scholarly journals Prognostic impact of nutritional status and physical capacity in elderly patients with acute decompensated heart failure

2020 ◽  
Vol 7 (4) ◽  
pp. 1801-1808 ◽  
Author(s):  
Kaori Yasumura ◽  
Haruhiko Abe ◽  
Yoshinori Iida ◽  
Taishi Kato ◽  
Masayuki Nakamura ◽  
...  
Keyword(s):  
Heart Failure ◽  
Nutritional Status ◽  
Elderly Patients ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Physical Capacity ◽  
Prognostic Impact

Prognostic Impact and Underlying Mechanism of Hypoalbuminemia in Elderly Patients With Acute Decompensated Heart Failure

2009 ◽  
Vol 15 (7) ◽  
pp. S150
Author(s):  
Yoshiharu Kinugasa ◽  
Masahiko Kato ◽  
Shinobu Sugihara ◽  
Masayuki Hirai ◽  
Katsunori Ishida ◽  
...  
Keyword(s):  
Heart Failure ◽  
Elderly Patients ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Underlying Mechanism ◽  
Prognostic Impact

scholarly journals Delirium is Associated with High Mortality in Elderly patients with Acute Decompensated Heart Failure

2020 ◽  
Author(s):  
Misun Pak ◽  
Masahiko Hara ◽  
Shoko Miura ◽  
Motohide Furuya ◽  
Masatake Tamaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Elderly Patients ◽  
High Mortality ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
The Elderly ◽  
Prognostic Impact ◽  
Clinical Frailty Scale ◽  
All Cause Mortality

Abstract Background: Delirium is associated with high mortality after cardiac surgery. However, evidence on the epidemiology of delirium in patients with acute decompensated heart failure (ADHF) is limited. This study aimed to assess the incidence and prognostic impact of delirium in patients with ADHF.Methods: This single-center prospective observational study enrolled 132 consecutive patients with ADHF. We utilized the Diagnostic and Statistical Manual of Mental Disorders, fifth edition and classified the patients into two groups according to the presence or absence of delirium. The primary endpoint was 90-day all-cause mortality. The prognostic impact and risk factors of delirium were evaluated using multivariable Cox and logistic regression analyses, respectively. Results: The median patient age was 83 (interquartile range, 75–87) years. Approximately 51.5% were men. Delirium occurred in 36 (27.3%) patients, and hyperactive delirium was the most frequent type (86.1%). The 90-day all-cause mortality was higher in the patients with delirium than in those without (21.6% versus 3.9%, log-rank p=0.002). Delirium was associated with higher mortality with an adjusted hazard ratio of 6.8 (95% confidence interval, 1.1–42.6, p=0.042). The risk factors associated with delirium included advanced age, male sex, higher clinical frailty scale score, and dementia.Conclusions: Delirium was associated with a higher 90-day all-cause mortality in the elderly patients with ADHF. Hyperactive delirium was the most common subtype.

scholarly journals Delirium is associated with high mortality in elderly patients with acute decompensated heart failure

2020 ◽  
Author(s):  
Misun Pak ◽  
Masahiko Hara ◽  
Shoko Miura ◽  
Motohide Furuya ◽  
Masatake Tamaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Elderly Patients ◽  
High Mortality ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
The Elderly ◽  
Prognostic Impact ◽  
Clinical Frailty Scale ◽  
All Cause Mortality

Abstract Background: Delirium is associated with high mortality after cardiac surgery. However, evidence on the epidemiology of delirium in patients with acute decompensated heart failure (ADHF) is limited. This study aimed to assess the incidence and prognostic impact of delirium in patients with ADHF. Methods: This single-center prospective observational study enrolled 132 consecutive patients with ADHF. We utilized the Diagnostic and Statistical Manual of Mental Disorders, fifth edition and classified the patients into two groups according to the presence or absence of delirium. The primary endpoint was 90-day all-cause mortality. The prognostic impact and risk factors of delirium were evaluated using multivariable Cox and logistic regression analyses, respectively. Results: The median patient age was 83 (interquartile range, 75–87) years. Approximately 51.5% were men. Delirium occurred in 36 (27.3%) patients, and hyperactive delirium was the most frequent type (86.1%). The 90-day all-cause mortality was higher in the patients with delirium than in those without (21.6% versus 3.9%, log-rank p=0.002). Delirium was associated with higher mortality with an adjusted hazard ratio of 6.8 (95% confidence interval, 1.1–42.6, p=0.042). The risk factors associated with delirium included advanced age, male sex, higher clinical frailty scale score, and dementia. Conclusions: Delirium was associated with a higher 90-day all-cause mortality in the elderly patients with ADHF. Hyperactive delirium was the most common subtype.

