scholarly journals Adult‐onset diabetes in Middle Eastern immigrants to Sweden: Novel subgroups and diabetic complications—The All New Diabetes in Scania cohort diabetic complications and ethnicity

2020 ◽  
Author(s):  
Louise Bennet ◽  
Christopher Nilsson ◽  
Dina Mansour‐Aly ◽  
Anders Christensson ◽  
Leif Groop ◽  
...  
Keyword(s):  
Diabetic Complications ◽  
Middle Eastern ◽  
Adult Onset ◽  
Onset Diabetes ◽  
Adult Onset Diabetes ◽  
Middle Eastern Immigrants

scholarly journals Factors Associated with Risk of Diabetic Complications in Novel Cluster-Based Diabetes Subgroups: A Japanese Retrospective Cohort Study

2020 ◽  
Vol 9 (7) ◽  
pp. 2083 ◽  
Author(s):  
Hayato Tanabe ◽  
Haruka Saito ◽  
Akihiro Kudo ◽  
Noritaka Machii ◽  
Hiroyuki Hirai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cluster Analysis ◽  
Cohort Study ◽  
Diabetic Complications ◽  
Retrospective Cohort Study ◽  
Japanese Population ◽  
Retrospective Cohort ◽  
Adult Onset ◽  
Onset Diabetes ◽  
Adult Onset Diabetes

Diabetes is a complex and heterogeneous disease, making the prediction of the risks of diabetic complications challenging. Novel adult-onset diabetes subgroups have been studied using cluster analysis, but its application in East Asians remains unclear. We conducted a retrospective cohort study to elucidate the clinical utility of cluster-based subgroup analysis in the Japanese population. Cluster analysis based on anti-glutamate decarboxylase antibody (GAD antibody) levels, age at diagnosis, body mass index (BMI), hemoglobin A1c (A1c), and homeostatic model assessment 2 estimates of β-cell function and insulin resistance was performed in 1520 diabetic patients. The risk of developing diabetic complications was analyzed using Kaplan–Meier analysis and the Cox proportional hazards model. By cluster analysis, we identified five distinct subgroups of adult-onset diabetes in the Japanese population. The risk of diabetic complications varied greatly among the clusters. Patients with severe autoimmune diabetes or severe insulin deficiency diabetes were at an increased risk of diabetic retinopathy, and those with severe insulin resistant diabetes (SIRD) had the highest risk of developing diabetic kidney disease (DKD). After adjusting for uncorrectable and correctable risk factors, SIRD was found to be an independent risk factor for DKD. In conclusion, we identified five subgroups of adult-onset diabetes and the risk factors for diabetic complications in the Japanese population. This new classification system can be effective in predicting the risk of diabetic complications and for providing optimal treatment.

Novel clusters of adult-onset Diabetes: Casuistic from an Endocrinology Department

2019 ◽  
Author(s):  
Vitoria Duarte ◽  
Catarina Ivo ◽  
David Verissimo ◽  
Joao Silva ◽  
Luis Lopes ◽  
...  
Keyword(s):  
Adult Onset ◽  
Onset Diabetes ◽  
Adult Onset Diabetes

scholarly journals Case report: adult onset diabetes with partial pancreatic agenesis and congenital heart disease due to a de novo GATA6 mutation

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Begona Sanchez-Lechuga ◽  
Muhammad Saqlain ◽  
Nicholas Ng ◽  
Kevin Colclough ◽  
Conor Woods ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Case Report ◽  
Congenital Heart ◽  
De Novo ◽  
Adult Onset ◽  
Onset Diabetes ◽  
Adult Onset Diabetes ◽  
Pancreatic Agenesis

Lifecourse weight patterns and adult-onset diabetes: the Glasgow Alumni and British Women's Heart and Health studies

2005 ◽  
Vol 30 (3) ◽  
pp. 507-512 ◽  
Author(s):  
M Jeffreys ◽  
D A Lawlor ◽  
B Galobardes ◽  
P McCarron ◽  
S Kinra ◽  
...  
Keyword(s):  
Adult Onset ◽  
Onset Diabetes ◽  
Adult Onset Diabetes ◽  
Health Studies

Extrainsular mechanisms of glucose disposal in adult-onset diabetes

1971 ◽  
Vol 261 (4) ◽  
pp. 197-205
Author(s):  
MAXIMILIAN FABRYKANT ◽  
MAXWELL L. GELFAND ◽  
AURA A. ORTEGA ◽  
ERNEST R. BUFFONE ◽  
JOSE V. MANRIQUE
Keyword(s):  
Glucose Disposal ◽  
Adult Onset ◽  
Onset Diabetes ◽  
Adult Onset Diabetes

Management of Adult-Onset Diabetes

1972 ◽  
Vol 52 (1) ◽  
pp. 63-68 ◽  
Author(s):  
Frederick C. Goetz
Keyword(s):  
Adult Onset ◽  
Onset Diabetes ◽  
Adult Onset Diabetes
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