scholarly journals ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis

2018 ◽  
Vol 247 (6) ◽  
pp. 854-866 ◽  
Author(s):  
Koushik K. Das ◽  
Steffen Heeg ◽  
Jason R. Pitarresi ◽  
Maximilian Reichert ◽  
Basil Bakir ◽  
...  
Keyword(s):  
Ductal Morphogenesis

scholarly journals CITED1 homozygous null mice display aberrant pubertal mammary ductal morphogenesis

Oncogene ◽  
2005 ◽  
Vol 25 (10) ◽  
pp. 1532-1542 ◽  
Author(s):  
J Howlin ◽  
J McBryan ◽  
S Napoletano ◽  
T Lambe ◽  
E McArdle ◽  
...  
Keyword(s):  
Ductal Morphogenesis

scholarly journals Stromal Cells Are Critical Targets in the Regulation of Mammary Ductal Morphogenesis by Parathyroid Hormone-Related Protein

1998 ◽  
Vol 203 (1) ◽  
pp. 75-89 ◽  
Author(s):  
Maureen E. Dunbar ◽  
Peter Young ◽  
Jian-Ping Zhang ◽  
James McCaughern-Carucci ◽  
Beate Lanske ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Stromal Cells ◽  
Related Protein ◽  
Ductal Morphogenesis ◽  
Parathyroid Hormone Related Protein

scholarly journals FOXA1 is an essential determinant of ER  expression and mammary ductal morphogenesis

Development ◽  
2010 ◽  
Vol 137 (12) ◽  
pp. 2045-2054 ◽  
Author(s):  
G. M. Bernardo ◽  
K. L. Lozada ◽  
J. D. Miedler ◽  
G. Harburg ◽  
S. C. Hewitt ◽  
...  
Keyword(s):  
Ductal Morphogenesis ◽  
Er Expression

794d The ETS Transcription Factor ETV5 Regulates Ductal Morphogenesis and Differentiation in Association With SOX9

2014 ◽  
Vol 146 (5) ◽  
pp. S-138
Author(s):  
Steffen Heeg ◽  
Koushik K. Das ◽  
Maximilian Reichert ◽  
Shigetsugu Takano ◽  
Basil Bakir ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Ductal Morphogenesis ◽  
Ets Transcription Factor

scholarly journals Adipocyte derived paracrine mediators of mammary ductal morphogenesis controlled by retinoic acid receptors

2011 ◽  
Vol 349 (2) ◽  
pp. 125-136 ◽  
Author(s):  
Christine V. Marzan ◽  
Tara S. Kupumbati ◽  
Silvina P. Bertran ◽  
TraceyAnn Samuels ◽  
Boris Leibovitch ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Retinoic Acid Receptors ◽  
Ductal Morphogenesis

scholarly journals The miR-200 family in normal mammary gland development

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Majesta J. Roth ◽  
Roger A. Moorehead
Keyword(s):  
Mammary Tumor ◽  
Mammalian Species ◽  
Late Pregnancy ◽  
Mammary Glands ◽  
Mammary Development ◽  
Normal Mammary Gland ◽  
Ductal Morphogenesis ◽  
Mammary Tumor Growth ◽  
Pregnancy And Lactation ◽  
The Impact

AbstractThe miR-200 family of microRNAs plays a significant role in inhibiting mammary tumor growth and progression, and its members are being investigated as therapeutic targets. Additionally, if future studies can prove that miR-200s prevent mammary tumor initiation, the microRNA family could also offer a preventative strategy. Before utilizing miR-200s in a therapeutic setting, understanding how they regulate normal mammary development is necessary. No studies investigating the role of miR-200s in embryonic ductal development could be found, and only two studies examined the impact of miR-200s on pubertal ductal morphogenesis. These studies showed that miR-200s are expressed at low levels in virgin mammary glands, and elevated expression of miR-200s have the potential to impair ductal morphogenesis. In contrast to virgin mammary glands, miR-200s are expressed at high levels in mammary glands during late pregnancy and lactation. miR-200s are also found in the milk of several mammalian species, including humans. However, the relevance of miR-200s in milk remains unclear. The increase in miR-200 expression in late pregnancy and lactation suggests a role for miR-200s in the development of alveoli and/or regulating milk production. Therefore, studies investigating the consequence of miR-200 overexpression or knockdown are needed to identify the function of miR-200s in alveolar development and lactation.

Sign in / Sign up

Export Citation Format

Share Document