scholarly journals Heart failure is associated with an increased incidence of cancer diagnoses

2021 ◽  
Author(s):  
Christoph Roderburg ◽  
Sven H. Loosen ◽  
Julia K. Jahn ◽  
Julia Gänsbacher ◽  
Tom Luedde ◽  
...  
Keyword(s):  
Heart Failure ◽  
Incidence Of Cancer

Does the pathophysiology of heart failure prime the incidence of cancer?

2017 ◽  
Vol 40 (9) ◽  
pp. 831-836 ◽  
Author(s):  
Mari Sakamoto ◽  
Takuya Hasegawa ◽  
Masanori Asakura ◽  
Hideaki Kanzaki ◽  
Hiroyuki Takahama ◽  
...  
Keyword(s):  
Heart Failure ◽  
Incidence Of Cancer

scholarly journals INCREASED INCIDENCE OF CANCER AMONG HEART FAILURE PATIENTS: A LONG-TERM FOLLOW-UP STUDY

2014 ◽  
Vol 63 (12) ◽  
pp. A952
Author(s):  
Ann Bøcher Secher Banke ◽  
Morten Schou ◽  
Lars Videbaek ◽  
Christian Torp-Pedersen ◽  
Finn Gustafsson ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Failure Patients ◽  
Follow Up Study ◽  
Incidence Of Cancer ◽  
Long Term Follow Up

scholarly journals INCIDENCE OF CANCER INCREASED IN PATIENTS WITH CHRONIC HEART FAILURE

2015 ◽  
Vol 65 (10) ◽  
pp. A828
Author(s):  
Mari Sakamoto ◽  
Masanori Asakura ◽  
Akira Funada ◽  
Makoto Amaki ◽  
Takahiro Ohara ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Incidence Of Cancer

scholarly journals Prior History and Incidence of Cancer Impacts on Cardiac Prognosis in Hospitalized Patients With Heart Failure

2019 ◽  
Vol 83 (8) ◽  
pp. 1709-1717 ◽  
Author(s):  
Akiomi Yoshihisa ◽  
Yasuhiro Ichijo ◽  
Koichiro Watanabe ◽  
Yu Sato ◽  
Yuki Kanno ◽  
...  
Keyword(s):  
Heart Failure ◽  
Hospitalized Patients ◽  
Prior History ◽  
Incidence Of Cancer ◽  
Patients With Heart Failure

scholarly journals Incidence of cancer in patients with chronic heart failure: a long-term follow-up study

2016 ◽  
Vol 18 (3) ◽  
pp. 260-266 ◽  
Author(s):  
Ann Banke ◽  
Morten Schou ◽  
Lars Videbaek ◽  
Jacob E. Møller ◽  
Christian Torp-Pedersen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Follow Up Study ◽  
Incidence Of Cancer ◽  
Long Term Follow Up

Mitochondria in Cardiomyopathy: Alterations in Size, Number and Internal Structures

1968 ◽  
Vol 26 ◽  
pp. 126-127
Author(s):  
George Hug ◽  
William K. Schubert
Keyword(s):  
Heart Failure ◽  
Biochemical Analysis ◽  
Left Ventricular ◽  
Size Number ◽  
Internal Structures ◽  
Left Ventricular Outflow ◽  
Chest X Ray ◽  
Myocardial Fibers ◽  
Muscle Biopsies ◽  
Needle Liver Biopsy

A white boy six months of age was hospitalized with respiratory distress and congestive heart failure. Control of the heart failure was achieved but marked cardiomegaly, moderate hepatomegaly, and minimal muscular weakness persisted.At birth a chest x-ray had been taken because of rapid breathing and jaundice and showed the heart to be of normal size. Clinical studies included: EKG which showed biventricular hypertrophy, needle liver biopsy which showed toxic hepatitis, and cardiac catheterization which showed no obstruction to left ventricular outflow. Liver and muscle biopsies revealed no biochemical or histological evidence of type II glycogexiosis (Pompe's disease). At thoracotomy, 14 milligrams of left ventricular muscle were removed. Total phosphorylase activity in the biopsy specimen was normal by biochemical analysis as was the degree of phosphorylase activation. By light microscopy, vacuoles and fine granules were seen in practically all myocardial fibers. The fibers were not hypertrophic. The endocardium was not thickened excluding endocardial fibroelastosis. Based on these findings, the diagnosis of idiopathic non-obstructive cardiomyopathy was made.

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

Protective role of peroxiredoxin-4 in heart failure

2020 ◽  
Vol 134 (1) ◽  
pp. 71-72
Author(s):  
Naseer Ahmed ◽  
Masooma Naseem ◽  
Javeria Farooq
Keyword(s):  
Heart Failure ◽  
Cardiac Fibroblasts ◽  
Protective Role ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Galectin 3 ◽  
Consequent Increase ◽  
And Oxidative Stress

Abstract Recently, we have read with great interest the article published by Ibarrola et al. (Clin. Sci. (Lond.) (2018) 132, 1471–1485), which used proteomics and immunodetection methods to show that Galectin-3 (Gal-3) down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers in cardiac fibroblasts.’ We would like to point out some results stated in the article that need further investigation and more detailed discussion to clarify certain factors involved in the protective role of Prx-4 in heart failure.

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