scholarly journals Effect of precipitating factors of acute heart failure on readmission and long‐term mortality

2016 ◽  
Vol 3 (2) ◽  
pp. 115-121 ◽  
Author(s):  
Mattia Arrigo ◽  
Heli Tolppanen ◽  
Malha Sadoune ◽  
Elodie Feliot ◽  
Antonio Teixeira ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Precipitating Factors ◽  
Long Term Mortality

scholarly journals Impact of diabetes mellitus on mortality in patients with acute heart failure: a prospective cohort study

2020 ◽  
Author(s):  
Min Gyu Kong ◽  
Se Yong Jang ◽  
Jieun Jang ◽  
Hyun-Jai Cho ◽  
Sangjun Lee ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Glycemic Control ◽  
Ejection Fraction ◽  
Acute Heart Failure ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Inadequate Glycemic Control ◽  
Long Term Mortality

Abstract Background Although more than one third of the patients with acute heart failure (AHF) have diabetes mellitus (DM), it is unclear whether DM exerts adverse impact on clinical outcomes. This study aimed to compare the outcomes in patients hospitalized for AHF in accordance with DM and left ventricular ejection fraction (LVEF). Methods The Korean Acute Heart Failure registry prospectively enrolled and completed follow-up of 5,625 patients from March 2011 to February 2019. Primary endpoints were in-hospital and overall all-cause mortality. We evaluated the impact of DM on these mortalities according to HF subtypes and glycemic control. Results DM was significantly associated with increased long-term mortality (adjusted hazard ratio [HR], 1.12; 95% confidence interval [CI], 1.02-1.22) even after adjusting for potential confounders. In subgroup analysis according to LVEF, DM was associated with higher long-term mortality in only HF with reduced ejection fraction (HFrEF) (adjusted HR, 1.14; 95% CI, 1.02-1.27). Inadequate glycemic control defined by HbA1c ≥ 7.0% within 1 year after discharge was significantly associated with higher long-term mortality compared to adequate glycemic control (HbA1c <7.0%) (44.0% vs. 36.8%; Log-rank p =0.016). Conclusions This large registry data showed that DM and inadequate glycemic control were significantly associated with increased long-term mortality in AHF, especially HFrEF. Tight glucose control is required to mitigate long-term mortality.

Hypoalbuminemia in Acute Heart Failure Patients: Causes and Its Impact on Hospital and Long-Term Mortality

2014 ◽  
Vol 20 (5) ◽  
pp. 350-358 ◽  
Author(s):  
Juan Luis Bonilla-Palomas ◽  
Antonio Luis Gámez-López ◽  
Mirian Moreno-Conde ◽  
María Cristina López-Ibáñez ◽  
Manuel Anguita-Sánchez ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Heart Failure Patients ◽  
Long Term Mortality

scholarly journals Evaluation of Thyroid Function in Patients Hospitalized for Acute Heart Failure

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Ana Rita Leite ◽  
João Sérgio Neves ◽  
Marta Borges-Canha ◽  
Catarina Vale ◽  
Madalena von Hafe ◽  
...  
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Clinical Outcomes ◽  
Acute Heart Failure ◽  
Thyroid Function ◽  
Short Term ◽  
Cardiovascular Parameters ◽  
Adjusted Model ◽  
Long Term Mortality

Background. Thyroid hormones (TH) are crucial for cardiovascular homeostasis. Recent evidence suggests that acute cardiovascular conditions, particularly acute heart failure (AHF), significantly impair the thyroid axis. Our aim was to evaluate the association of thyroid function with cardiovascular parameters and short- and long-term clinical outcomes in AHF patients. Methods. We performed a single-centre retrospective cohort study including patients hospitalized for AHF between January 2012 and December 2017. We used linear, logistic, and Cox proportional hazard regression models to analyse the association of thyroid-stimulating hormone (TSH) and free thyroxine (FT4) with inpatient cardiovascular parameters, in-hospital mortality, short-term adverse clinical outcomes, and long-term mortality. Two models were used: (1) unadjusted, and (2) adjusted for age and sex. Results. Of the 235 patients included, 59% were female, and the mean age was 77.5 (SD 10.4) years. In the adjusted model, diastolic blood pressure was positively associated with TSH [β = 2.68 (0.27 to 5.09); p = 0.030 ]; left ventricle ejection fraction (LVEF) was negatively associated with FT4 [β = -24.85 (-47.87 to -1.82); p = 0.035 ]; and a nonsignificant trend for a positive association was found between 30-day all-cause mortality and FT4 [OR = 3.40 (0.90 to 12.83); p = 0.071 ]. Among euthyroid participants, higher FT4 levels were significantly associated with a higher odds of 30-day all-cause death [OR = 4.40 (1.06 to 18.16); p = 0.041 ]. Neither TSH nor FT4 levels were relevant predictors of long-term mortality in the adjusted model. Conclusions. Thyroid function in AHF patients is associated with blood pressure and LVEF during hospitalization. FT4 might be useful as a biomarker of short-term adverse outcomes in these patients.

