Effects of transcranial direct current stimulation (tDCS) on binge-eating disorder

2016 ◽  
Vol 49 (10) ◽  
pp. 930-936 ◽  
Author(s):  
Emilee E. Burgess ◽  
Maria D. Sylvester ◽  
Kathryn E. Morse ◽  
Frank R. Amthor ◽  
Sylvie Mrug ◽  
...  
2018 ◽  
Vol 40 (5) ◽  
pp. 487-490 ◽  
Author(s):  
Vanteemar S. Sreeraj ◽  
Manjunath Masali ◽  
Venkataram Shivakumar ◽  
Anushree Bose ◽  
Ganesan Venkatasubramanian

2020 ◽  

Introduction and Objectives: This study aimed to investigate the effect of transcranial direct current stimulation (tDCS) on food craving, attention bias to food, and cognitive flexibility in people with an eating disorder. Method: This is a pilot study with pre-test and post-test design and a control group. The study population consisted of 40 persons with an eating disorder who were purposefully selected using Binge Eating Scale, General Health Questionnaire, and clinical interview based on DSM-5 criteria. The participants were randomly divided into experimental and control groups. A pre-test was performed using a craving questionnaire, cognitive flexibility questionnaire, and food bias assessment tool based on the dot-prob paradigm. The intervention consisted of 10 sessions of two milliampere tDCS in the dorsolateral prefrontal cortex (DLPFC) area. Data analysis was conducted using SPSS software (version 23) through multivariate analysis of covariance. Results: Based on the obtained results, tDCS treatment had a significant effect on food bias, cognitive flexibility, and food craving in people with overeating disorder (P≤0.05). Moreover, the results remained stable at the 45-day follow-up after the posttest. Conclusion: Based on the results, the tDCS method along with other major therapeutic and psychological interventions can be effective in binge eating disorder. Therefore, the tDCS method can be promising and helpful as a suitable treatment modality with few side effects along with other major therapeutic interventions for patients with binge eating disorders.


BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e030023 ◽  
Author(s):  
Gemma Gordon ◽  
Timo Brockmeyer ◽  
Ulrike Schmidt ◽  
Iain C Campbell

IntroductionBinge eating disorder (BED) is a common mental disorder, closely associated with obesity. Existing treatments are only moderately effective with high relapse rates, necessitating novel interventions. This paper describes the rationale for, and protocol of, a feasibility randomised controlled trial (RCT), evaluating the combination of transcranial direct current stimulation (tDCS) and a computerised cognitive training, namely approach bias modification training (ABM), in patients with BED who are overweight or obese. The aim of this trial is to obtain information that will guide decision-making and protocol development in relation to a future large-scale RCT of combined tDCS+ABM treatment in this group of patients, and also to assess the preliminary efficacy of this intervention.Methods and analysis66 participants with Diagnostic and Statistical Manual-5 diagnosis of BED and a body mass index (BMI) of ≥25 kg/m2will be randomly allocated to one of three groups: ABM+real tDCS; ABM+sham tDCS or a wait-list control group. Participants in both intervention groups will receive six sessions of ABM+real/sham tDCS over 3 weeks; engaging in the ABM task while simultaneously receiving bilateral tDCS to the dorsolateral prefrontal cortex. ABM is based on an implicit learning paradigm in which participants are trained to enact an avoidance behaviour in response to visual food cues. Assessments will be conducted at baseline, post-treatment (3 weeks) and follow-up (7 weeks post-randomisation). Feasibility outcomes assess recruitment and retention rates, acceptability of random allocation, blinding success (allocation concealment), completion of treatment sessions and research assessments. Other outcomes include eating disorder psychopathology and related neurocognitive outcomes (ie, delay of gratification and inhibitory control), BMI, other psychopathology (ie, mood), approach bias towards food and surrogate endpoints (ie, food cue reactivity, trait food craving and food intake).Ethics and disseminationThis study has been approved by the North West-Liverpool East Research Ethics Committee. Results will be published in peer-reviewed journals.Trial registration numberISRCTN35717198


2011 ◽  
Vol 59 (4) ◽  
pp. 267-274 ◽  
Author(s):  
Anja Hilbert

Zusammenfassung.Die Klassifikation von Essstörungen steht im Zentrum aktuellen Forschungsinteresses. Gerade relativ rezente diagnostische Kategorien wie die Binge-Eating- oder Essanfallsstörung (Binge Eating Disorder, BED) und diagnostische Hauptmerkmale wie Essanfälle bedürfen im Zuge der Überarbeitungen des DSM einer Überprüfung. In dem vorliegenden Artikel werden zunächst die für das DSM-V vorgeschlagenen Veränderungen der diagnostischen Kriterien der BED und anderer Essstörungen beschrieben. An­schließend wird das Essanfallsmerkmal der Größe der verzehrten Nahrungsmenge in einer Forschungsübersicht hinsichtlich seiner klinischen Relevanz für die BED betrachtet. Dabei zeigt sich, dass sowohl objektive als auch subjektive Essanfälle psychopathologisch relevant sind. Jedoch sind objektive Essanfälle aufgrund ihrer Assoziation mit einem geringeren Behandlungserfolg, einer größeren residualen Symptomatik und vermehrten Rückfalltendenzen das vergleichsweise stringentere Erfolgskriterium in der Therapieerfolgsforschung der BED. Vor diesem Hintergrund erscheint es für die BED zentral, neben objektiven Essanfällen zusätzlich auch subjektive Essanfälle zu erfassen. Für das DSM-V wird empfohlen, ein Schema zu entwerfen, um das Auftreten und die Häufigkeit dieser Formen von Essanfällen für die BED sowie für andere klinische und subklinische Formen von Essanfällen systematisch zu erheben. Eine sorgfältige Erfassung der Essanfallsgröße in Studien zur Psychopathologie, zum Verlauf und zur Behandlung, wird es erlauben, die klinische Relevanz dieses Merkmals über das Essstörungsspektrum hinweg weiter zu klären.


2018 ◽  
Vol 127 (6) ◽  
pp. 548-558 ◽  
Author(s):  
Eva Naumann ◽  
Jennifer Svaldi ◽  
Tanja Wyschka ◽  
Markus Heinrichs ◽  
Bernadette von Dawans

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