scholarly journals The chameleon of cardiology: cardiac sarcoidosis before and after heart transplantation

2019 ◽  
Vol 7 (2) ◽  
pp. 692-696 ◽  
Author(s):  
Farbod Sedaghat‐Hamedani ◽  
Elham Kayvanpour ◽  
Sonja Hamed ◽  
Lutz Frankenstein ◽  
Johannes Riffel ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Cardiac Sarcoidosis ◽  
Before And After

Total 12-Lead QRS Voltage in Patients Having Orthotopic Heart Transplantation for Heart Failure Caused by Adriamycin-Induced Cardiomyopathy

Cardiology ◽  
2018 ◽  
Vol 141 (3) ◽  
pp. 172-175 ◽  
Author(s):  
William C. Roberts ◽  
Sarah Haque ◽  
Shelley A. Hall
Keyword(s):  
Heart Failure ◽  
Heart Transplantation ◽  
Cardiac Amyloidosis ◽  
Cardiac Sarcoidosis ◽  
Medical Center ◽  
Severe Heart Failure ◽  
Orthotopic Heart Transplantation ◽  
S Wave ◽  
Baylor University ◽  
Before And After

Objective: Although several studies have described the effects of adriamycin on the heart, electrocardiographic total 12-lead QRS voltage (distance in millimeters from the peak of the R wave to the nadir of either the Q or S wave, whichever was deeper, with 10 mm [1 mV] being standard) both before and after orthotopic heart transplantation (OHT) has not been reported. This study describes the total 12-lead QRS voltage in 8 patients studied at Baylor University Medical Center at Dallas, from 1994 to June 2018, who underwent OHT for severe heart failure caused by anthracycline-induced cardiomyopathy. Method: Prior to OHT, the total 12-lead non-paced QRS voltages ranged from 86 to 189 mm (mean 125 ± 56) and for paced QRS voltages from 82 to 113 mm (mean 97 ± 15). The total 12-lead QRS voltages post-OHT ranged from 100 to 190 mm (mean 130 ± 30). Total 12-lead QRS voltages were lower in patients with a pacemaker than without. Results/Conclusion: These low voltages are like those found in patients with carcinoid syndrome, severe cardiac adiposity, cardiac amyloidosis, and cardiac sarcoidosis.

Cardiac sarcoidosis in the donor heart without extracardiac manifestations

2021 ◽  
Vol 14 (4) ◽  
pp. e241902
Author(s):  
Mohammad Al-Ani ◽  
Mohamad Badie Taha ◽  
Brian D Stewart ◽  
Gabrielle S Graves ◽  
Mustafa M Ahmed ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Functional Imaging ◽  
Heart Block ◽  
Cardiac Sarcoidosis ◽  
Systolic Dysfunction ◽  
Donor Heart ◽  
Post Transplantation ◽  
Aged Woman ◽  
Middle Aged Woman ◽  
End Stage

A middle-aged woman who received heart transplantation for end-stage sarcoid cardiomyopathy developed recurrent cardiac sarcoidosis in the donor heart. She presented 5 years post-transplantation with heart block and systolic dysfunction, without extracardiac involvement. Her disease was unresponsive to corticosteroids. Routine functional imaging may help identify such recurrences.

The Corrected QT Interval Before and After Heart Transplantation

2009 ◽  
Vol 104 (4) ◽  
pp. 596-601 ◽  
Author(s):  
Jeremy P. Moore ◽  
Juan C. Alejos ◽  
Gregory Perens ◽  
Samantha Wong ◽  
Kevin M. Shannon
Keyword(s):  
Heart Transplantation ◽  
Qt Interval ◽  
Corrected Qt Interval ◽  
Before And After

Heart Transplantation for End-Stage Heart Failure Due to Cardiac Sarcoidosis

2013 ◽  
Vol 45 (6) ◽  
pp. 2384-2386 ◽  
Author(s):  
D. Perkel ◽  
L.S.C. Czer ◽  
R.P. Morrissey ◽  
A. Ruzza ◽  
M. Rafiei ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Transplantation ◽  
Cardiac Sarcoidosis ◽  
End Stage Heart Failure ◽  
End Stage

