scholarly journals The association of anxiety disorders and obsessive compulsive personality disorder with anorexia nervosa: Evidence from a family study with discussion of nosological and neurodevelopmental implications

2007 ◽  
Vol 40 (S3) ◽  
pp. S46-S51 ◽  
Author(s):  
Michael Strober ◽  
Roberta Freeman ◽  
Carlyn Lampert ◽  
Jane Diamond
Keyword(s):  
Anorexia Nervosa ◽  
Personality Disorder ◽  
Anxiety Disorders ◽  
Family Study ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Personality Disorder

Nature Against Nurture: Calcification in the Right Thalamus in a Young Man with Anorexia Nervosa and Obsessive-Compulsive Personality Disorder

CNS Spectrums ◽  
2008 ◽  
Vol 13 (10) ◽  
pp. 906-910 ◽  
Author(s):  
Rupert Conrad ◽  
Ingo Wegener ◽  
Franziska Geiser ◽  
Katrin Imbierowicz ◽  
Reinhard Liedtke
Keyword(s):  
Anorexia Nervosa ◽  
Weight Gain ◽  
Personality Disorder ◽  
Childhood And Adolescence ◽  
Obsessive Compulsive ◽  
Dorsomedial Nucleus ◽  
Life Event ◽  
The Right ◽  
Obsessive Compulsive Personality Disorder ◽  
Induce Weight Gain

ABSTRACTThis report describes the case of a young man with a large calcification in the right thalamus that was first diagnosed at 9 years of age. Case history reveals specific eating rituals and other obsessive-compulsive personality traits during the patient's childhood and adolescence, fulfilling diagnostic criteria of obsessive-compulsive personality disorder. After a critical life event the patient develops anorexia nervosa. We suggest that our case and further literature provide evidence for an involvement of specific thalamic structures, such as the dorsomedial nucleus, in the development of anorexia nervosa. Furthermore, the treatment of the patient by a combined psychotherapeutic and pharmacotherapeutic approach is described. We focus on the beneficial effect of the atypical antipsychotic olanzapine, which can induce weight gain by an increase of leptin levels.

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