Hematological changes following an Ironman triathlon: An antidoping perspective

2019 ◽  
Vol 11 (11-12) ◽  
pp. 1747-1754 ◽  
Author(s):  
Geoffrey D. Miller ◽  
Adam Beharry ◽  
Masaru Teramoto ◽  
Auriella Lai ◽  
Stuart E. Willick ◽  
...  
Keyword(s):  
Hematological Changes ◽  
Ironman Triathlon

CLINICAL AND LABORATORY PECULIARITIES OF WHOOPING COUGH IN CHILDREN OF DIFFERENT AGE GROUPS

2020 ◽  
Vol 99 (6) ◽  
pp. 98-104
Author(s):  
I.V. Babachenko ◽  
◽  
Y.V. Nesterova ◽  
N.V. Skripchenko ◽  
◽  
...  
Keyword(s):  
Whooping Cough ◽  
Severe Disease ◽  
Respiratory Rhythm ◽  
Age Groups ◽  
Low Frequency ◽  
Pertussis Infection ◽  
Group 2 ◽  
Sick Children ◽  
Hematological Changes ◽  
Group 1

Objective of the research: to present the clinical and laboratory peculiarities of modern whooping cough in hospitalized children of different ages. Materials and methods: сlinical and laboratory characteristics of whooping cough were analyzed in 88 hospitalized sick children aged 1 month to 18 years in groups of children: group 1 – children under 1 year old; group 2 – children 1–6 years old; group 3 – children 7–17 years old. DNA of causative agents of pertussis infection was isolated by PCR in nasopharyngeal swabs using a commercial kit AmpliSens®Bordetella multi-FL (Moscow). Results: children of group 1 in 90% (n=43) of cases were not vaccinated against whooping cough, severe forms were recorded in 17% (n=8) of children of the 1st year of life, and in 15% (n=7) – due to respiratory rhythm disturbances. The diagnosis was confirmed by PCR in 94% (n=45) of children, leukocytosis with lymphocytosis was detected in 81,5% (n=101). Along with hematological changes typical for whooping cough, 79% (n=38) of patients in the first year of life had thrombocytosis (>400×109/l), which was most pronounced in severe disease course 511,5 [425; 568,5]×109/l vs 421 [347; 505,5]×109/l; p<0,05, which has no tendency to decrease throughout the entire observation period and correlates with the level of leukocytes (rs=0,69; p<0,001). Patients over 7 years old in 88% (n=21) of cases were vaccinated against whooping cough, but 79% (n=27) hemograms had no characteristic changes, which, along with a low frequency of confirmation of the diagnosis by PCR 22% (n=4), made it difficult to diagnose whooping cough. Conclusion: children over 7 years of age may not have characteristic hematological changes and PCR diagnostics are insufficiently effective, which contributes to the spread of whooping cough in family foci.

ACUTE TOXICITY OF CERIUM DIOXIDE NANOPARTICLES

2019 ◽  
pp. 56-62
Author(s):  
N. V. Khodykina ◽  
L. P. Tochilkina ◽  
O. N. Novikova ◽  
M. S. Sroslov ◽  
A. Ya. Pocheptsov ◽  
...  
Keyword(s):  
Toxic Effect ◽  
Cerium Dioxide ◽  
Intraperitoneal Administration ◽  
Body Weight Loss ◽  
The Body ◽  
Prooxidant Effect ◽  
High Exposure ◽  
Abdominal Organs ◽  
Metabolic Imbalance ◽  
Hematological Changes

The resorptive effects of 0.01 M cerium nanodioxide sol upon single intraperitoneal administration to rats have been studied. The acute exposure to nanoparticles was found to have a dose-dependent general toxic effect on the body (weight loss, inflammatory changes in the abdominal organs, modification of individual behavior, hematological changes, metabolic imbalance), which develops on the background of POL activation. The prooxidant effect of cerium dioxide nanoparticles is demonstratively manifested at relatively high exposure levels (80–8 mg / kg). The threshold dose for the general toxic effect (Limch integr) is equal to 0.8 mg / kg.

scholarly journals Hematological Changes and Reference Intervals in Hanwoo Calves during the First 28 Weeks of Life

