scholarly journals Regulation of Tbx22 during facial and palatal development

2010 ◽  
Vol 239 (11) ◽  
pp. 2860-2874 ◽  
Author(s):  
Alisa Fuchs ◽  
Andrea Inthal ◽  
David Herrmann ◽  
Shuofei Cheng ◽  
Mitsushiro Nakatomi ◽  
...  
Keyword(s):  
Palatal Development

Cleft palate induction in hamster fetuses by glucocorticoid hormones and their synthetic analogues

Development ◽  
1976 ◽  
Vol 36 (1) ◽  
pp. 101-108
Author(s):  
Ravindra M. Shah ◽  
Alan Kilistoff
Keyword(s):  
Cleft Palate ◽  
Growth Inhibition ◽  
Fetal Growth ◽  
Glucocorticoid Hormones ◽  
Synthetic Analogues ◽  
Total Frequency ◽  
Different Types ◽  
Palatal Development ◽  
Different Doses

The effect of prenatal administration of different doses of cortisone, corticosterone, dexamethasone, triamcinolone and prednisolone on the fetus and its palatal development was studied. All the glucocorticoids, except cortisone, produced cleft palate in the fetuses. Both the total frequency and morphologically different types of cleft palate were related to the dose of the teratogen. Triamcinolone appeared to be more potent than other glucocorticoid in inducing cleft palate. An association was noted between fetal growth inhibition, the dose of the teratogen and the frequency and type of cleft palate.

scholarly journals Intracellular Signaling Pathway Activation via TGF-β Differs in the Anterior and Posterior Axis During Palatal Development

2016 ◽  
Vol 25 (2) ◽  
pp. 195-204
Author(s):  
Arisa Higa ◽  
Kyoko Oka ◽  
Michiko Kira-Tatsuoka ◽  
Shougo Tamura ◽  
Satoshi Itaya ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Intracellular Signaling ◽  
Intracellular Signaling Pathway ◽  
Pathway Activation ◽  
Palatal Development

Human palatal development, in vitro

1977 ◽  
Vol 60 (6) ◽  
pp. 931
Author(s):  
David Wood ◽  
A. N. Goss
Keyword(s):  
Palatal Development ◽  
Development In Vitro

scholarly journals Tbx1 regulates oral epithelial adhesion and palatal development

2012 ◽  
Vol 21 (11) ◽  
pp. 2524-2537 ◽  
Author(s):  
Noriko Funato ◽  
Masataka Nakamura ◽  
James A. Richardson ◽  
Deepak Srivastava ◽  
Hiromi Yanagisawa
Keyword(s):  
Palatal Development ◽  
Oral Epithelial

The teratogenic effects of hydrocortisone on palatal development in the hamster

Development ◽  
1976 ◽  
Vol 35 (1) ◽  
pp. 213-224
Author(s):  
Ravindra M. Shah ◽  
Anthony A. Travill
Keyword(s):  
Cleft Palate ◽  
Close Association ◽  
Fetal Growth Retardation ◽  
Placental Barrier ◽  
Teratogenic Effects ◽  
Different Types ◽  
Palatal Development ◽  
Two Peaks ◽  
Different Doses ◽  
Hydrocortisone Treatment

The effect of different doses of hydrocortisone, administered at various times during gestation, on the fetal hamster and its palatal development was studied. Both the frequency of cleft palate and that of resorption depended upon the dose of hydrocortisone and the time of its administration. Two peaks in the incidence of cleft palate were observed, which appeared to be due to inhibition of different events. Incidence of morphologically different types of cleft palate was related to the doses and gestational time of hydrocortisone treatment. A close association was observed between the frequency of cleft palate and fetal growth retardation and between the latter and the dose and time of drug administration. It was suggested that maternal physiology and the placental barrier may play a crucial role in cleft palate induction.

Morphological study of cleft palate development in 5-fluorouracil-treated hamster fetuses

Development ◽  
1980 ◽  
Vol 57 (1) ◽  
pp. 119-128
Author(s):  
Ravindra M. Shah ◽  
David T. W. Wong
Keyword(s):  
Cleft Palate ◽  
Gestational Age ◽  
Horizontal Plane ◽  
Morphological Study ◽  
Fetal Weight ◽  
Rating System ◽  
Crown Rump Length ◽  
Palate Development ◽  
Palatal Development

Morphogenesis of palate was studied in normal and 5-fluorouracil-treated hamster fetuses. The results showed that normal palatal development was completed between days 12 and 13 of gestation. In 5-fluorouracil-assaulted palate the reorientation of shelves from a vertical to horizontal plane was delayed. Crown-rump length, gestational age and fetal weight were reliable predictors of the stages of normal palatal development, whereas the morphological rating system was not. Following 5-fiuorouracil treatment, however, crown-rump length, weight and morphological rating were poor indicators of the stage of palatal development.

Effects of Anti-Inflammatory Steroids on Mouse Embryonic Movements During Palatal Development

1975 ◽  
Vol 54 (6) ◽  
pp. 1200-1206 ◽  
Author(s):  
Bruce E. Walker ◽  
Joan Quarles
Keyword(s):  
Mouse Embryos ◽  
Strain Mouse ◽  
Palatal Development ◽  
Anti Inflammatory

The frequency of spontaneous embryonic muscular movements was recorded for embryos from mice treated with cortisone or triamcinolone. Movement was significantly reduced in A/J strain mouse embryos exposed to these anti-inflammatory agents. Cleft palates induced by the drugs may originate from failure of the embryonic tongue to be withdrawn from between the palatine shelves.

Palatal Development inTwirlerMice

2001 ◽  
Vol 38 (6) ◽  
pp. 622-628 ◽  
Author(s):  
Siew-Ging Gong ◽  
Rachel L. Eulenberg
Keyword(s):  
Palatal Development

Palatal Changes after Lip Surgery in Different Types of Cleft Lip and Palate

1994 ◽  
Vol 31 (5) ◽  
pp. 376-384 ◽  
Author(s):  
Gem J.C. Kramer ◽  
Jan B. Hoeksma ◽  
Birte Prahl-Andersen
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Alveolar Region ◽  
Alveolar Cleft ◽  
Nasal Side ◽  
Different Types ◽  
Palatal Development ◽  
Depth Reduction

This study concerns palatal development during 6 months following primary lip closure. The sample consisted of 75 children with different forms of cleft lip and palate and 51 noneleft children. The palate was measured at 3 months of age, just before lip surgery, after surgery at 6 months, and again at 9 months of age. The results showed that lip closure has a strong effect in the anterior alveolar region. This effect was restricted to 3 months after surgery. The changes in complete clefts were more explicit than in incomplete cleft forms. Furthermore, the data showed that arch depth reduction due to lip surgery was compensated for by continued anteroposterior palatal growth. Early orthopedics appeared to prevent major palatal collapse immediately after lip surgery. Finally simultaneous closure of the alveolar cleft at the nasal side resulted in continued reduction of anterior cleft width.

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