P5415Sleep disordered breathing in patients before and after heart transplantation: association with biomarkers and clinical parameters

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
E Medvedeva ◽  
L S Korostovtseva ◽  
M A Simonenko ◽  
Y V Sazonova ◽  
Y V Sviryaev
Keyword(s):  
Heart Failure ◽  
Sleep Apnea ◽  
Heart Transplantation ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Clinical Parameters ◽  
Ventricular Ejection Fraction ◽  
Obstructive Sleep ◽  
Before And After ◽  
Disordered Breathing

Abstract Background Sleep-disordered breathing (SDB) is highly frequent in patients with severe heart failure (HF). SDB, and predominantly central sleep apnea (CSA), may improve after recovery of cardiac function, but available data are limited and inconclusive, especially in patients who have undergone heart transplantation. The assessment of the severity of sleep apnea is mainly based on the apnea-hypopnea index (AHI), but this event-based parameter alone may not sufficiently reflect the complex pathophysiological mechanisms underlying SDB potentially contributing to adverse outcomes in patients with heart failure. Purpose To assess SDB in patients with severe HF before and after heart transplantation, their relationship with biomarkers and clinical parameters. Methods We included 117 patients (mean age 52.4±4.7 years) with HF NYHA class II-IV in the prospective cohort study, follow-up period was 5 years. The left ventricular ejection fraction (LVEF) was 28.05±9.57%. All patients underwent a comprehensive clinical examination, echocardiography, polysomnography (PSG, Embla N7000, Natus, USA). The plasma level of NT-proBNP, was analyzed by immunoassay (ELISA). The SPSS statistical software (version 23.0) was used. Results PSG showed the following types of SDB in the studied cohort: obstructive sleep apnoea (OSA) was diagnosed in 48 patients (41%), central - in 20 (17%), mixed - in 26 (22%). Among them mild SDB was diagnosed in 29 cases, moderate in 32 and severe in 33 patients. SDB was not found in 23 patients. The following correlations were identified: NT-proBNP and obstructive apnea index (OAI) (r=−0.44, p=0.007), NT-proBNP and sleep efficiency (r=−0.71, p=0.006), AHI and body mass index (BMI) (r=0.32, p=0.01), OAI and BMI index (r=0.34, p<0.001), desaturation index and BMI (r=0.43, p<0.001), average saturation oxygen and BMI (r=−0,6, p<0,001). Twenty-three patients underwent heart transplantation. According PSG-data 1 year after transplantation we observed decrease of central apnea index (CAI) (p=0,04). On the other hand, OAI increased (p=0,01) independently of the significant change in BMI (p=0,08). Conclusion We found very high rate of SDB (80%) in patients with severe HF, the predominant type was OSA. AHI, OAI and indicators of oxygen saturation correlate with BMI and biomarkers before heart transplantation. After 1 year after transplantation CAI decreased, assessment of the dynamics of obstructive sleep apnea requires further study.

NITRIC OXIDE EFFECT ON PULMONARY HYPERTENSION BEFORE AND AFTER HEART TRANSPLANTATION

1998 ◽  
Vol 86 (Supplement) ◽  
pp. 35SCA
Author(s):  
J Karski ◽  
R DeBrouwere ◽  
C Feindel ◽  
D Cheng
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Hypertension ◽  
Heart Transplantation ◽  
Before And After

THE TNF-α SYSTEM BEFORE AND AFTER HEART TRANSPLANTATION: PLASMA PROTEIN LEVELS, mRNA-EXPRESSION, SOLUBLE RECEPTORS AND SERUM BUFFER CAPACITY

1998 ◽  
Vol 65 (Supplement) ◽  
pp. 234
Author(s):  
I. C. van Riemsdijk ◽  
C. C. Baan ◽  
E. H.M. Loonen ◽  
C. J. Hesse ◽  
A. H.M.M. Balk ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Mrna Expression ◽  
Plasma Protein ◽  
Buffer Capacity ◽  
Soluble Receptors ◽  
Protein Levels ◽  
Tnf Α ◽  
Before And After
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