Coupling reaction and complex formation for the spectrophotometric determination of physiologically active catecholamines in bulk, pharmaceutical preparations and urine samples of schizophrenic patients

2010 ◽  
Vol 2 (5) ◽  
pp. 234-242 ◽  
Author(s):  
Faten A. Nour El-Dien ◽  
Eman Y. A. Frag ◽  
Gehad G. Mohamed
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Pharmaceutical Preparations ◽  
Coupling Reaction ◽  
Urine Samples ◽  
Schizophrenic Patients

scholarly journals Spectrophotometric Determination of Paracetamol in bulk and Pharmaceutical Preparations

2015 ◽  
Vol 12 (2) ◽  
pp. 317-323
Author(s):  
Baghdad Science Journal
Keyword(s):  
Sodium Hydroxide ◽  
Spectrophotometric Determination ◽  
Spectrophotometric Method ◽  
Pharmaceutical Preparations ◽  
Coupling Reaction ◽  
Reaction Conditions ◽  
Accuracy And Precision ◽  
Beer's Law ◽  
Beer’S Law

A simple, and rapid spectrophotometric method for the estimation of paracetamol has been developed. The methods is based on diazotisation of 2,4-dichloroaniline followed by a coupling reaction with paracetamol in sodium hydroxide medium. All variables affecting the reaction conditions were carefully studied. Beer's law is obeyed in the concentration range of 4-350 ?gml?1 at 490 nm .The method is successfully employed for the determination of paracetamol in pharmaceutical preparations. No interferes observed in the proposed method. Analytical parameters such as accuracy and precision have been established for the method and evaluated statistically to assess the application of the method.

scholarly journals USE OF ION ASSOCIATION COMPLEX FORMATION FOR THE SPECTROPHOTOMETRIC DETERMINATION OF ITOPRIDE HCL IN BULK AND ITS PHARMACEUTICAL PREPARATIONS

2016 ◽  
Vol 9 (1) ◽  
pp. 81
Author(s):  
P. V. Lakshmana Rao ◽  
C. Rambabu
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Pharmaceutical Preparations ◽  
Ion Association ◽  
Pharmaceutical Formulations ◽  
Spectrophotometric Methods ◽  
Itopride Hydrochloride ◽  
Soluble Ion ◽  
Association Complex

Objective: The authors report two simple, accurate and economic spectrophotometric methods A and B for the determination of Itopride hydrochloride in bulk and dosage forms.Methods: The proposed methods are based on the formation of chloroform soluble ion-associates in the presence of acidic dyes namely BPB (Method A) and BCP (Method B) exhibiting lmax at 418 and 418 nm respectively.Results: Beer’s law is found to be obeyed in the concentration range of 2.0-10.0 µg/ml and 2.0-10.0 µg/ml. The molar absorptivities are found to be 1.42x104 and 9.61x103L/mol. cm for methods A and B. These methods are successfully applied for the assay of Itopride hydrochloride in pharmaceutical formulations.

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