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1806
Author(s):  
Ui-Hyung Kim ◽  
Seung-Hwan Lee ◽  
Sang-Rae Cho ◽  
Sung-Sik Kang ◽  
Shil Jin ◽  
...  
Keyword(s):  
Hemoglobin Concentration ◽  
Reference Intervals ◽  
Mean Corpuscular Hemoglobin ◽  
Blood Cell Count ◽  
Platelet Volume ◽  
Adult Cattle ◽  
Male And Female ◽  
Analytic Process ◽  
Process Work ◽  
Hematological Changes

Hematological reference intervals must consider several parameters, including genotype, age, sex, management, and analytic process. Work is needed to evaluate hematological changes specifically in Hanwoo calves and according to calf sex. Therefore, in this study, we sought to confirm the complete blood cell count (CBC) reference intervals in Hanwoo calves, to monitor changes in hematologic values in Hanwoo calves from birth until 28 weeks of life, and to compare the hematologic values of male and female calves. A total of 35 male calves and 35 female calves was studied. Calf blood was sampled at multiple intervals from the time of birth until 28 weeks of age (including within 6 h of birth and at 2 days, 7 days, and 4 weeks and then at 4-week intervals through 28 weeks). In addition, blood samples were collected from 210 clinically healthy pregnant Hanwoo cows to establish CBC reference intervals for adult cattle. There were significant differences in the results of the cows and calves in all 14 parameters considered. The CBC reference intervals of the calves were wider than those of the cows in all parameters except mean corpuscular volume, mean corpuscular hemoglobin concentration, and mean platelet volume. We also identified differences from birth through 28 weeks between male and female calves at only some ages and some parameters. These results suggest that CBC reference intervals specific to Hanwoo calves are necessary for accurate diagnosis of calf diseases.

scholarly journals HEMATOLOGICAL PARAMETERS AND BODY COMPOSITION OF SOCCER PLAYERS

2018 ◽  
Vol 24 (3) ◽  
pp. 202-205 ◽  
Author(s):  
Allana Kelly Bussollaro ◽  
Barbara Nara de Freitas ◽  
Raíssa Maria Fadel ◽  
Gabriela Siqueira Lara ◽  
Priscila Dabaghi Barbosa ◽  
...  
Keyword(s):  
Body Composition ◽  
Serum Iron ◽  
Binding Capacity ◽  
Hematological Parameters ◽  
Soccer Players ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Level Of Evidence ◽  
Hematological Changes ◽  
Post Hoc

ABSTRACT Introduction: Soccer players may experience hematological changes that could be detrimental to their health status. In addition, inadequate body composition may impair performance. Objective: To assess body composition and hematological changes over a year in soccer players. Methods: A retrospective observational study was conducted. Age, weight, height, body composition, blood count, serum iron, serum ferritin, serum transferrin and total iron binding capacity data were collected from the athletes’ medical records in the months of January, May and August of 2015 and January of 2016. Body mass index was also calculated. For the statistical analyses, the Anova and post-hoc Tukey’s post-hoc tests were used for the quantitative variables and the Chi-square test for the qualitative variables. The significance level adopted was p<0.05. Results: Data were evaluated for 51 athletes with a mean age of 23.53 ± 3.11 years, 77.10 ± 6.56 kg, 1.80 ± 0.07 and 15.6 ± 2.89% body fat (BF). We observed significant (p<0.05) changes in mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, cell size and eosinophils during the period evaluated. Among the athletes, 21.6% had decreased hematocrit levels and 3.9% had hemoglobin levels below the reference range. A BF% greater than 16% was significantly related to serum iron depletion (p = 0.01). Conclusion: Small significant hematological changes during the competitive year were observed, but without significant changes in body composition. Level of Evidence III; Study of nonconsecutive patients; without consistently applied reference ‘‘gold’’ standard.

Cervical Injury In a Age Group Ironman Triathlon Athlete

2015 ◽  
Vol 47 ◽  
pp. 567-568
Author(s):  
Daniel T. de Oliveira ◽  
Everton Q. Fiebig ◽  
Juliano F. Silva ◽  
Daniel S. Carvalho
Keyword(s):  
Age Group ◽  
Cervical Injury ◽  
Ironman Triathlon
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