Influence of age and short-term starvation on the ATPase activity in the developing rat brain

1978 ◽  
Vol 11 (6) ◽  
pp. 587-593 ◽  
Author(s):  
J. Mourek ◽  
F. ??astn�
Keyword(s):  
Atpase Activity ◽  
Rat Brain ◽  
Short Term ◽  
Developing Rat

Sodium Nitrite Alone Protects the Brain Microsomal Ca2+-ATPase Against Potassium Cyanide-induced Neurotoxicity In Rats

1997 ◽  
Vol 17 (6) ◽  
pp. 543-546 ◽  
Author(s):  
O. O. Odunuga ◽  
G. A. Adenuga
Keyword(s):  
Oral Administration ◽  
Atpase Activity ◽  
Rat Brain ◽  
Sodium Nitrite ◽  
Specific Activity ◽  
Potassium Cyanide ◽  
Protective Role ◽  
Short Term ◽  
Significant Difference ◽  
The Brain

The effect of a short-term oral administration of potassium cyanide (KCN) (200 ppm in diet) with or without sodium nitrite (NaNO2) pretreatment on rat brain microsomal Ca2± ATPase was investigated. The specific activity value of the enzyme significantly decreased (p<0.05) by 50% compared with control and by 63% for KCN-treated rats compared with KCN-treated rats pretreated with NaNO2. There was no significant difference at the h=0.05 level between the values obtained for the control and KCN-treated rats pretreated with NaNO2. These results show both that feeding lowers brain microsomal Ca2+-ATPase activity and that NaNO2 has a protective role (antidote function) in that respect.

Regulation of tubulin by triiodothyronine in hypothyroid rat brain

1985 ◽  
Vol 5 (8) ◽  
pp. 643-648 ◽  
Author(s):  
Anjana Mazumder ◽  
Kamal Das ◽  
Pranab K. Sarkar
Keyword(s):  
Protein Synthesis ◽  
Rat Brain ◽  
Brain Maturation ◽  
Normal Brain ◽  
Neonatal Brain ◽  
Organ Cultures ◽  
Postnatal Brain ◽  
Enhanced Sensitivity ◽  
Brain Exposure ◽  
Developing Rat

The effect of T3 (triiodothyronine) on the induction of tubulin in hypothyroid developing rat brain has been examined using organ cultures of brains from late fetal, neonatal and postnatalrats. The neonatal brain displayed maximum sensitivity to T3. Hypothyroidism resulted in a 26% decline in the level of tubulin in the neonatal brain as opposed to a 5–15% decline in the fetal or postnatal brain. Exposure of the hypothyroi d neonatal brain to T3 for 2 h in culture led to a 61% rise in the level of tubulin in contrast to a 41% increase seen in the case of normal brain. Total protein synthesis was not significantly affected. The preferential decline of tubulin in the neonatal hypothyroid brain, its enhanced sensitivity to T3 compared to normal brain, and the coincidence of the period of sensitivity to that of brain maturation indicate that the regulation of the level of tubulin by T3 in the developing brain is a natural ontogenic phenomenon.

scholarly journals Effect of Hypoxic-Ischemic Injury on Serine Palmitoyltransferase Activity in the Developing Rat Brain

Pathobiology ◽  
2008 ◽  
Vol 75 (6) ◽  
pp. 330-334 ◽  
Author(s):  
Masaki Daigo ◽  
Yasuhiro Arai ◽  
Kyoichi Oshida ◽  
Yohei Kitamura ◽  
Masaharu Hayashi ◽  
...  
Keyword(s):  
Rat Brain ◽  
Ischemic Injury ◽  
Serine Palmitoyltransferase ◽  
Developing Rat ◽  
Hypoxic Ischemic Injury

scholarly journals Ultracytochemical study of the ouabain-sensitive, K-dependent p-nitrophenylphosphatase (Na-K-ATPase) activity in the developing rat kidney.

1982 ◽  
Vol 15 (3) ◽  
pp. 421-438 ◽  
Author(s):  
HIROSHI MAYAHARA ◽  
TAKAO ANDO ◽  
YOSHIMARO ISHIKAWA ◽  
Kazuo OGAWA
Keyword(s):  
Atpase Activity ◽  
Rat Kidney ◽  
Developing Rat
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