Prenatal programming of postnatal plasticity for externalizing behavior: Testing an integrated developmental model of genetic and temperamental sensitivity to the environment

Irene Tung; Julia E. Morgan; Amanda N. Noroña; Steve S. Lee

doi:10.1002/dev.21549

Prenatal programming of postnatal plasticity for externalizing behavior: Testing an integrated developmental model of genetic and temperamental sensitivity to the environment

Developmental Psychobiology ◽

10.1002/dev.21549 ◽

2017 ◽

Vol 59 (8) ◽

pp. 984-996 ◽

Cited By ~ 1

Author(s):

Irene Tung ◽

Julia E. Morgan ◽

Amanda N. Noroña ◽

Steve S. Lee

Keyword(s):

Externalizing Behavior ◽

Developmental Model ◽

Prenatal Programming

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Instantiating the multiple levels of analysis perspective in a program of study on externalizing behavior

Development and Psychopathology ◽

10.1017/s0954579412000508 ◽

2012 ◽

Vol 24 (3) ◽

pp. 1003-1018 ◽

Cited By ~ 63

Author(s):

Theodore P. Beauchaine ◽

Lisa M. Gatzke-Kopp

Keyword(s):

Middle Childhood ◽

Externalizing Behavior ◽

Developmental Psychopathology ◽

Personality Development ◽

Developmental Model ◽

Self Report ◽

Levels Of Analysis ◽

Quarter Century ◽

Trait Impulsivity ◽

Multiple Levels

AbstractDuring the last quarter century, developmental psychopathology has become increasingly inclusive and now spans disciplines ranging from psychiatric genetics to primary prevention. As a result, developmental psychopathologists have extended traditional diathesis–stress and transactional models to include causal processes at and across all relevant levels of analysis. Such research is embodied in what is known as the multiple levels of analysis perspective. We describe how multiple levels of analysis research has informed our current thinking about antisocial and borderline personality development among trait impulsive and therefore vulnerable individuals. Our approach extends the multiple levels of analysis perspective beyond simple Biology × Environment interactions by evaluating impulsivity across physiological systems (genetic, autonomic, hormonal, neural), psychological constructs (social, affective, motivational), developmental epochs (preschool, middle childhood, adolescence, adulthood), sexes (male, female), and methods of inquiry (self-report, informant report, treatment outcome, cardiovascular, electrophysiological, neuroimaging). By conducting our research using any and all available methods across these levels of analysis, we have arrived at a developmental model of trait impulsivity that we believe confers a greater understanding of this highly heritable trait and captures at least some heterogeneity in key behavioral outcomes, including delinquency and suicide.

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