scholarly journals Microbiota of newborn meconium is associated with maternal anxiety experienced during pregnancy

2019 ◽  
Vol 61 (5) ◽  
pp. 640-649 ◽  
Author(s):  
Jianzhong Hu ◽  
Jenny Ly ◽  
Wei Zhang ◽  
Yonglin Huang ◽  
Vivette Glover ◽  
...  
Keyword(s):  
Maternal Anxiety

Maternal anxiety and depression in pregnancy and DNA methylation of the NR3C1 glucocorticoid receptor gene

Epigenomics ◽  
2020 ◽  
Author(s):  
Alexandra E Dereix ◽  
Rachel Ledyard ◽  
Allyson M Redhunt ◽  
Tessa R Bloomquist ◽  
Kasey JM Brennan ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Depressive Symptoms ◽  
Trait Anxiety ◽  
Cpg Island ◽  
Depression Scale ◽  
Maternal Anxiety ◽  
Anxiety And Depression ◽  
Pregnancy Anxiety ◽  
Glucocorticoid Receptor Gene ◽  
Island Shore

Aim: To quantify associations of anxiety and depression during pregnancy with differential cord blood DNA methylation of the glucorticoid receptor ( NR3C1). Materials & methods: Pregnancy anxiety, trait anxiety and depressive symptoms were collected using the Pregnancy Related Anxiety Scale, State-Trait Anxiety Index and Edinburgh Postnatal Depression Scale, respectively. NR3C1 methylation was determined at four methylation sites. Results: DNA methylation of CpG 1 in the NR3C1 CpG island shore was higher in infants born to women with high pregnancy anxiety (β 2.54, 95% CI: 0.49–4.58) and trait anxiety (β 1.68, 95% CI: 0.14–3.22). No significant association was found between depressive symptoms and NR3C1 methylation. Conclusion: We found that maternal anxiety was associated with increased NR3C1 CpG island shore methylation.

Transactional relations between maternal anxiety and toddler anxiety risk through toddler‐solicited comforting behavior

2021 ◽  
Author(s):  
Elizabeth J. Kiel ◽  
Elizabeth M. Aaron ◽  
Sydney M. Risley ◽  
Aaron M. Luebbe
Keyword(s):  
Maternal Anxiety

scholarly journals Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

2021 ◽  
Author(s):  
Sara Sammallahti ◽  
Andrea P. Cortes Hidalgo ◽  
Samuli Tuominen ◽  
Anni Malmberg ◽  
Rosa H. Mulder ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Maternal Anxiety

scholarly journals Exploring the Impact of Restricted Partners’ Visiting Policies on Non-Infected Mothers’ Mental Health and Breastfeeding Rates during the COVID-19 Pandemic

2021 ◽  
Vol 18 (12) ◽  
pp. 6347
Author(s):  
Daniela Morniroli ◽  
Alessandra Consales ◽  
Lorenzo Colombo ◽  
Elena Nicoletta Bezze ◽  
Lidia Zanotta ◽  
...  
Keyword(s):  
Mental Health ◽  
Perinatal Care ◽  
Mode Of Delivery ◽  
Maternal Anxiety ◽  
Specific Situation ◽  
Caregiver Support ◽  
Anxiety Levels ◽  
Breastfeeding Rates ◽  
The Impact ◽  
Mean State

Changes in perinatal care occurring during the coronavirus disease 2019 (COVID-19) pandemic may negatively affect mothers’ mental health and breastfeeding. This study, performed between April and May 2020, aimed to investigate the effect of restricted partners’ visiting policies on non-infected mother’s anxiety symptoms, the perceived postpartum support, and the breastfeeding outcomes at discharge. A cross-sectional study was conducted in a neonatal tertiary referral center in northern Italy during Italy’s lockdown. We enrolled mothers with a negative nasopharyngeal swab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), adequate oral and written comprehension of the Italian language, and absence of underlying maternal or neonatal clinical conditions. Maternal anxiety levels were assessed through the State-Trait Anxiety Inventory-Form Y (STAI-Y). Maternal perception of staff’s support was evaluated by the Nurse Parent Support Tool (NPST). A STATE-A (concurrent emotional state after a specific situation) score ≥ 40 was considered indicative of clinically significant symptoms of anxiety. A total of 109 mothers completed the study. Mean STATE-A score was ≥40 in 42% of mothers, and median NPST score was 4.23. Mothers separated from their partner had a mean STATE-A score ≥ 40 in a higher percentage of cases than those who were not (51% vs. 30%, p = 0.03) and a lower perception of caregiver support. A NPST score ≤4.23, partner ‘s absence during the hospital stay and primiparity were independently associated with a STATE-A score ≥ 40. Breastfeeding rates at discharge were not influenced by maternal anxiety levels and partner’s restricted policies. Instead, they were influenced by mode of delivery, a well-known risk factor, and pre-pandemic intention to breastfeed. Our study demonstrates the positive impact of a partner’s presence on maternal mental health and perception of caregiver support.

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