scholarly journals Non‐invasive telemonitoring improves outcomes in heart failure with reduced ejection fraction: a study in high‐risk patients

2020 ◽  
Vol 7 (6) ◽  
pp. 3996-4004
Author(s):  
Afonso Nunes‐Ferreira ◽  
João R. Agostinho ◽  
Joana Rigueira ◽  
Inês Aguiar‐Ricardo ◽  
Tatiana Guimarães ◽  
...  
Keyword(s):  
Heart Failure ◽  
High Risk ◽  
Ejection Fraction ◽  
Reduced Ejection Fraction ◽  
High Risk Patients ◽  
Non Invasive ◽  
Risk Patients

scholarly journals P1831Hemodynamics and its predictors during impella-protected pci in high risk patients with reduced ejection fraction

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
G Russo ◽  
F Burzotta ◽  
D D'Amario ◽  
F Ribichini ◽  
A Piccoli ◽  
...  
Keyword(s):  
High Risk ◽  
Ejection Fraction ◽  
Reduced Ejection Fraction ◽  
High Risk Patients ◽  
Risk Patients

scholarly journals TCT-452 Hemodynamics and its Predictors During Impella-Protected PCI in High Risk Patients with Reduced Ejection Fraction

2018 ◽  
Vol 72 (13) ◽  
pp. B182
Author(s):  
Giulio Russo ◽  
Francesco Burzotta ◽  
Domenico D'Amario ◽  
Flavio Ribichini ◽  
Anna Piccoli ◽  
...  
Keyword(s):  
High Risk ◽  
Ejection Fraction ◽  
Reduced Ejection Fraction ◽  
High Risk Patients ◽  
Risk Patients

Hemodynamics and its predictors during Impella-protected PCI in high risk patients with reduced ejection fraction

2019 ◽  
Vol 274 ◽  
pp. 221-225 ◽  
Author(s):  
Giulio Russo ◽  
Francesco Burzotta ◽  
Domenico D'Amario ◽  
Flavio Ribichini ◽  
Anna Piccoli ◽  
...  
Keyword(s):  
High Risk ◽  
Ejection Fraction ◽  
Reduced Ejection Fraction ◽  
High Risk Patients ◽  
Risk Patients

Prognostic role of myocardial work in patients with heart failure and reduced ejection fraction treated by sacubitril/valsartan

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
E Galli ◽  
Y Bouali ◽  
C Laurin ◽  
A Gallard ◽  
A Hubert ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Rank Test ◽  
Reduced Ejection Fraction ◽  
Non Invasive ◽  
Patients With Heart Failure ◽  
Increase Risk ◽  
Echocardiographic Examination ◽  
Constructive Work

Abstract Background The non-invasive assessment of myocardial work (MW) by pressure-strain loops analysis (PSL) is a relative new tool for the evaluation of myocardial performance. Sacubitril/Valsartan is a treatment for heart failure with reduced ejection fraction (HFrEF) which has a spectacular effect on the reduction of cardiovascular events (MACEs). Purposes of this study were to evaluate 1) the short and medium term effect of Sacubitril/Valsartan treatment on MW parameters; 2) the prognostic value of MW in this specific group of patients. Methods 79 patients with HFrEF (mean age: 66±12 years; LV ejection fraction: 28±9%) were prospectively included in the study and treated with Sacubitril/Valsartan. Echocardiographic examination was performed at baseline, and after 6- and 12-month of therapy with Sacubitril/Valsartan. Results Sacubitril/Valsartan significantly increased global myocardial constructive work (CW) (1023±449 vs 1424±484 mmHg%, p<0.0001) and myocardial work efficiency (WE) [87 (78–90) vs 90 (86–95), p<0.0001]. During FU (2.6±0.9 years), MACEs occurred in 13 (16%) patients. After correction for LV size, LVEF and WE, CW was the only predictor of MACEs (Table 1). A CW<910 mmHg (AUC=0.81, p<0.0001, Figure 1A) identified patients at particularly increase risk of MACEs [HR 11.09 (1.45–98.94), p=0.002, log-rank test p<0.0001] (Figure 1 B). Conclusions In patients with HFrEF who receive a comprehensive background beta-blocker and mineral-corticoid receptor antagonist therapy, Sacubitril/Valsartan induces a significant improvement of myocardial CW and WE. In this population, the estimation of CW before the initiation of Sacubitril/Valsartan therapy allows the prediction of MACEs. Funding Acknowledgement Type of funding source: None

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