Oral fluid for workplace drug testing: Laboratory implementation

2011 ◽  
Vol 4 (2) ◽  
pp. 89-93 ◽  
Author(s):  
Christine Moore
Keyword(s):  
Drug Testing ◽  
Oral Fluid ◽  
Testing Laboratory ◽  
Workplace Drug Testing

scholarly journals European guidelines for workplace drug testing in oral fluid

2017 ◽  
Vol 10 (3) ◽  
pp. 402-415 ◽  
Author(s):  
Michaela Brcak ◽  
Olof Beck ◽  
Tessa Bosch ◽  
Duncan Carmichael ◽  
Nadia Fucci ◽  
...  
Keyword(s):  
Drug Testing ◽  
Oral Fluid ◽  
European Guidelines ◽  
Workplace Drug Testing

Guidelines for European workplace drug testing in oral fluid

2011 ◽  
Vol 3 (5) ◽  
pp. 269-276 ◽  
Author(s):  
Gail Cooper ◽  
Christine Moore ◽  
Claire George ◽  
Simona Pichini
Keyword(s):  
Drug Testing ◽  
Oral Fluid ◽  
Workplace Drug Testing

scholarly journals On-Site Test for Cannabinoids in Oral Fluid

2012 ◽  
Vol 58 (10) ◽  
pp. 1418-1425 ◽  
Author(s):  
Nathalie A Desrosiers ◽  
Dayong Lee ◽  
David M Schwope ◽  
Garry Milman ◽  
Allan J Barnes ◽  
...  
Keyword(s):  
Test Performance ◽  
Drug Testing ◽  
Oral Fluid ◽  
Diagnostic Sensitivity ◽  
Driving Under The Influence ◽  
Sample Collection ◽  
Institutional Review ◽  
Noninvasive Sample ◽  
Site Test ◽  
Workplace Drug Testing

Abstract BACKGROUND Oral fluid (OF) testing offers noninvasive sample collection for on-site drug testing; however, to date, test performance for Δ9-tetrahydrocannabinol (THC) detection has had unacceptable diagnostic sensitivity. On-site tests must accurately identify cannabis exposure because this drug accounts for the highest prevalence in workplace drug testing and driving under the influence of drugs (DUID) programs. METHODS Ten cannabis smokers (9 males, 1 female) provided written informed consent to participate in this institutional review board–approved study and smoked 1 6.8%-THC cigarette ad libitum. OF was collected with the Draeger DrugTest® 5000 test cassette and Quantisal™ device 0.5 h before and up to 22 h after smoking. Test cassettes were analyzed within 15 min (n = 66), and Quantisal GC-MS THC results obtained within 24 h. Final THC detection times and test performances were assessed at different cannabinoid cutoffs. RESULTS Diagnostic sensitivity, diagnostic specificity, and efficiency at DrugTest 5000's 5 μg/L screening cutoff and various THC confirmation cutoffs were 86.2–90.7, 75.0–77.8, and 84.8–87.9%, respectively. Last detection times were >22 h, longer than previously suggested. Confirmation of 11-nor-9-carboxy-THC, absent in THC smoke, minimized the potential for passive OF contamination and still provided 22-h windows of detection, appropriate for workplace drug testing, whereas confirmation of cannabidiol, and/or cannabinol yielded shorter 6-h windows of detection, appropriate for DUID OF testing. CONCLUSIONS The DrugTest 5000 on-site device provided high diagnostic sensitivity for detection of cannabinoid exposure, and the selection of OF confirmation analytes and cutoffs provided appropriate windows of detection to meet the goals of different drug testing programs.

Seven years of workplace drug testing in Italy: A systematic review and meta-analysis

2017 ◽  
Vol 9 (6) ◽  
pp. 844-852 ◽  
Author(s):  
Gian Luca Rosso ◽  
Cristina Montomoli ◽  
Luca Morini ◽  
Stefano M. Candura
Keyword(s):  
Systematic Review ◽  
Drug Testing ◽  
Meta Analysis ◽  
Workplace Drug Testing

scholarly journals The Characterization of Human Urine for Specimen Validity Determination in Workplace Drug Testing: A Review

2000 ◽  
Vol 24 (7) ◽  
pp. 579-588 ◽  
Author(s):  
J. D. Cook ◽  
Y. H. Caplan ◽  
C. P. LoDico ◽  
D. M. Bush
Keyword(s):  
Human Urine ◽  
Drug Testing ◽  
Workplace Drug Testing
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