scholarly journals Delirium is associated with high mortality in elderly patients with acute decompensated heart failure

2020 ◽  
Author(s):  
Misun Pak ◽  
Masahiko Hara ◽  
Shoko Miura ◽  
Motohide Furuya ◽  
Masatake Tamaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Elderly Patients ◽  
High Mortality ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
The Elderly ◽  
Prognostic Impact ◽  
Clinical Frailty Scale ◽  
All Cause Mortality

Abstract Background: Delirium is associated with high mortality after cardiac surgery. However, evidence on the epidemiology of delirium in patients with acute decompensated heart failure (ADHF) is limited. This study aimed to assess the incidence and prognostic impact of delirium in patients with ADHF. Methods: This single-center prospective observational study enrolled 132 consecutive patients with ADHF. We utilized the Diagnostic and Statistical Manual of Mental Disorders, fifth edition and classified the patients into two groups according to the presence or absence of delirium. The primary endpoint was 90-day all-cause mortality. The prognostic impact and risk factors of delirium were evaluated using multivariable Cox and logistic regression analyses, respectively. Results: The median patient age was 83 (interquartile range, 75–87) years. Approximately 51.5% were men. Delirium occurred in 36 (27.3%) patients, and hyperactive delirium was the most frequent type (86.1%). The 90-day all-cause mortality was higher in the patients with delirium than in those without (21.6% versus 3.9%, log-rank p=0.002). Delirium was associated with higher mortality with an adjusted hazard ratio of 6.8 (95% confidence interval, 1.1–42.6, p=0.042). The risk factors associated with delirium included advanced age, male sex, higher clinical frailty scale score, and dementia. Conclusions: Delirium was associated with a higher 90-day all-cause mortality in the elderly patients with ADHF. Hyperactive delirium was the most common subtype.

scholarly journals NUTRITIONAL STATUS AND ITS IMPACT ON PROGNOSIS IN ELDERLY PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE

2014 ◽  
Vol 63 (12) ◽  
pp. A553
Author(s):  
Masahito Shigekiyo ◽  
Ayumi Okada ◽  
Kazunori Takeichi ◽  
Tatsuhiko Shiraishi ◽  
Akira Hirono ◽  
...  
Keyword(s):  
Heart Failure ◽  
Nutritional Status ◽  
Elderly Patients ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure

Abstract 14471: Prognostic Impact of Sarcopenia in Men versus Women With Acute Decompensated Heart Failure and Preserved Left Ventricular Ejection Fraction

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Takanari Kimura ◽  
Shungo Hikoso ◽  
Nakatani Daisaku ◽  
Shunsuke Tamaki ◽  
Masamichi Yano ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Left Ventricular ◽  
Fat Free Mass ◽  
Left Ventricular Ejection ◽  
Prognostic Impact ◽  
Ventricular Ejection Fraction ◽  
Multicenter Observational Study

Background: Sarcopenia is associated with poor prognosis in chronic heart failure. Fat-free mass index (FFMI) is an indicator of resting energy expenditure and has been used for the clinical diagnosis of sarcopenia. However, the prognostic impact of sarcopenia diagnosed by FFMI remains to be elucidated in patients admitted with acute decompensated heart failure (ADHF) and preserved LVEF (HFpEF), relating to gender. Methods: Patients' data were extracted from The Prospective mUlticenteR obServational stUdy of patIenTs with Heart Failure with Preserved Ejection Fraction (PURSUIT-HFpEF) study, which is a prospective multicenter observational registry for ADHF patients with LVEF ≥50% in Osaka. We studied 621 patients who survived to discharge (men, n=281 and women, n=340). Fat-free mass (FFM) was estimated by the formula [FFM (kg) = 7.38 + 0.02908 х urinary creatinine (mg/day)] and normalized by the square of the patient’s height in meters to calculate FFMI at discharge. Sarcopenia was defined as FFMI <17 kg/m2 in men and <15 kg/m2 in women. The endpoint was all-cause death. Results: During a follow-up period of 1.5±0.8 yrs, 102 patients died (men, n=46 and women, n=56). At multivariate Cox analysis, FFMI was significantly associated with the mortality independently of age, estimated glomerular filtration rate, NT-proBNP and LVEF in both men (p=0.0155) and women (p=0.0223). Patients with sarcopenia had a significantly higher risk of all-cause death than those without sarcopenia in both genders (Figure). Conclusions: In this multicenter study, sarcopenia diagnosed by FFMI was shown to be associated with poor clinical outcome in HFpEF patients admitted with ADHF in both genders.

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