for sedentary individuals. This study observed the effects of incremental increases in steps/day on metabolic syndrome components in sedentary overweight women.Methods:This study was a longitudinal, quasiexperimental design. Participants were recruited from a 12-week work-site pedometer program and grouped as either ‘active’ or ‘control’ after the intervention based on their steps/day improvement. Self-reported physical activity, pedometer assessed physical activity, BMI, resting heart rate, waist circumference, blood pressure, triglycerides, HDLC, and fasting glucose were measured before and after the program.Results:The active group showed significant within-group improvements in waist circumference and fasting glucose. Significant group differences were observed in resting heart rate, BMI, and systolic blood pressure; however, the changes observed in systolic blood pressure were not independent of weight loss.Conclusions:Incremental increases in steps/day induced favorable changes in some MetS components suggesting that this approach is a viable starting point for sedentary individuals that may find it difficult to initially accumulate 10,000 steps/day.

Association between Physical Activity and Blood Pressure in Normotensive Adults

1993 ◽  
Vol 76 (2) ◽  
pp. 701-702
Author(s):  
John E. Martin ◽  
Christi A. Patten ◽  
Colin A. Armstrong
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Habitual Physical Activity ◽  
Resting Heart Rate

In 18 normotensive adults (15 women, 3 men), higher levels of habitual physical activity were significantly associated with lower diastolic blood pressure, but not with systolic blood pressure or resting heart rate.

scholarly journals Cardiovascular and metabolic risk markers are related to parasympathetic indices in pre-pubertal adolescents

2015 ◽  
Vol 26 (2) ◽  
pp. 280-287 ◽  
Author(s):  
Suziane U. Cayres ◽  
Luiz Carlos M. Vanderlei ◽  
Danilo R. P. Silva ◽  
Manoel Carlos S. Lima ◽  
Maurício F. Barbosa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Blood Flow ◽  
Heart Rate Variability ◽  
Linear Regression ◽  
Systolic Blood Pressure ◽  
Linear Regression Analysis ◽  
Parasympathetic Activity ◽  
Resting Heart Rate ◽  
Increased Risk

AbstractObjectiveTo analyse the relationship between different heart rate variability indices, resting heart rate, and cardiovascular markers in adolescents.MethodsA cross-sectional study was carried out with information from an ongoing cohort study. The sample was composed of 99 adolescents who complied with the following inclusion criteria: aged between 11 and 14 years; enrolled in a school unit of elementary education; absence of any known diseases; no drug consumption; and a formal consent signed by the parents or legal guardians. Weight, height, heart rate variability, lipid profile, inflammatory markers, blood pressure, resting heart rate, intima-media thickness, blood flow, and trunk fatness were measured. Partial correlation and linear regression (expressed by β and 95% confidence intervals [95%CI]) analyses were used to analyse the relationships between the variables.ResultsIn the linear regression analysis, even after adjustments for sex, age, trunk fatness, and somatic maturation, parasympathetic activity presented significant correlations with maximum carotid artery blood flow (β=−0.111 [95%CI=−0.216; −0.007]), systolic blood pressure (β=−0.319 [95%CI=−0.638; −0.001]), and resting heat rate (β=−0.005 [95%CI=−0.009; −0.002]).ConclusionParasympathetic activity at rest is inversely related to maximum and minimum blood flow, triacylglycerol levels, and systolic blood pressure. These findings suggest that heart rate variability has the potential to discriminate pre-pubertal adolescents at increased risk.

scholarly journals Resting Heart Rate and Cardiovascular Outcomes during Intensive and Standard Blood Pressure Reduction: An Analysis from SPRINT Trial

2021 ◽  
Vol 10 (15) ◽  
pp. 3264
Author(s):  
Piotr Sobieraj ◽  
Maciej Siński ◽  
Jacek Lewandowski
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Risk Factor ◽  
Systolic Blood Pressure ◽  
Blood Pressure Reduction ◽  
Cardiovascular Death ◽  
Hazard Ratio ◽  
Resting Heart Rate ◽  
Coronary Syndrome ◽  
The Relationship

The association between elevated resting heart rate (RHR) as a cardiovascular risk factor and lowering of systolic blood pressure (SBP) to currently recommended values remain unknown. Systolic Blood Pressure Intervention Trial (SPRINT) data obtained from the NHLBI were used to describe the relationship between RHR and SBP reduction to <120 mmHg compared to SBP reduction to <140 mmHg. The composite clinical endpoint (CE) was defined as myocardial infarction, acute coronary syndrome, decompensation of heart failure, stroke, or cardiovascular death. Increased RHR was associated with a higher CE risk compared with low RHR in both treatment arms. A more potent increase of risk for CE was observed in subjects who were allocated to the SBP < 120 mmHg treatment goal. A similar effect of intensive and standard blood pressure (BP) reduction (p for interaction, 0.826) was observed in subjects with RHR in the 5th quintile (hazard ratio, 0.78, with 95% confidence interval (CI), 0.55–1.11) and in other quintiles of baseline RHR (hazard ratio, 0.75, with 95% CI, 0.62–0.90). Lower in-trial than baseline RHR was associated with reduced CE risk (hazard ratio, 0.80, with 95% CI, 0.66–0.98). We concluded that elevated RHR remains an essential risk factor independent of SBP reduction.

scholarly journals Systolic blood pressure at admission and long‐term clinical outcomes in patients hospitalized for heart failure

2021 ◽  
Author(s):  
Xinghe Huang ◽  
Jiamin Liu ◽  
Shuang Hu ◽  
Lihua Zhang ◽  
Fengyu Miao ◽  
...  
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Clinical Outcomes
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