scholarly journals Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho - and meta - positional isomers

2018 ◽  
Vol 10 (9) ◽  
pp. 1404-1416 ◽  
Author(s):  
Gavin McLaughlin ◽  
Michael H. Baumann ◽  
Pierce V. Kavanagh ◽  
Noreen Morris ◽  
John D. Power ◽  
...  
Keyword(s):  
Positional Isomers ◽  
Psychoactive Substance ◽  
New Psychoactive Substance ◽  
Monoamine Transporter ◽  
Analytical Characterization

scholarly journals Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and itsN-methoxy positional isomer,N-methoxymephedrone

2016 ◽  
Vol 9 (3) ◽  
pp. 358-368 ◽  
Author(s):  
Gavin McLaughlin ◽  
Noreen Morris ◽  
Pierce V. Kavanagh ◽  
John D. Power ◽  
Geraldine Dowling ◽  
...  
Keyword(s):  
Positional Isomer ◽  
Psychoactive Substance ◽  
New Psychoactive Substance ◽  
Monoamine Transporter

scholarly journals Synthesis, characterization, and monoamine transporter activity of the new psychoactive substance 3′,4′-methylenedioxy-4-methylaminorex (MDMAR)

2014 ◽  
Vol 7 (7) ◽  
pp. 555-564 ◽  
Author(s):  
Gavin McLaughlin ◽  
Noreen Morris ◽  
Pierce V. Kavanagh ◽  
John D. Power ◽  
Brendan Twamley ◽  
...  
Keyword(s):  
Psychoactive Substance ◽  
New Psychoactive Substance ◽  
Monoamine Transporter

Effect of Unobserved Contextual Factors on the Prevalence of New Psychoactive Substance Use in Thailand

2021 ◽  
Vol 104 (2) ◽  
pp. 252-259
Keyword(s):  
Elementary Education ◽  
Structured Interview ◽  
New Psychoactive Substances ◽  
Cluster Sampling ◽  
Psychoactive Substance ◽  
New Psychoactive Substance ◽  
Binary Logistic Regression Model ◽  
Cross Sectional ◽  
Cluster Environment ◽  
The Impact

Objective: To explore the associations of characteristics of the cluster environment with new psychoactive substances (NPS) use in Thailand. Materials and Methods: A cross-sectional study was done on 30,411 Thai people, stratified in multi-stage cluster sampling. Trained interviewers conducted a semi-structured interview in 2016. A multilevel binary logistic regression model was employed to estimate the effects of the cluster environment on the NPS use. Results: NPS was widely used. The past month prevalence was 13.6%, and habitual use was 4.4%. Clustering significantly affects the spread of NPS use. Controlling for cluster effects, a likelihood of current NPS use was associated with elementary education, occupation, and reported health problems. While a higher likelihood of habitual NPS use was associated with elementary education, employed, and perceived mental health problem. Conclusion: NPS use was influenced by characteristics of the cluster environment. Therefore, demand reduction strategies should be designed based on a consideration of the impact of cluster context on NPS use behaviors. Keywords: Cluster effect, New psychoactive substance, NPS, Thailand

Gamma-Butyrolactone Overdose Potentially Complicated by Co-Ingestion of Industrial Solvent N-Methyl-2-Pyrrolidone

2020 ◽  
Author(s):  
Jonathan Melamed ◽  
Roy Gerona ◽  
Paul D Blanc ◽  
Paul Takamoto ◽  
Stephanie Conner ◽  
...  
Keyword(s):  
Substance Use ◽  
Psychoactive Substance ◽  
New Psychoactive Substance ◽  
Use Patterns ◽  
Endogenous Metabolism ◽  
Gamma Hydroxybutyrate ◽  
Other Substances ◽  
History Of ◽  
Psychoactive Substance Use ◽  
Gamma Butyrolactone

Abstract Gamma-hydroxybutyrate (GHB) is misused as an intoxicant, either alone or concurrently with other substances. Because GHB is illegal, the precursor chemicals 1,4-butanediol and gamma-butyrolactone are also misused for the same effect, either through pre-ingestion alteration or endogenous metabolism to GHB. We describe a case of a 50-year-old man with a history of polysubstance misuse who experienced an overdose of GHB from gamma-butyrolactone ingestion. The patient also co-ingested a common industrial solvent, N-methyl-2-pyrrolidone (NMP). This co-ingested substance raised theoretical concern of metabolism to a GHB congener, underscoring that the emergence of new psychoactive substance use patterns requires ongoing vigilance and toxicologic confirmation.

Determining changes in new psychoactive substance use in Australia by wastewater analysis

2020 ◽  
Vol 731 ◽  
pp. 139209 ◽  
Author(s):  
Richard Bade ◽  
Jason M. White ◽  
Lynn Nguyen ◽  
Benjamin J. Tscharke ◽  
Jochen F. Mueller ◽  
...  
Keyword(s):  
Substance Use ◽  
Wastewater Analysis ◽  
Psychoactive Substance ◽  
New Psychoactive Substance ◽  
Psychoactive Substance Use

scholarly journals Identification of a new psychoactive substance in seized material: the synthetic opioidN-phenyl-N-[1-(2-phenethyl)piperidin-4-yl]prop-2-enamide (Acrylfentanyl)

2016 ◽  
Vol 9 (3) ◽  
pp. 415-422 ◽  
Author(s):  
Torben Breindahl ◽  
Andreas Kimergård ◽  
Mette Findal Andreasen ◽  
Daniel Sejer Pedersen
Keyword(s):  
Psychoactive Substance ◽  
New Psychoactive Substance
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