scholarly journals Evolution and development of Hertwig's epithelial root sheath

2006 ◽  
Vol 235 (5) ◽  
pp. 1167-1180 ◽  
Author(s):  
Xianghong Luan ◽  
Yoshihiro Ito ◽  
Thomas G.H. Diekwisch
Keyword(s):  
Hertwig’S Epithelial Root Sheath ◽  
Evolution And Development ◽  
Root Sheath

Immortalized Hertwig's epithelial root sheath cell line works as model for epithelial–mesenchymal interaction during tooth root formation

2019 ◽  
Vol 235 (3) ◽  
pp. 2698-2709 ◽  
Author(s):  
Sicheng Zhang ◽  
Xuebing Li ◽  
Shikai Wang ◽  
Yan Yang ◽  
Weihua Guo ◽  
...  
Keyword(s):  
Cell Line ◽  
Root Formation ◽  
Tooth Root ◽  
Sheath Cell ◽  
Hertwig’S Epithelial Root Sheath ◽  
Root Sheath

scholarly journals Development of immortalized Hertwig’s epithelial root sheath cell lines for cementum and dentin regeneration

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Xuebing Li ◽  
Sicheng Zhang ◽  
Zirui Zhang ◽  
Weihua Guo ◽  
Guoqing Chen ◽  
...  
Keyword(s):  
Cell Lines ◽  
Sheath Cell ◽  
Hertwig’S Epithelial Root Sheath ◽  
Root Sheath ◽  
Dentin Regeneration

Developmental Properties of the Hertwig’s Epithelial Root Sheath in Mice

2004 ◽  
Vol 83 (9) ◽  
pp. 688-692 ◽  
Author(s):  
H. Yamamoto ◽  
S.-W. Cho ◽  
E.-J. Kim ◽  
J.-Y. Kim ◽  
N. Fujiwara ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Culture System ◽  
Root Formation ◽  
Expression Patterns ◽  
Tooth Root ◽  
Comprehensive Model ◽  
Hertwig’S Epithelial Root Sheath ◽  
Root Sheath ◽  
In Vitro Culture System

Hertwig’s epithelial root sheath (HERS) plays an important role in tooth root formation. In this study, we examined root formation of the first molar in mice, focusing on cell proliferation, cell death, cell migration, and the expression patterns of the signaling molecules, including glycoproteins and proteoglycans between PN8 and PN26. The number of HERS cells decreased during root formation, although HERS retained total length until PN15. The migration of HERS cells did not occur during root formation. Moreover, the immunopositive reaction of laminin beta-3 and syndecan-1 in HERS indicates that both cell adhesion and cell proliferation are essential for HERS development. Bmp-2, Bmp-4, and Msx-2 were expressed in HERS cells during root formation. We also developed an in vitro culture system for investigating the periodontium and suggest that this system provides an excellent vehicle for full exploration, and hence improved understanding, of the development and regeneration of the periodontium. Together, our results provide a comprehensive model describing the morphogenesis of early root development in vertebrates.

scholarly journals Establishment of Hertwig’s Epithelial Root Sheath/Epithelial Rests of Malassez Cell Line from Human Periodontium

2014 ◽  
Vol 37 (7) ◽  
pp. 562-567 ◽  
Author(s):  
Hyun Nam ◽  
Ji-Hye Kim ◽  
Jae-Won Kim ◽  
Byoung-Moo Seo ◽  
Joo-Cheol Park ◽  
...  
Keyword(s):  
Cell Line ◽  
Hertwig’S Epithelial Root Sheath ◽  
Epithelial Rests Of Malassez ◽  
Root Sheath
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