A simple parameter for long-term mortality in acute heart failure patients: serum albumin

2019 ◽  
pp. 1-1
Author(s):  
Tufan Çınar ◽  
Mert İlker Hayıroğlu ◽  
Vedat Çiçek ◽  
Ahmet Lütfullah Orhan
Keyword(s):  
Heart Failure ◽  
Serum Albumin ◽  
Acute Heart Failure ◽  
Heart Failure Patients ◽  
Simple Parameter ◽  
Long Term Mortality

scholarly journals Precipitating Factors for Acute Heart Failure Hospitalization and Long-Term Survival

Medicine ◽  
2015 ◽  
Vol 94 (52) ◽  
pp. e2330 ◽  
Author(s):  
Anat Berkovitch ◽  
Elad Maor ◽  
Avi Sabbag ◽  
Fernando Chernomordik ◽  
Avishay Elis ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Precipitating Factors ◽  
Heart Failure Hospitalization ◽  
Term Survival ◽  
Long Term Survival

scholarly journals GALECTIN-3, CARDIAC STRUCTURE AND FUNCTION, AND LONG-TERM MORTALITY IN PATIENTS WITH ACUTE HEART FAILURE

2010 ◽  
Vol 55 (10) ◽  
pp. A34.E329
Author(s):  
Ravi V. Shah ◽  
Annabel A. Chen-Tournoux ◽  
Michael H. Picard ◽  
Roland RJ van Kimmenade ◽  
James L. Januzzi
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Galectin 3 ◽  
Cardiac Structure And Function ◽  
And Function ◽  
Long Term Mortality

scholarly journals Characteristics, Outcomes and Predictors of Long-Term Mortality for Patients Hospitalized for Acute Heart Failure: A Report From the Korean Heart Failure Registry

2011 ◽  
Vol 41 (7) ◽  
pp. 363 ◽  
Author(s):  
Dong-Ju Choi ◽  
Seongwoo Han ◽  
Eun-Seok Jeon ◽  
Myeong-Chan Cho ◽  
Jae-Joong Kim ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Long Term Mortality

scholarly journals Utility of plasma galectin-3 in predicting long-term mortality in patients with acute heart failure

2021 ◽  
Vol 8 (4) ◽  
pp. 4306-4314
Author(s):  
Hoang Van Sy ◽  
Dang Quang Toan ◽  
Ta Thi-Thanh Huong ◽  
Chau Ngoc Hoa ◽  
Tran Kim Trang
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Troponin I ◽  
All Cause Mortality ◽  
Galectin 3 ◽  
One Year ◽  
Time Of Admission ◽  
Long Term Mortality

Background: Several studies have investigated Galectin-3 as a promising biomarker for predicting the short-term and long-term mortality of patients with acute heart failure. This study aimed to examine the usefulness of plasma galectin-3 at the time of admission in predicting long-term mortality in Vietnamese patients with acute heart failure (AHF). Methods: We carried out a cohort study including 117 patients consecutively diagnosed with acute heart failure in a single cardiology department. Plasma galectin-3 and other biomarkers were measured at the time of admission. The patient’s clinical and analytical characteristics were recorded. The main endpoint was one-year all-cause mortality. Results: There were six patients (5%) lost to follow-up and 59 patients (53.2%) reaching primary outcome within one year after ‎hospital admission.‎ The median plasma galectin-3 level (ng/mL) in patients with acute heart failure was 34.6 (26.7 – 44.1). Plasma galectin-3 in the alive group was significantly higher than that in the deceased group at one-year follow-up. In predicting one-year all-cause mortality, galectin-3 had an area under the curve (AUC) of 0.71 (95% confidence interval (CI), 0.62 – 0.81) representing a good prognostic factor while brain natriuretic peptide (BNP) and troponin I were inferior to galectin-3 with an AUC of 0.69 (95% CI, 0.59 – 0.79) and 0.63 (95% CI, 0.53 – 0.74), respectively. The optimal cut-off value for galectin-3 was 40.75 ng/mL with a sensitivity of 50.1% and a specificity of 88.5%. In a multivariate model, patients with galectin-3 levels > 40.75 ng/mL had a hazard ratio (HR) of 2.8 (95% CI, 1.5 – 5; p = 0.001). The best prediction model was the combined model of galectin-3 and BNP, yielding an AUC of 0.78 (95% CI, 0.70 – 0.86; p < 0.001). Conclusions: Our study suggested that galectin-3 levels could predict long-term all-cause mortality in patients with acute heart failure with a good prognostic capacity. Combining galectin-3 and BNP could bring up a better risk-stratification.

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