scholarly journals Tubular sprouting as a mode of vascular formation in a colonial ascidian (tunicata)

2007 ◽  
Vol 236 (3) ◽  
pp. 719-731 ◽  
Author(s):  
Fabio Gasparini ◽  
Fabrizio Longo ◽  
Lucia Manni ◽  
Paolo Burighel ◽  
Giovanna Zaniolo
Keyword(s):  
Colonial Ascidian ◽  
Vascular Formation

The Embryonic Angiogenic Factor Del1 Accelerates Tumor Growth by Enhancing Vascular Formation

2002 ◽  
Vol 64 (1) ◽  
pp. 148-161 ◽  
Author(s):  
Yoshikazu Aoka ◽  
Frances L. Johnson ◽  
Kalyani Penta ◽  
Ken-ichi Hirata ◽  
Chiaki Hidai ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Angiogenic Factor ◽  
Vascular Formation

scholarly journals Cardiac-specific Activation of Signal Transducer and Activator of Transcription 3 Promotes Vascular Formation in the Heart

2001 ◽  
Vol 277 (8) ◽  
pp. 6676-6681 ◽  
Author(s):  
Tomoaki Osugi ◽  
Yuichi Oshima ◽  
Yasushi Fujio ◽  
Masanobu Funamoto ◽  
Atsuko Yamashita ◽  
...  
Keyword(s):  
Signal Transducer ◽  
Transcription 3 ◽  
Vascular Formation

scholarly journals Balancing selection on allorecognition genes in the colonial ascidian Botryllus schlosseri

2017 ◽  
Vol 69 ◽  
pp. 60-74 ◽  
Author(s):  
Marie L. Nydam ◽  
Emily E. Stephenson ◽  
Claire E. Waldman ◽  
Anthony W. De Tomaso
Keyword(s):  
Balancing Selection ◽  
Botryllus Schlosseri ◽  
Colonial Ascidian

scholarly journals Significant polar vasculosis in a patient with a 30-year history of type 2 diabetes

2019 ◽  
Vol 2019 ◽  
Author(s):  
Yasuhiro Oda ◽  
Masayuki Yamanouchi ◽  
Hiroki Mizuno ◽  
Rikako Hiramatsu ◽  
Tatsuya Suwabe ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Endothelial Damage ◽  
Diabetic Patients ◽  
List Type ◽  
History Of ◽  
Intraglomerular Pressure ◽  
Vascular Formation

Summary We report the renal histology of a 66-year-old man with hypertension, cardiovascular disease, and a 30-year history of type 2 diabetes mellitus with proliferative diabetic retinopathy, diabetic neuropathy, and diabetic foot status post toe amputation. Urinary protein excretion was 1.4 g/gCr, serum creatinine level 0.86 mg/dL, estimated glomerular filtration rate 69 mL/min/1.73 m2, and HbA1c 13–15%, despite using insulin. Light microscopy showed global glomerulosclerosis in 37% of the glomeruli, but the remaining glomeruli were intact. Significant polar vasculosis was present, while arteriolar sclerosis was mild. Electron microscopy revealed a thickened glomerular basement membrane, which is compatible with the early stage of diabetic glomerulopathy. The presented case was unique because glomerular changes seen typically in diabetes were not seen in the patient, despite the long-standing history of diabetes and diabetic comorbidities, while prominent polar vasculosis was found. Polar vascular formation helps preserve the glomeruli by allowing hyperosmotic blood bypass the glomeruli; this decreases intraglomerular pressure and minimizes glomerular endothelial damage. Learning points: A 66-year-old man with a 30-year history of type 2 diabetes mellitus with poor glycemic control underwent renal biopsy, which showed scarce glomerular changes typically seen in diabetic kidney disease and instead revealed significant polar vasculosis. Past studies demonstrated that the increased small vessels around the vascular hilus in diabetic patients originated from the afferent arterioles and drained into the peritubular capillaries. Polar vascular formation may preserve glomerular function by allowing the blood flow to bypass the glomeruli and decreasing the intraglomerular pressure, which minimizes endothelial damage of the glomerular tufts.

scholarly journals Long-term monitoring data logs of a recirculating artificial seawater based colonial ascidian aquaculture

Data in Brief ◽  
2021 ◽  
Vol 38 ◽  
pp. 107372
Author(s):  
Marta K. Wawrzyniak ◽  
Lluìs Albert Matas Serrato ◽  
Simon Blanchoud
Keyword(s):  
Artificial Seawater ◽  
Monitoring Data ◽  
Colonial Ascidian ◽  
Long Term Monitoring ◽  
Term Monitoring

scholarly journals Immunotoxicity in Ascidians: Antifouling Compounds Alternative to Organotins—V. the Case of Dichlofluanid

2020 ◽  
Vol 8 (6) ◽  
pp. 396
Author(s):  
Francesca Cima ◽  
Roberta Varello
Keyword(s):  
Marine Invertebrates ◽  
Zinc Pyrithione ◽  
Short Term ◽  
Colonial Ascidian ◽  
Antifouling Paints ◽  
Glutathione Oxidation ◽  
Defence Responses ◽  
Sediment Interface ◽  
Sublethal Concentrations

Dichlofluanid has long been employed as a fungicide in agriculture and has been massively introduced in antifouling paints for boat hulls over the last two decades. One of the most important toxic effects of antifoulants is represented by immunosuppression in marine invertebrates, which can be analysed in vitro with a number of short-term toxicity assays on haemocytes. Among bioindicators, the colonial ascidian Botryllus schlosseri is a useful candidate; it is a filter-feeding organism living in the water-sediment interface that is found worldwide and is sensitive to antifouling xenobiotics. Dichlofluanid adversely affects both immunocyte lines (phagocyte and cytotoxic lines) after exposure to sublethal concentrations. At 0.05 μM (16.65 μg/L), dichlofluanid induced haemocyte apoptosis and cell shrinkage with a decrease in both motility and phagocytosis. At the lowest concentration (0.01 μM, 3.33 μg/L), inhibition of pivotal enzymatic activities of phagocytes and cytotoxic cells occurred. At the highest concentration (0.1 μM, 33.3 μg/L), dichlofluanid increased glutathione oxidation, leading to stress conditions. The effects of dichlofluanid on immune defence responses are similar to those of organometal-based antifoulants (i.e., organotin compounds and zinc pyrithione), and its use in coastal areas requires attention.

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