Association of cognitive performance with the metabolic syndrome and with glycaemia in middle-aged and older European men: the European Male Ageing Study

2010 ◽  
Vol 26 (8) ◽  
pp. 668-676 ◽  
Author(s):  
Jos Tournoy ◽  
David M. Lee ◽  
Neil Pendleton ◽  
Terence W. O'Neill ◽  
Daryl B. O'Connor ◽  
...  
2010 ◽  
Vol 6 ◽  
pp. S457-S458
Author(s):  
Jos Tournoy ◽  
David Lee ◽  
Neil Pendleton ◽  
Terence O'Neill ◽  
Daryl O'Connor ◽  
...  

2017 ◽  
Vol 25 (6) ◽  
pp. 662-671 ◽  
Author(s):  
Margot J. Overman ◽  
Neil Pendleton ◽  
Terence W. O'Neill ◽  
Gyorgy Bartfai ◽  
Felipe F. Casanueva ◽  
...  

2010 ◽  
Vol 20 (6) ◽  
pp. 312-315
Author(s):  
Angelos A. Evangelopoulos ◽  
Natalia G. Vallianou ◽  
Demosthenes B. Panagiotakos ◽  
Aikaterini T. Georgiou ◽  
Georgios A. Zacharias ◽  
...  

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Michael McManus ◽  
Daniela Markovic ◽  
Natalie Valle ◽  
Bruce Ovbiagele ◽  
Amytis Towfighi

BACKGROUND: Metabolic syndrome (MetS), a constellation of cardiometabolic risk factors clustering together, affects >47 million US adults and has been independently linked to primary and recurrent stroke risk. Prevalence and trends in MetS among stroke survivors in the United States are unknown. OBJECTIVES: To evaluate recent temporal trends in age and sex-specific MetS prevalence among adults with/without stroke in the US. METHODS: Prevalence of MetS was assessed among fasting adults ≥35 years who participated in National Health and Nutrition Examination Surveys 1999-2010 (n=9,343). Prevalence estimates were weighted to obtain nationally representative estimates (n=430,371,669). MetS was defined by the 2009 harmonized definition. Stroke was determined by self-report. RESULTS: In all groups except men 35-64 years, MetS prevalence was similar among adults with and without stroke in 1999-2002 (Table). MetS prevalence rates were flat from 1999 to 2010 among those without stroke, but increased among stroke survivors, such that up to 80% of men and 86% of women with stroke had MetS, with the greatest rise among the middle-aged. Stroke survivors aged 35-64 years were ~3 times more likely to have MetS than their counterparts without stroke (OR 3.24, 95% CI 1.60-6.55 for men and OR 2.55, 95% CI 1.45-4.50 for women). DISCUSSION: Due to a differential rise in MetS in stroke survivors over the last 10 years, as many as 9 out of 10 stroke survivors now have MetS, suggesting that Mets may increasingly be placing people at risk for stroke. Intensified efforts aimed at identifying and treating MetS, especially among middle-aged individuals, may be warranted to avert stroke risk.


Diabetologia ◽  
2004 ◽  
Vol 47 (8) ◽  
Author(s):  
D.E. Laaksonen ◽  
L. Niskanen ◽  
K. Nyyss�nen ◽  
K. Punnonen ◽  
T.-P. Tuomainen ◽  
...  

2010 ◽  
Vol 38 (2) ◽  
pp. 370-377 ◽  
Author(s):  
ABDELOUAHID TAJAR ◽  
TERENCE W. O’NEILL ◽  
DAVID M. LEE ◽  
DARYL B. O’CONNOR ◽  
GIOVANNI CORONA ◽  
...  

Objective.To determine whether musculoskeletal pain was associated with impaired sexual function in a population sample of middle-aged and older men.Methods.The European Male Ageing Study (EMAS), a multicenter population-based study of men aged 40–79 years, was used to investigate this hypothesis. A questionnaire asked about the presence and duration of musculoskeletal pain, allowing subjects to be classified into 1 of 3 groups: those reporting chronic widespread pain (CWP), those reporting pain but not CWP (“some pain”), and those with no pain. Subjects completed a sexual function questionnaire from which 3 domains were considered: overall sexual functioning (OSF), sexual functioning-related distress (SFD), and change in sexual functioning compared to 1 year ago (CSF).Results.A total of 3206 men [mean age 60 (SD 11) yrs] had complete data on pain status. Of these, 8.7% had CWP and 50.34% had “some pain.” Pain was associated with lower OSF, and higher SFD and CSF scores. After adjustment for putative confounding factors, the associations became non-significant with OSF and CSF but persisted for SFD. Associations between pain status and some items within the sexual functioning domains, including frequency of sexual intercourse, frequency of morning erections, sexual desire, and orgasm were also significant, although these associations varied by pain status.Conclusion.Musculoskeletal pain is associated with several aspects of sexual functioning. These relationships differ depending on the extent of the pain (chronic or not) and are also largely confounded by other health-related factors, primarily depression.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Olimpia Arellano-Campos ◽  
Donaji V. Gómez-Velasco ◽  
Omar Yaxmehen Bello-Chavolla ◽  
Ivette Cruz-Bautista ◽  
Marco A. Melgarejo-Hernandez ◽  
...  

Author(s):  
Alfonso Bellia ◽  
Bruno Ruscello ◽  
Rolando Bolognino ◽  
Gianluca Briotti ◽  
Paolo Roberto Gabrielli ◽  
...  

AbstractWe investigated early effects of Whole-Body Electromyostimulation added to hypocaloric diet on metabolic syndrome features in sedentary middle-aged individuals. We randomly assigned 25 patients to Whole-Body Electromyostimulation plus caloric restriction or caloric restriction alone for 26 weeks. Anthropometrics, blood pressure, fasting glucose and insulin, HOMA-IR, glycated hemoglobin, lipids, uric acid, creatinphosphokynase, C-reactive protein were assessed. Body composition was evaluated with direct-segmental, multi-frequency Bioelectrical Impedance Analysis. Both groups lost approximately 10% of weight, with similar effects on waist circumference and fat mass. Change in free-fat mass was significantly different between groups (caloric restriction −1.5±0.2 vs. Whole-Body Electromyostimulation plus caloric restriction +1.1±0.4 kg, p=0.03). Whole-Body Electromyostimulation plus caloric restriction group experienced greater percent reductions in insulin (−45.5±4.4 vs. −28.2±3.6%, p=0.002), HOMA-IR (–51.3±3.2 vs. –25.1±1.8%, p=0.001), triglycerides (−22.5±2.9 vs. −4.1±1.6%, p=0.004) and triglycerides/HDL (p=0.028). Subjects trained with Whole-Body Electromyostimulation had also significant improvement in systolic pressure (138±4 vs. 126±7 mmHg, p=0.038). No discontinuations for adverse events occurred. In middle-aged sedentary subjects with the metabolic syndrome, Whole-Body Electromyostimulation with caloric restriction for 26 weeks can improve insulin-resistance and lipid profile compared to diet alone. Further studies are needed to ascertain long-term efficacy and feasibility of this approach in individuals with the metabolic syndrome.


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